🚨 New preprint alert! We uncovered a link between Parkinson’s protein α-synuclein and fat metabolism. α-syn inclusions disrupt lipid droplets and deplete TAGs during aging & MCFAs restore movement in α-synuclein worms.
👉 Targeting fat metabolism could help to combat Parkinson’s! shorturl.at/2mVG6
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Condensate-Driven Triglyceride Depletion Links α-Synuclein to Mitochondrial Dysfunction
Inclusions of α-Synuclein (αSyn) characterize multiple age-related neurodegenerative diseases, including Parkinson’s disease (PD) and Multiple System Atrophy (MSA). While interactions between αSyn and...
