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Osteoporosis NL @osteoporosis-nl.bsky.social · 21h

The phenotype of pelvic and acetabular fractures in adults aged 50 and older: a national database analysis in the Netherlands. MI Lommerse et al. Osteoporos Int 2026 Oct 5 shorturl.at/scjUO ...fine paper ...pelvic fractures more closely linked to frailty and osteoporosis, most apparent in females

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Osteoporosis NL @osteoporosis-nl.bsky.social · 21h

What's New in Osteoporosis and Fragility Fractures? RMY Wong et al. J Bone Joint Surg Am 2026 Oct 5. shorturl.at/Xr3Gp ... paper covers some of the latest trends, studies, and interventions for fragility fractures and osteoporosis

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Osteoporosis NL @osteoporosis-nl.bsky.social · 21h

Trends in risk of subsequent fracture and post-fracture treatment among post-menopausal US women. KE Hurwitz et al. Am J Med 2026 Oct 5 shorturl.at/N0J0g ...subsequent fracture risk was high, yet treatment initiation remained low ...nasty results keep turning up

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Osteoporosis NL @osteoporosis-nl.bsky.social · 07/10/2026

The incretin-bone axis: molecular mechanisms and clinical implications. A Muscarà et al. Front Endocrinol 5 Oct 2026 shorturl.at/kdROy ...fine update ...effects of GIP and GLP-1

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Osteoporosis NL @osteoporosis-nl.bsky.social · 07/10/2026

13-year follow-up of a prenatal high-dose vitamin D supplementation did not show any lasting effect on offspring BMC/BMD; secondary analysis of a RCT. N Brustad et al. Lancet Reg Health Eur 2026 Sep 25 shorturl.at/IAION

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Osteoporosis NL @osteoporosis-nl.bsky.social · 07/10/2026

Adults with OI show in cross-sectional study increased prevalence of valvular heart disease, unruptured intracranial aneurysms, and possibly intracranial arterial tortuosity and cortical atrophy. Y Kodama et al. Vasc Med 2026 Oct 4 shorturl.at/6jgWS ..regardless of disease severity

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Osteoporosis NL @osteoporosis-nl.bsky.social · 06/10/2026

Denosumab: efficacy, safety, persistence and sequential strategies; a syst.review. NA Laursen et al. Osteoporos Int 2 Oct 2026 shorturl.at/WQyEU ... discontinuing DMAB requires long-term treatment planning, and the timely initiation of appropriate sequential therapy is essential

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Osteoporosis NL @osteoporosis-nl.bsky.social · 06/10/2026

Calcitonin Gene-Related Peptide in bone repair and musculoskeletal pain: scoping review skeletal regeneration, and CGRP-targeted therapies. S Baral et al. Calcif Tissue Int 1 Oct 2026 shorturl.at/1Pvv7 ...anti-CGRP therapy in musculoskeletal patients is not currently supported by clinical evidence

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Osteoporosis NL @osteoporosis-nl.bsky.social · 06/10/2026

Romosozumab prescribing in relation to CVD history in Japan; patients with CVD history had higher probabilities of treatment discontinuation, particularly among women. Yuki Fujita et al. Calcif Tissue Int 2026 Oct 3 shorturl.at/EkOun

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Osteoporosis NL @osteoporosis-nl.bsky.social · 05/10/2026

OP medications in patients with shoulder OA were associated with a reduced incidence of total shoulder arthroplasty without differences between denosumab and bisphosphonates.TH Shehadeh et al. Osteoporos Int 29 Sep 2026 shorturl.at/1VqNJ ...TriNetX database

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Osteoporosis NL @osteoporosis-nl.bsky.social · 05/10/2026

Sex- and age-specific patterns in bone, muscle, and fat across adulthood and their relation to osteosarcopenic adiposity phenotype: a cross-sectional study. JZ Ilich et al. Geroscience 2026 Sep 30 shorturl.at/NWaqe ... associated with earlier adverse patterns and greater instability

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Osteoporosis NL @osteoporosis-nl.bsky.social · 05/10/2026

