Excited to share our latest work in Molecular Cell: www.cell.com/molecular-ce...
We show that PRC1 condensates exclude SWI/SNF from chromatin, revealing a physical mechanism for how opposing regulators compete to control gene expression.
Huge thanks to all collaborators and mentors!
cell.com
Mutual antagonism between PRC1 condensates and SWI/SNF in chromatin regulation
Niekamp et al. show that biomolecular condensates formed by Polycomb repressive complexes
can physically restrict access of the activating remodeler SWI/SNF to chromatin. Establishing
this barrier dep...