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Nikki Lytle

@nikkilytle.bsky.social

549 followers 325 following 3 posts

Assistant Professor at the Medical College of Wisconsin. Tumor-microenvironment interactions and cell plasticity. Sources of joy: science, dogs, nature, comedy, sports

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Reposted by Nikki Lytle

Julie S. Di Martino, PhD. @juliesdimartino.bsky.social · 14/04/2025

🥳🚨🚨🚨Happy Monday! First publication from the lab is out! My PhD student Md Al Azim reviewed the complexity of ECM, its receptors and their role in cancer progression and therapeutic interventions! We thank Ryan Petrie for his valuable input,our reviewers and Matrix Biology for publishing our work!

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Cosimo Commisso @cosimocommisso.bsky.social · 26/03/2025

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Nikki Lytle @nikkilytle.bsky.social · 07/03/2025

@standupforscience.bsky.social Madison. Take home message = call your representatives!!

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Cosimo Commisso @cosimocommisso.bsky.social · 04/12/2024

I'm thrilled to share our latest research, published in Nature Communications. This work highlights how pancreatic cancer cells hijack cell polarity proteins to regulate macropinocytosis and tumor metabolism, shedding light on potential therapeutic vulnerabilities. www.nature.com/articles/s41...

nature.com

Cell polarity proteins promote macropinocytosis in response to metabolic stress - Nature Communications

Cancer cells rely on macropinocytosis to survive in a nutrient-deprived environment. Here, Lambies et al. identified various members of the cell polarity protein network as essential regulators of mac...

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Victor Javier @vjsanchez.bsky.social · 15/11/2024

Single-cell RNA-sequencing of human spleens reveals an IDO-1<sup>+</sup> Tolerogenic Dendritic Cell subset in pancreatic cancer patients that is absent in normal individuals. #PDAC www.sciencedirect.com/science/arti...

sciencedirect.com

Single-cell RNA-sequencing of human spleens reveals an IDO-1+ Tolerogenic Dendritic Cell subset in pancreatic cancer patients that is absent in normal individuals.

Local and systemic immunosuppression are prominent features of pancreatic cancer, rendering anti-tumor effector cells inactive and immunotherapeutic a…

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Reposted by Nikki Lytle

Victor Javier @vjsanchez.bsky.social · 15/11/2024

I’m thrilled to share the Pancreatic Cancer Starter Pack! If you want to join DM go.bsky.app/2FHVVL6

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