John O'Brien @obrien-lab.bsky.social · 03/06/2026This first electrical synapse proteome reveals an evolutionarily conserved common core machinery of electrical synapses, with a number of novel proteins and insight into the full life cycle of the connexins that form electrical synapses. 010
John O'Brien @obrien-lab.bsky.social · 03/06/2026I'm happy to share that the final version of our retinal electrical synapse proteome is out. We used proximity biotinylation techniques to capture proteins associated with Cx36 in mouse retina and Cx35.1 in zebrafish retina. elifesciences.org/articles/105...elifesciences.orgUncovering the electrical synapse proteome in retinal neurons via in vivo proximity labelingA proximity labeling screen uncovers the proteome of electrical synapses in retinal neurons. 171
John O'Brien @obrien-lab.bsky.social · 26/02/2025Forget grants or papers; the happiest moment in the life of a lab is the successful defense of a PhD thesis. Congratulations Eyad Shihabeddin @eshihabeddin.bsky.social on the successful defense of your thesis after some years of work and some truly great science. 060