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Nanion Technologies

@naniontech.bsky.social
92 followers 32 following 69 posts

For 20+ years, Nanion combines exceptional instrumentation with trusted scientific support, to accelerate successful drug development and scientific discoveries.

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Nanion Technologies @naniontech.bsky.social · 01/07/2026
Applications are now open for the first Patchlinerᵐ Research Grant! One selected recipient will receive Patchlinerᵐ in their lab for 6 months, including training, consumables, and expert support. Apply by Sept. 25, 2026: ow.ly/Y9MI50ZiLh4 #patchclamp #ionchannels
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Nanion Technologies @naniontech.bsky.social · 23/04/2026
What does it look like to measure ion channels in lysosomes with automated patch clamp? See how native lysosomes can be recorded on the SyncroPatch 384 using ready-to-use Lyso-preps from ORIA Bioscience. #Lysosomes #Electrophysiology #DrugDiscovery
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Nanion Technologies @naniontech.bsky.social · 27/03/2026
What connects ion channels to disease? At MPS 2026, speakers incl. Jun Chen, David K. Jones & Franck Kalume will present work on channel function, regulation & disease. Topics include hERG, SCN1A & lysosome ion channels. April 14–15 | Napa ow.ly/M8Ix50YyBRO #MPS2026 #MembranePhysiology
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Nanion Technologies @naniontech.bsky.social · 26/03/2026
How do changes in ion channel and transporter function translate into neurological disease? Join the Neuroscience Symposium 2026 to explore this across neuroscience & electrophysiology. 📅 May 20, 2026 | Virtual Free registration: ow.ly/aUV250Yz6iY #Neuroscience #Electrophysiology
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Nanion Technologies @naniontech.bsky.social · 25/03/2026
MPS 2026 takes place April 14–15 in Napa Valley Key speakers include Ardem Patapoutian and Lori Isom. The program covers ion channels, transporters, membrane proteins, electrophysiology, and translational research. Register: ow.ly/M8Ix50YyBRO #MPS2026
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Nanion Technologies @naniontech.bsky.social · 24/02/2026
MPS 2026 agenda highlights The program covers ion channel biology, mechanotransduction, membrane structure, transporters, and translational physiology. April 14–15, 2026 | Napa Valley See agenda and more info here: ow.ly/O4Or50YkU8q
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Nanion Technologies @naniontech.bsky.social · 22/02/2026
Booth #528 at #BPS2026 is open. We’re introducing two new additions to our APC portfolio. Built on 20+ years of experience. Designed for today’s electrophysiology challenges. Two new paths to patch clamp. One shared principle: high-quality data without compromise. Which path fits your research?
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Nanion Technologies @naniontech.bsky.social · 19/02/2026
Over the last 20 years, Patchliner has supported a wide range of #electrophysiology research including #APC in academia, #cardiacsafety and CiPA initiatives, #drugdiscovery workflows in pharma and more. These applications shaped how the Patchliner has evolved. Full reveal at #BPS2026.
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Nanion Technologies @naniontech.bsky.social · 17/02/2026
Twenty years of experience rarely lead to small changes. This is just a glimpse of what we’ve been working on, shaped by: ✔️ Years of feedback ✔️ Evolving experimental demands ✔️ Changing expectations around data quality and scale in electrophysiology Full reveal at #BPS2026. #PatchClamp #20years
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Nanion Technologies @naniontech.bsky.social · 13/02/2026
𝗔𝗹𝘄𝗮𝘆𝘀 𝗮 𝗽𝗹𝗲𝗮𝘀𝘂𝗿𝗲 𝘁𝗼 𝘄𝗲𝗹𝗰𝗼𝗺𝗲 𝘁𝗵𝗲 𝗽𝗲𝗼𝗽𝗹𝗲 𝗱𝗿𝗶𝘃𝗶𝗻𝗴 𝗴𝗿𝗲𝗮𝘁 𝘀𝗰𝗶𝗲𝗻𝗰𝗲 𝘁𝗼 𝗡𝗮𝗻𝗶𝗼𝗻 We were happy to host Glenn and his team for early SyncroPatch 384 training. Hands-on sessions, first preliminary data, and great discussions, excited to see what comes next. #SyncroPatch384 #Electrophysiology
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Nanion Technologies @naniontech.bsky.social · 11/02/2026
Join the discussion at our #BPS2026 posters We’ll be sharing and discussing data across ion channels, transporters & membrane biophysics. And while you’re there, stop by Booth #528, we have special news to share 👀 About the posters: ow.ly/9rkT50Y7vkQ #BPS2026 #Posters #APC #Biophysics
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Nanion Technologies @naniontech.bsky.social · 09/02/2026
