Analysis of the asexually reproducing Amazon molly Poecilia formosa and its sexually reproducing progenitors Poecilia mexicana and Poecilia latipinna reveals that it maintains a divergent mutational l...

A new heuristic ARG inference tool maps archaic hominin admixture and highlights genomic regions unique to modern humans.

Kravitz et al. develop a method to identify genes that randomly differentially express their parental alleles in human tissues and find that random allelic expression disproportionately impacts genes ...

Mammalian replication origins are fragile sites defined by poly-dA/dT stretches that are nucleosome free and devoid of the single-strand DNA-protecting protein RPA.

Asexual reproduction should be an evolutionary dead end. A study of asexual fish shows that a genetic ‘copy and paste’ helps to overcome the predicted costs of asexuality.

Asexual vertebrates are extremely rare. Here, the authors sequence the genome of the Amazon molly, an asexual fish, and find few signs of genetic degeneration but clonal polymorphism and high heterozy...

Analysis of the asexually reproducing Amazon molly Poecilia formosa and its sexually reproducing progenitors Poecilia mexicana and Poecilia latipinna reveals that it maintains a divergent mutational l...

Background The human mitochondrial genome is transcribed as long strands of RNA containing multiple genes, which require post-transcriptional cleavage and processing to release functional gene product...

Although the regulation of mitochondrial DNA (mtDNA) copy number is performed by nuclear-coded factors, very little is known about the mechanisms controlling this process. We attempted to introduce no...

Human cortical neurons undergo a protracted period of postmitotic maturation compared with those of other species. Wallace and Pollen review the cell-intrinsic and cell-extrinsic mechanisms that gover...

Pooled processing, in which cells from multiple sources are cultured or captured together, is an increasingly popular strategy for droplet-based single cell sequencing studies. This design allows effi...

ALT: a man in a green shirt is carrying a pink bag

Background The human mitochondrial genome is transcribed as long strands of RNA containing multiple genes, which require post-transcriptional cleavage and processing to release functional gene product...

Although the regulation of mitochondrial DNA (mtDNA) copy number is performed by nuclear-coded factors, very little is known about the mechanisms controlling this process. We attempted to introduce no...