Our experts explain how you can secure your device and protect your data after a phishing scare

Biopharma leader Dr Liz Pease Awarded 2025 Potts Medal

PhD Project - New Magnetic Particle Imaging (MPI) methods based on complex nanocomposite particle dynamics at University of Liverpool, listed on FindAPhD.com

Merck KGaA's non-pyrophoric butyllithium in poly(α-olefin) oil make BuLi stable to air and water

A new report warns that AI poses a serious threat to children's cognitive development and emotional well-being.

Exclusive: Some scientists say many detections are most likely error, with one high-profile study called a ‘joke’

Find out more about this fully funded PhD studentship opportunity.

“We can no longer lend our credibility to an organization that has lost its integrity,” write four scientists and administrators who recently resigned from the NIH.

Grok, the chatbot created by Elon Musk’s artificial intelligence company, has produced a flood of explicit images featuring real people in recent weeks.

Guardian investigation finds AI Overviews provided inaccurate and false information when queried over blood tests

From structure confirmation to methodology improvements, making complex natural products has driven innovation in organic synthesis for decades. Nina Notman looks at its current state, with threats fr...

The BBC has seen several examples of it undressing women and putting them in sexual situations without their consent.

A factory in space has been switched on and has reached temperatures of about 1,000C.

Exclusive: British students will be able to participate in EU-wide scheme from January 2027, sources say

India and China are among the countries where knockoffs of Wegovy and Ozempic can be sold next year

We’re increasingly relying on AI tools like ChatGPT and Google Gemini to search for information online. However, they’re making basic mistakes and giving overconfident, even risky advice

AI research in question as author claims to have written over 100 papers on AI that one expert calls a ‘disaster’

Researchers uncovered 354 AI-focused accounts that had accumulated 4.5bn views in a month

Australia host England in the second Ashes Test in Brisbane - follow live scores, radio commentary, video highlights and updates.

An opportunity for an academic position as a Professor and Head of Department of Chemistry is available, as advertised on jobs.ac.uk. Apply now and explore other academic job openings.

The formation of C–N bonds by Pd-catalyzed cross-coupling is one of the most widely practiced reactions in chemical synthesis. Typical reaction conditions involve either a strong base, which limits the scope of substrates, or an insoluble, inorganic base, which complicates running reactions on a large scale. Reaction conditions for C–N couplings with a base that is both mild and soluble are needed. We report the discovery of a combination of a phosphorinane ligand (L147) and a soluble carboxylate base, potassium 2-ethylhexanoate (K-2-EH), which leads to the coupling of a wide range of base-sensitive coupling partners. To explore the enhanced substrate scope of the reaction with this base and catalyst, we evaluated the scope using representative reactants selected from published partners, using chemical descriptors and clustering to ensure their chemical diversity. These results show that the combination of this phosphorinane ligand and K-2-EH can couple primary aliphatic amines, amides, sulfonamides, and heteroaromatic nucleophiles as well as acidic secondary nitrogen nucleophiles, such as arylamines, heteroarylamines, and amides, with a range of electrophiles. A side-by-side comparison to form selected coupling products in the presence of a range of previously reported bases and ligands showed that the products that decomposed under standard reaction conditions were stable with K-2-EH as a base. Finally, models of quantitative structure–reactivity relationships, trained on ligand screening data, were developed to help reveal the structural features that engender reactivity.

Research finds OpenAI’s free chatbot fails to identify risky behaviour or challenge delusional beliefs

The chemicals would

Study finds artificial intelligence reviewers accept AI-generated scientific studies 4 out of 5 times

New material slips past skin and ferries insulin into the bloodstream

University unveils plans to establish UK's flagship AI-driven materials discovery centre

Objectives To determine the overall rate of loss of workplace teaspoons and whether attrition and displacement are correlated with the relative value of the teaspoons or type of tearoom. Design Longitudinal cohort study. Setting Research institute ...