More on germline mutations in patients with NETs
453 patients with NETs, 11.5% with a germline pathogenic or likely pathogenic variant, most commonly in MEN1 (3.5%). Other alterations noted were PALB2, SDHB, BRIP1 and MUTYH.
A nice addition to the lit.
onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com
Germline Mutation Landscape of Neuroendocrine Tumors in the Chinese Population
Hereditary syndromes account for roughly 5 to 10 percent of neuroendocrine tumors (NETs). However, most studies of germline mutations in NET have involved Caucasian populations. This retrospective st...
