Reposted by Nico PedroncelliBenoit Bruneau @benoitbruneau.bsky.social · 04/10/2026Happy Pluripotency Day! #Oct4 14916
Reposted by Nico PedroncelliJohn Ngo @johntngo.bsky.social · 14/10/2025Pleased to share our review on “Synthetic Mechanotransduction” — now live at Nature Reviews Bioengineering. May the force be with you! www.nature.com/articles/s44...nature.comSynthetic mechanotransduction - Nature Reviews BioengineeringCells convert mechanical forces into biochemical signals through mechanotransduction, a process which can now be synthetically engineered. In this Review, we examine engineered artificial mechanotrans... 1165
Reposted by Nico Pedroncelliernestiu.bsky.social @ernestiu.bsky.social · 30/03/2025I'm thrilled to finally share my PhD work on understanding how Ca2+ signals regulate the protruding front of the cell. It’s been an incredible journey working alongside all the collaborators. www.biorxiv.org/content/10.1...biorxiv.orgA TRPV4–dependent calcium signaling axis governs lamellipodial actin architecture to promote cell migrationCell migration is crucial for development and tissue homeostasis, while its dysregulation leads to severe pathologies. Cell migration is driven by the extension of actin–based lamellipodia protrusions... 1208
Reposted by Nico PedroncelliItai Yanai @itaiyanai.bsky.social · 24/01/2025The data is the data, so don’t do an experiment unless you’re willing to accept evidence that goes against your hypothesis. 1498