Starting off my bluesky journey by sharing my paper published this week: CD21 targeted CAR-T cells for the treatment of T-ALL.
The result of many years of work from many people. Funded by #CRUK #UKRI MRC and #GOSHCC
www.science.org/doi/10.1126/...
science.org
Preclinical development of anti-CD21 chimeric antigen receptor T cells to treat T cell acute lymphoblastic leukemia
Fratricide-resistant anti-CD21 CAR-T cells are effective in preclinical models of T cell acute lymphoblastic leukemia (T-ALL).