Looking back at MPS 2025 in Napa Valley A meeting report published in Bioelectricity documents the scientific scope and discussions of the Membrane Physiology Symposium. These principles continue to guide MPS 2026, returning to Napa Valley in April 14-15, 2026. ow.ly/B14Q50YbxJJ
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Nanion Technologies @naniontech.bsky.social · 05/02/2026
Live transporter recordings at #BPS2026 Real-time SSME on the SURFE²R N1, measured live on site. Limited spots available, register to attend the live demos. ow.ly/1svz50Y9g3R #BPS2026 #Transporters #TMEM175 #SSME #Lysosomes #Electrophysiology #Collaboration
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Nanion Technologies @naniontech.bsky.social · 02/02/2026
Join our exhibitor presentation at #BPS2026 🔬 We’ll be discussing electrophysiological tools advancing ion channel & transporter drug discovery. Looking forward to the discussion with the community. Learn about our activities at BPS: ow.ly/3JYw50Y7uuP
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Nanion Technologies @naniontech.bsky.social · 28/01/2026
We’re hosting SURFE²R N1 live demo sessions at #BPS2026 𝗡𝗼𝘁 𝗽𝗿𝗲-𝗿𝗲𝗰𝗼𝗿𝗱𝗲𝗱. 𝗡𝗼𝘁 𝘀𝗶𝗺𝘂𝗹𝗮𝘁𝗲𝗱. 𝗥𝗲𝗰𝗼𝗿𝗱𝗲𝗱 𝗹𝗶𝘃𝗲 𝗮𝘁 𝗕𝗣𝗦. 📍 Moscone Center, Esplanade Room 158 📅 Two live sessions: Sunday, Feb 22 | 12:30–2:00 PM Monday, Feb 23 | 12:30–2:00 PM Register here: ow.ly/B00250Y4SAi
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Nanion Technologies @naniontech.bsky.social · 26/01/2026
Attending WSCC26 in Grindelwald? Let’s connect. Feb 4–6, the global sodium channel community meets in person. Our Senior Scientist Markus Rapedius will be on site and presenting a poster on APC-based analysis of excitability in ALS iPSC-derived motor neurons (with Axol). #WSCC26 #SodiumChannels
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Nanion Technologies @naniontech.bsky.social · 21/01/2026
We’re pleased to announce Prof. Glenn King and his team at the Institute for Molecular Bioscience, The University of Queensland, as winners of the 2025 SyncroPatch 384 Research Grant. Congratulations to Prof. King and team 👏 Learn more: ow.ly/NQVn50XZLzX #IonChannels #Grant #APC
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Nanion Technologies @naniontech.bsky.social · 20/01/2026
We’re pleased to announce Medha Pathak (UC Irvine, US) as a winner of the 2025 SyncroPatch 384 Research Grant, together with co-PIs Francesco Tombola, Jerome Lacroix, and Lyna Luo. Congratulations to the entire team 👏 More details here: ow.ly/K3Pf50XZLic #IonChannels #APC #Grant
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Nanion Technologies @naniontech.bsky.social · 19/01/2026
𝗙𝗲𝗯𝗿𝘂𝗮𝗿𝘆 = 𝗕𝗶𝗼𝗽𝗵𝘆𝘀𝗶𝗰𝗮𝗹 𝗦𝗼𝗰𝗶𝗲𝘁𝘆 𝗺𝗼𝗻𝘁𝗵 🔬 We’re heading to #BPS2026 with a full program of activities. Find us at Booth #528 for live demos and discussions on ion channels, transporters & biophysics. Will you be there? ow.ly/79Yi50XZBkg #Events #APC #Biophysics
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Nanion Technologies @naniontech.bsky.social · 15/01/2026
𝟮𝟰 𝘆𝗲𝗮𝗿𝘀 𝗼𝗳 𝗡𝗮𝗻𝗶𝗼𝗻, 𝗱𝗿𝗶𝘃𝗲𝗻 𝗯𝘆 𝘀𝗰𝗶𝗲𝗻𝗰𝗲 𝗮𝗻𝗱 𝗰𝗼𝗹𝗹𝗮𝗯𝗼𝗿𝗮𝘁𝗶𝗼𝗻 🎉 As we start 2026, we’re grateful for a year shaped by community, exchange, and shared progress. We’ve captured key moments from 2025 in our Annual Review. Read more 👉 ow.ly/VmJC50XXc4z #TeamNanion #Anniversary
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Nanion Technologies @naniontech.bsky.social · 14/01/2026
Why early safety assessment needs a new approach Animal models and simple assays often miss human-specific risk. New Approach Methodologies (NAMs) combine human-relevant biology with scalable in vitro tools to enable earlier, more predictive safety insight. Read more: ow.ly/Bm5650XWCKU
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Nanion Technologies @naniontech.bsky.social · 14/01/2026
Renal ion channels have been linked to kidney disease for decades, yet they remain underexplored as drug targets. This blog connects basic channel biology with ongoing drug discovery efforts, from APOL1 to TRPC and PKD. Read the full blog: ow.ly/lJjg50XW5Eb #APC #IonChannels
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Nanion Technologies @naniontech.bsky.social · 23/09/2025
𝗔𝗽𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻𝘀 𝗮𝗿𝗲 𝗼𝗽𝗲𝗻 𝗳𝗼𝗿 𝘁𝗵𝗲 𝗦𝘆𝗻𝗰𝗿𝗼𝗣𝗮𝘁𝗰𝗵 𝟯𝟴𝟰 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗚𝗿𝗮𝗻𝘁! Get 9 months with the system, consumables, and full support to accelerate your research. Deadline: Oct 31. Apply now! ow.ly/9gx050X0OOW #APC #IonChannels #Electrophysiology
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SyncroPatch 384 Research Grant - Nanion Technologies
In 2025, we are offering the chance for you to win a SyncroPatch 384 for 9 months.