Exosome-mediated muscle-bone crosstalk: mechanisms and therapeutic potential. D Chen et al. J Transl Med 2026 Sep 24 shorturl.at/gHzeI ...fine interesting update

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Osteoporosis NL @osteoporosis-nl.bsky.social · 04/10/2026

How physical disuse and mechanical unloading disrupt the muscle–bone–adipose axis, accelerating musculoskeletal decay and osteosarcopenia in older adults. JM Reyes et al. Exp Physiol 2026 Sep 28 shorturl.at/pszje ...narrative fine review ...available multimodal interventions

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Osteoporosis NL @osteoporosis-nl.bsky.social · 04/10/2026

Shared genetic basis of sarcopenia and osteoporosis: insights from GWAS and multi-omics analyses. Kaixi Ding et al. J Bone Miner Metab 2026 Sep 20. shorturl.at/sx8uL … share a significant genetic basis as well as partially overlapping molecular networks

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Osteoporosis NL @osteoporosis-nl.bsky.social · 04/10/2026

Exercise-mediated muscle-bone crosstalk in osteosarcopenia: potential integration through the LIF/LIFR/STAT3 signaling axis. Zehui Yang et al. Prog Biophys Mol Biol 2026 Sep 26 shorturl.at/GRE75 …should currently be considered a biologically plausible candidate mechanism

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Osteoporosis NL @osteoporosis-nl.bsky.social · 02/10/2026

Intestinal-Bone Axis Mediated by Bifidobacterium: Mechanistic Analysis and Therapeutic Potential in Osteoporosis. Fadong Li et al. Microorganisms 2026 Sep 8 shorturl.at/QL7qy …excellent update … causal relationships await validation in large-scale prospective cohort studies and RCTs

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Osteoporosis NL @osteoporosis-nl.bsky.social · 02/10/2026

Research Progress on Mechanisms of Milk-Derived Functional Components in Regulating Bone Health and the Gut-Bone Axis. Henigul Osman et al. Nutrients 2026 Sep 10 shorturl.at/pZmIo ...fine review

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Osteoporosis NL @osteoporosis-nl.bsky.social · 02/10/2026

Obesity and Osteoporotic Fractures: Solving the Paradox. K Agarwal & S Patra. Indian J Endocrinol Metab 31 Aug 2026. shorturl.at/DzdEe ...higher BMI is associated with increased BMD due to mechanical loading, but it does not uniformly protect against fractures

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Osteoporosis NL @osteoporosis-nl.bsky.social · 01/10/2026

Equivalent 12-month BMD response to Romosozumab in patients aged ≥ 85 and < 85 Years: real-world cohort study (n = 417) from Northern Japan. R Nakano et al. Calcified Tiss Int 25 Sept 2026 shorturl.at/H27Dv ... Romosozumab should not be withheld from very elderly on basis of age alone

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Osteoporosis NL @osteoporosis-nl.bsky.social · 01/10/2026

Chronic hyponatremia and skeletal vulnerability: bone loss, fragility fracture risk, and therapeutic uncertainties. LM Almeida Corrêa et al. Osteoporos Int 2026 Sep 24 shorturl.at/wV7C7 ...clinically meaningful modifier of fracture-risk interpretation and secondary-cause assessment

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Osteoporosis NL @osteoporosis-nl.bsky.social · 01/10/2026

Skeletal pathologies by PLS3 inactivation are associated with impaired cortical bone integrity. O Windels et al. JBMR 24 Sep 2026 shorturl.at/xNHnj ...PLS3 inactivation predominantly affects cortical bone parameters in mice and humans ... anti-sclerostin therapy could be effective

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Osteoporosis NL @osteoporosis-nl.bsky.social · 30/09/2026

Real-World Effectiveness of Burosumab Versus Oral Phosphate and Active Vitamin D in Adults With X-Linked Hypophosphatemia (XLH): A 3-Year Follow-Up of the XLH Disease Monitoring Program. W Steven et al. JBMR 23 Sep 2026 shorturl.at/kFhaB …continued benefits of burosumab

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Osteoporosis NL @osteoporosis-nl.bsky.social · 30/09/2026

