Using frog metamorphosis, we show that spinal cord cell types diversify as locomotion shifts from swimming to walking, revealing a conserved blueprint for interneuron circuits across tetrapods. 🐟→🐸→🐭
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Multifold increase in spinal inhibitory cell types with emergence of limb movement
Frog metamorphosis reveals how spinal circuits adapt to new motor demands. Vijatovic
et al. demonstrate that the shift from tail- to limb-based locomotion coincides with
expansion and diversification ...