Explaining those little impurities

Identify the structure using ¹H NMR spectrum

An application of the 1D TOCSY experiment that you may not know about.

Confirm the structure using ¹H and 1D NOESY data

A visual guide to HMBC, featuring must-know tips, parameter tweaks, and pitfalls to avoid when reading your NMR data.

Identify the structure using ¹H spectrum

Probing photochemistry with NMR

Identify the structure using ¹H spectrum

Rare XX'AA'MM'NN'R spin system

SpecXMaster enables chemists to determine molecular structures from experimental NMR data, returning ranked candidate structures together with a detailed elucidation report. In a head-to-head evaluation of 500 structure-elucidation cases, SpecXMaster correctly solved 77.8%, substantially outperforming leading general-purpose AI models (Gemini 3.1 Pro Preview at 44.8% and Claude Opus 4.7 at 35.0%).

From standard 1D proton spectra to low-concentration 2D experiments: sample requirements for optimal signal-to-noise.

Match the structure using ¹H spectrum

Norbornane derivative proton with strong ⁴J

Match the structure using ¹H and 1D NOESY

HALA, Heavy Atom on Light Atom effect

Match the structure using ¹H spectrum

Decoding Long-Range Couplings in Bicyclic Systems

A Metabolomic Profile of Lime Juice 🍋‍🟩📉

Match the structure using 1D NOESY experiment

Understanding 1-bond proton-carbon correlations, indirect detection, and practical interpretation for structure elucidation

Match the structure with the ¹H spectrum

Match the structure with the ¹H spectrum

A Look at Complex Spin Systems

The Two-Stereocenter Trap

Explaining COSY using Dexamethasone as a textbook example.

Time to remember the substitution test for equivalence of protons

From messy multiplets to sharp signals

Match the structure with the ¹H spectrum

Essential tips and best practices to ensure high-quality spectra and reliable structural data

ALT: may the fourth be with you is written in yellow letters on a black background

The correct answer is C! 🎯

A structured home for NMR spectroscopy insights: from fundamentals to advanced 2D techniques and unique datasets. Click to read NMR spectroscopy, by Kozytskyi Andrii, a Substack publication with hundr...