Levothyroxine use and bone loss: Longitudinal analysis among euthyroid men and women from the Baltimore Longitudinal Study of Aging. E Ghotbi et al. Bone 22 Sep 2026 shorturl.at/7VdVe may be a factor in bone loss, particularly among women in late-middle and early old-age

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Osteoporosis NL @osteoporosis-nl.bsky.social · 30/09/2026

Dose matters: haploinsufficiency in osteogenesis imperfecta. A Sclocco et al. Nature Rev Endocrinol 27 Jul 2026 shorturl.at/Ao3LR ... defining knowledge gaps that future investigations of this disease should aim to address

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Osteoporosis NL @osteoporosis-nl.bsky.social · 29/09/2026

Multiscale assessment of glucocorticoid-induced alterations across bone marrow and mineralized bone in human iliac crest biopsies from 21 patients without concomitant anti-osteoporotic treatment versus 13 controls. P Sihota et al. JBMR 23 Sep 2026 shorturl.at/dwQQq …excellent unique study!

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Osteoporosis NL @osteoporosis-nl.bsky.social · 29/09/2026

Lower BMD chest CT associated with modestly accelerated regional white matter injury and faster cognitive decline, particularly among participants with diabetes. Multi-Ethnic Study of Atherosclerosis. S Momtazmanesh et al. Radiology 2026 22Sep 2026 shorturl.at/M1xj8 ...no causal relation

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Osteoporosis NL @osteoporosis-nl.bsky.social · 28/09/2026

Effects of Low Magnitude Vibration on Mesenchymal Stem Cell Osteogenic Potential and Phenotype. VV Maldonado et al. Biochimie 2026 Sep 23 shorturl.at/3wuuo …PIEZO1 channel is important for LMV-induced osteogenesis in BM-MSCs

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Osteoporosis NL @osteoporosis-nl.bsky.social · 28/09/2026

Cellular senescence and the SASP in skeletal ageing: convergent mechanisms of progressive bone loss in osteoporosis. H Liu & B Lei. Biogerontology 22 Sep 2026 shorturl.at/ctYK1 ... review examining the evidence

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Osteoporosis NL @osteoporosis-nl.bsky.social · 27/09/2026

Primary Hyperparathyroidism in Celiac Disease: Diagnostic Challenges and Therapeutic Strategies. QV Luong et al. Nutrients 2026 Sep 21 shorturl.at/SKQQN ... highlights a gap in our understanding of the pathogenesis linking these two conditions ...recommendations

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Osteoporosis NL @osteoporosis-nl.bsky.social · 27/09/2026

Parathyroid Carcinoma and Primary Hyperparathyroidism: Trends and Outcomes. S Baek et al. Endocr Relat Cancer 2026 Sep 23 shorturl.at/QyAxA ... rising burden of parathyroid disease in Korea and underscore the need for cardiometabolic risk surveillance

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Osteoporosis NL @osteoporosis-nl.bsky.social · 27/09/2026

Bone-modifying agents may alter biochemical presentation and operative findings in primary hyperparathyroidism. AC Chmiel et al. Surgery 2026 Sep 1 shorturl.at/Life8 ... associated with a distinct biochemical profile and a higher prevalence of multigland disease

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Osteoporosis NL @osteoporosis-nl.bsky.social · 27/09/2026

How frequently does parathyroidectomy and adjuvant treatment lead to clinically meaningful changes in bone mineral density? A multi-institutional study. N Druar et al. Surgery 2026 Sep 1 shorturl.at/BO4s0 ... meaningful bone mineral density improvement in 45.2% of patients

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Osteoporosis NL @osteoporosis-nl.bsky.social · 26/09/2026

Reduced BMD is associated with impaired auditory function in PMP women, worsening progressively from normal BMD to osteopenia and osteoporosis, independently of age, BMI and duration of menopause. SA Mkrtchyan et al. Am J Otolaryngol 2026 Sep 19 shorturl.at/7mVi4

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Osteoporosis NL @osteoporosis-nl.bsky.social · 26/09/2026

Mathematical model describing interactions between renin-angiotensin system (RAS), calciotropic hormones, calcium regulation, and bone remodeling. MM Stad et al. PLoS Comput Biol 2026 Sep 22 shorturl.at/K8rPe …angiotensin receptor blockers may increase BMD during PMP estrogen decline

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Osteoporosis NL @osteoporosis-nl.bsky.social · 26/09/2026

Herbal Therapeutics in Osteoporosis: Mechanisms, Evidence, and Translational Potential. EV Moradi et al. Phytother Res 2026 Sep 22. shorturl.at/vxxK3 ... narrative extensive review consolidates mechanistic and translational evidence for eight botanicals ...

