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NEST Simulator

@nest-initiative.org

The NEST Simulator is an open-source high-performance tool designed for large-scale neural network simulations, offering exceptional scalability, flexibility, and interoperability. Visit nest-simulator.org to learn more! #nestsim

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NEST Simulator @nest-initiative.org · 14/09/2026

Check out EBRAINS Virtual Users’ Week - free, virtual, hands-on tutorials for EBRAINS tools including a NESTML workshop! ebrains.eu/news-and-eve...

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NEST Simulator @nest-initiative.org · 03/06/2026

We are very much looking forward to the NEST Conference 2026, which will take place in two weeks time on 16-17th of June. There is still time to register until the 14th of June! nest-simulator.org/conference

Virtual NEST Conference June 16-17th 2026

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NEST Simulator @nest-initiative.org · 10/04/2026

The abstract submission deadline for the NEST Virtual Conference 2026 has been extended to **Sunday, May 3rd**. We are inviting contributions to the conference, including talks, "posters" and workshops on specific topics. Don't miss out! nest-simulator.org/conference

NEST virtual conference 16-17th June 2026

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NEST Simulator @nest-initiative.org · 11/03/2026

Registration and submission of contributions are now open for the virtual NEST Conference 16-17 June 2026! 🎉 Please register and submit your contribution(s) via the conference website. Deadline for submission of contributions 10 April 2026 nest-simulator.org/conference.

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NEST Simulator @nest-initiative.org · 14/11/2025

Driving science, sharing and technology --- a review of the impact of a cortical microcircuit model on the fields of computational neuroscience and neuromorphic computing, a decade after its publication: doi.org/10.1093/cerc...

Impact of the PD14 model. The model of the cortical microcircuit (center) had an impact on five aspects of research (clockwise from top): conceived to provide neuroscience insight, the model became a building block of more advanced models, served as reference for the validation of mean-field theories, drove the development of methods for model sharing, and became a standard for benchmarking of neuromorphic and GPU systems.

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NEST Simulator @nest-initiative.org · 08/10/2025

Using the NEST simulator, they offer a more realistic model for neuronal networks that includes these glial cells, including a model with calcium dynamics and connectivity generation scheme for tripartite interactions.

Modeling neuron-astrocyte interactions in neural networks using distributed simulation

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NEST Simulator @nest-initiative.org · 08/10/2025

We are excited to share this paper by Jiang et al. on advancing our understanding how astrocytes play a role in brain function and plasticity! journals.plos.org/ploscompbiol...

Illustration of the biological mechanisms captured by the model framework for astrocytes

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NEST Simulator @nest-initiative.org · 09/07/2025

Do you also want to start simulating large-scale networks with dendrites? Check out these preprints from Willem Wybo and colleagues! #nestsim

Overview of the compartmental simulation toolchai

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NEST Simulator @nest-initiative.org · 03/07/2025

Very cool paper from the University of Chile investigating how local metabolic constraints influence the structure and activity of spiking neural networks (SNNs) journals.plos.org/ploscompbiol... #nestsim

Available energy and firing rate for different ATP production impairment.

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NEST Simulator @nest-initiative.org · 25/06/2025

The NEST virtual conference 2025 was another great success! Thanks to all speakers and participants for an inspiring conference! nest-simulator.org/conference

Group photo of NEST conference participants

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NEST Simulator @nest-initiative.org · 10/06/2025

We are excited to present the new paper on NESTML, a user-friendly language and toolchain for simulating SNNs with advanced plasticity rules. NESTML makes it easy for anyone to create and run models across platforms, enhancing accessibility and reproducibility in neuroscience! tinyurl.com/2x7vcc48

Rendered output from a neuron model and a synapse model example in NESTML

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NEST Simulator @nest-initiative.org · 20/05/2025

We are thrilled to share Elena Pastorelli and Pier Stanislao Paolucci’s amazing work on modeling dendritic calcium dynamics in large-scale network simulations using NEST'S multi-compartment modeling framework developed by Willem Wybo (tinyurl.com/caldyn) #nestsim

Cortical pyramidal cell and schematic of the Ca-AdEx neuron

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