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Nanion Technologies @naniontech.bsky.social · 14/08/2025
Reduce variability in NaV studies with adaptive voltage clamp on the SyncroPatch 384. Tailor Vhalf per well, gain better IC50 precision, and study state-dependent effects with confidence. Check out the flyer to see how it works! ow.ly/8QMU50WFXei #APC #IonChannels #NaV #Electrophysiology
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Nanion Technologies @naniontech.bsky.social · 10/06/2025
How do CaV1.2 mutations drive both arrhythmias and neuro symptoms in Timothy syndrome? Join Ivy Dick on June 12 to learn how high-throughput patch clamp reveals mutation-specific gating changes tied to clinical outcomes. 📍https://ow.ly/PxZY50W72H7 #PatchClamp #Channelopathies #IonChannels
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Nanion Technologies @naniontech.bsky.social · 15/05/2025
In a recent study, researchers developed and validated an automated #patchclamp ( #APC ) approach using the SyncroPatch 384 platform to detect #ENaC - mediated currents in a high-throughput format. Read more here: www.nanion.de/news/automat...
nanion.de
Automated patch clamp for ENaC drug discovery - Nanion Technologies
The epithelial sodium channel (ENaC) plays a central role in regulating sodium balance, blood pressure, and pulmonary fluid clearance. Despite its clinical relevance, progress in discovering new ENaC-...
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Nanion Technologies @naniontech.bsky.social · 05/05/2025
Most cardiac gene variants are still classed as “uncertain.” Join us on Thursday to learn how APC is helping reclassify VUS and improve clinical decisions. 🗓️ May 8 | 16:00–17:00 CEST 🔗 ow.ly/RQfB50VFl93 Hope to see you there! #CardiacGenetics #APC #VUS #LQTS #Brugada
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Nanion Technologies @naniontech.bsky.social · 28/04/2025
How do beta-lactam antibiotics get into our cells, and how can we use that to design better drugs? Join our webinar on May 14 to explore new insights into PepT2, drug uptake, and delivery. 🔗 Register: ow.ly/1mCL50Vo2j8 #PepT2 #DrugDesign #CryoEM #Webinar
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Nanion Technologies @naniontech.bsky.social · 15/04/2025
Why is NHE9 active in endosomes but silent at the membrane? A new Nature Communications study reveals a lipid switch: PI(3,5)P₂ stabilizes NHE9’s dimer only in endosomes. 🔗Read the full article to find out more: ow.ly/zrsR50VAAZW #MembraneTransport #CryoEM #SSME
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Nanion Technologies @naniontech.bsky.social · 14/04/2025
Join us in exactly one month for our next transporters webinar! Dr. Joanne Parker (University of Oxford) will present research insights on PepT2 (SLC15A2), a key player in beta-lactam antibiotic transport. 📅 May 14, 2025 | 🕓 16:00–17:00 CEST 🔗 Register here: ow.ly/1mCL50Vo2j8 #MembraneTransport
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Webinar: Understanding antibiotic uptake via PepT2 - Nanion Technologies
Date: May 14, 2025 Time: 16:00 – 17:00 CEST Location: Online via Zoom
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Nanion Technologies @naniontech.bsky.social · 11/04/2025
𝗖𝗮𝗻 𝘄𝗲 𝗶𝗺𝗽𝗿𝗼𝘃𝗲 𝘁𝗵𝗲 𝘄𝗮𝘆 𝘄𝗲 𝗶𝗻𝘁𝗲𝗿𝗽𝗿𝗲𝘁 𝗰𝗮𝗿𝗱𝗶𝗮𝗰 𝗴𝗲𝗻𝗲 𝘃𝗮𝗿𝗶𝗮𝗻𝘁𝘀? Join Dr. Chai Ng (Victor Chang Cardiac Research Institute) on May 8 to explore APC’s role in variant classification for inherited arrhythmias. 🔗 ow.ly/XrnO50VymFI #Webinar @chaiannng.bsky.social @victorchang.edu.au