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Osteoporosis NL @osteoporosis-nl.bsky.social · 25/09/2026

COPD is significantly more toxic to the skeleton than T2DM, and their coexistence amplifies fracture susceptibility compared to T2DM alone; nationwide cohort Taiwan. Fu-Shun Ko et al. Chest 2026 Sep 21 shorturl.at/Rjuuh ...especially in male patients with COPD

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Osteoporosis NL @osteoporosis-nl.bsky.social · 25/09/2026

Novel bioactive compounds in the treatment of osteoporosis: chemistry-driven discovery from preclinical validation to clinical translation. H Fan & S Jin. Front Chem 18 Sep 2026 doi.org/10.3389/fche... ...intersting update

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Osteoporosis NL @osteoporosis-nl.bsky.social · 25/09/2026

A conceptual model of a pathway from osteoporosis to atherosclerosis: a scoping review. GL Klein et al Bone 16 Sept 2026 shorturl.at/1PerB … high bone resorption appears to be a factor in the development of atherosclerotic vascular calcification

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Reposted by Osteoporosis NL

Roel Maalderink @roelmaalderink.bsky.social · 24/09/2026

Meta wil niet dat je deze video ziet. Ik herhaal: Meta wil níet dat je deze video ziet.

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Osteoporosis NL @osteoporosis-nl.bsky.social · 24/09/2026

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Osteoporosis NL @osteoporosis-nl.bsky.social · 24/09/2026

Skeletal effects of 5-year high-dose cyclical etidronate in patients aged ≥50 years with pseudoxanthoma elasticum. M Haverkamp et al. Bone 15 Sep 2026 shorturl.at/zKVSZ ...did not negatively affect skeletal integrity and metabolism and prevented bone loss at both the spine and the hip

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Osteoporosis NL @osteoporosis-nl.bsky.social · 24/09/2026

Osteoporosis and Skeletal Fragility in non-Metastatic Pheochromocytomas and Paragangliomas: The Adrenergic-Skeletal Axis. A Vassallo & F Raggini. Calcif Tissue Int 18 Sep 2026 shorturl.at/MFSkR ...excellent update pathophysiology, clinical features, and management

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Osteoporosis NL @osteoporosis-nl.bsky.social · 23/09/2026

Shared genetic basis of sarcopenia and osteoporosis: insights from GWAS and multi-omics analyses. K Ding et al. J Bone Miner Metab 2026 Sep 20 shorturl.at/w7Hhz ...from UK Biobank and FinnGen data ...fine study maps the shared genetic architecture and key molecular networks

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Osteoporosis NL @osteoporosis-nl.bsky.social · 23/09/2026

Anti-osteoporotic pharmacotherapy and muscle outcomes in osteosarcopenia. D-J Lim & MK Kang. Calcif Tissue Int 18 Sep 2026 shorturl.at/M9En0 ...no approved anti-osteoporotic drug can currently be claimed as established pharmacological treatment for osteosarcopenia

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Osteoporosis NL @osteoporosis-nl.bsky.social · 23/09/2026

Reframing sarcopenia as a disease of the ageing motor system. LB Orssatto et al. Lancet Healthy Longev 2026 Aug 28 shorturl.at/pRf1z ... disease model should evolve to reflect the distributed biology of sarcopenia, guiding integrated assessment, mechanistic stratification, and therapies

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Reposted by Osteoporosis NL

Jennifer Shin - WTAF @jennifershin.bsky.social · 14/09/2025

All 3 do not recognize the ICC.

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