iiinova — where your digital self keeps evolving

Alexey Nesvizhskii @nesvilab.bsky.social · 29/05/2026

We are heading to #ASMS2026 in San Diego ! Lot’s of new research from the lab and preview of some of the new features and modules we are working on in #FragPipe. Hope to see you there.

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Alexey Nesvizhskii @nesvilab.bsky.social · 01/08/2025

Conventional proteomics searches struggle with many modifications and fully open searches may be difficult to interpret. We introduce a "detailed" mass offset search in #MSFragger boosting interpretability and localization especially in complex cases (e.g. FPOP data): www.biorxiv.org/content/10.1...

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Alexey Nesvizhskii @nesvilab.bsky.social · 30/05/2025

Wow, a record breaking number of the Nesvizhskii lab members attending #ASMS2025! 9 posters, 3 evening workshops, and one Bioinformatics Hub on #FragPipe. Plus multiple collaborative posters with other groups. See you in Baltimore! PS. Below is our recent group photo, including all those attending

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Alexey Nesvizhskii @nesvilab.bsky.social · 05/05/2025

Exciting news: We have released #FragPipe 23, and it's one of our biggest updates ever. Windows installer, support for TMT on Astral and timsTOF, TMT35, PTM site reports for DIA, improved Astral data handling in #MSFragger, improved diaTracer for diaPASEF data, better Skyline integration, and more!

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Alexey Nesvizhskii @nesvilab.bsky.social · 22/04/2025

Are you a fan of FragPipe-Analyst? Or a member of the CPTAC Proteogenomics consortium? Then you for sure know how awesome Leo (Yi Hsiao) is! And today we celebrate him receiving the Rackham Predoctoral Fellowship award from the University of Michigan. Congratulations, Leo!

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Alexey Nesvizhskii @nesvilab.bsky.social · 20/03/2025

This man played a part… ~25 years ago. This photo is from a few weeks ago at the Zurich zoo, where there was a social event as part of Ruedi’s celebration symposium. And, by the way, there is literally an elephant in the room, in the enclosure behind us.

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Alexey Nesvizhskii @nesvilab.bsky.social · 04/03/2025

One of the most significant and challenging projects of my career so far. PepCentric: a scalable computational platform utilizing novel 2-D fragment indexing for rapid peptide-centric searches, enabling proteogenomics searches against billions of spectra in seconds. www.biorxiv.org/content/10.1...

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Alexey Nesvizhskii @nesvilab.bsky.social · 17/11/2024

Ok, my first post here, to test how it works. Blank page... writers block! Resorting to an old favorite photo. Hopefully there is an active proteomics community here (and who knows, maybe that curious squirrel joined as well?)

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