Reposted by LuLu Callies
1/5: How does a presumably redundant microRNA contribute to mammalian brain development and neurodevelopmental disease? Check out our new work led by Dr. Santiago Fregoso now on bioRxiv! www.biorxiv.org/content/10.1... #Neurodev #miRNA #hydrocephalus #Genetics #bioRxiv.
biorxiv.org
Loss of miR-9-2 Causes Cerebral Hemorrhage and Hydrocephalus by Widespread Disruption of Cell-Type-Specific Neurodevelopmental Gene Networks.
MIR-9-2 is a broadly and highly expressed microRNA in the developing brain and is frequently deleted in 5q14.3 Microdeletion Syndrome, a rare but severe neurodevelopmental disorder. Despite this, litt...