On real gut metagenomes from the IBD patients and healthy controls (portal.microbiome-bioactives.org) we see that the spectral energy offers better separation between condition and control samples that the standard taxonomy-only entropy.
portal.microbiome-bioactives.org
Human Microbiome Bioactives Resource (HMBR) Portal
The data portal for data generated from the Human Microbiome Bioactives Resource