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Nanion Technologies @naniontech.bsky.social · 10/04/2025
iPSC-CMs are powerful, but their immaturity limits their predictive value. A recent study from TU Dresden shows how combining metabolic medium, nanopatterning, and electrostimulation significantly enhances structural and electrophysiological maturation. 🔗 lnkd.in/dipXpmyN #Cardiac #iPSC #APC
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Nanion Technologies @naniontech.bsky.social · 09/04/2025
TRPV3 is a temperature-sensitive, ligand-gated ion channel known for its role in warmth perception. It can be activated by heat (~ 38˚C) or by 2-APB, and we have explored both activation modes using APC with temp control. Read the app note: ow.ly/YMp850R6hwG #TRPV3 #IonChannels #Electrophysiology
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Nanion Technologies @naniontech.bsky.social · 04/04/2025
Cryo-EM reveals how cholesterol and sphingomyelin shape the structure and stability of a membrane pore formed by the toxin Fav. Electrophysiology with the Orbit Mini confirms cholesterol reduces current noise. 🔗 Read more in the paper: ow.ly/sPmJ50VusCf #CryoEM #MembraneBiophysics #Orbitmini
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Nanion Technologies @naniontech.bsky.social · 02/04/2025
𝗛𝗼𝘄 𝗱𝗼 𝗯𝗲𝘁𝗮-𝗹𝗮𝗰𝘁𝗮𝗺 𝗮𝗻𝘁𝗶𝗯𝗶𝗼𝘁𝗶𝗰𝘀 𝗲𝗻𝘁𝗲𝗿 𝘁𝗵𝗲 𝗯𝗼𝗱𝘆? And why does it matter for drug design? Join us on May 14 as Joanne Parker (University of Oxford) presents new insights into the structure and function of PepT2, a key transporter in beta-lactam pharmacokinetics. ow.ly/1mCL50Vo2j8 #MembraneTransport
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Nanion Technologies @naniontech.bsky.social · 25/03/2025
Understanding cardiac function needs more than one readout This flyer shows how combining electrophysiology, contractility & viability data offers deeper insights into drug effects & disease models. Discover more in the flyer: ow.ly/LGRs50VnV0o #CardiacResearch #iPSC
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Nanion Technologies @naniontech.bsky.social · 14/03/2025
Studying pore-forming toxins? At Nanion, we provide advanced tools - parallel bilayer recording stations, GUVs, and planar patch clamp systems - to help researchers get a clearer picture of how these toxins work. Learn more: www.linkedin.com/feed/update/... #PFT #toxins #electrophysiology
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Nanion Technologies @naniontech.bsky.social · 14/03/2025
Working with toxins & ion channels? Testing multiple fractions and screening channels with limited samples is tough. That’s why more scientists are turning to automated patch clamp for faster, reliable results. Curious? Learn more: www.nanion.de/application-... #ionchannels #toxins #patchclamp
nanion.de
Toxins and venom-derived peptides - Nanion Technologies
Ion channels are complex proteins that control the flow of ions across cell and organelle membranes. Ion channels are present in every cell type and thereby control neuronal excitability, cardiac, ske...
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Nanion Technologies @naniontech.bsky.social · 13/03/2025
𝗝𝗼𝗶𝗻 𝘂𝘀 𝗮𝘁 𝘁𝗵𝗲 𝗠𝗲𝗺𝗯𝗿𝗮𝗻𝗲 𝗣𝗵𝘆𝘀𝗶𝗼𝗹𝗼𝗴𝘆 𝗦𝘆𝗺𝗽𝗼𝘀𝗶𝘂𝗺! From ion channels to drug discovery—discover what’s next in electrophysiology. Connect with leading experts in Napa Valley! 📅 Apr 30–May 1 𝗟𝗶𝗺𝗶𝘁𝗲𝗱-𝗧𝗶𝗺𝗲 𝗢𝗳𝗳𝗲𝗿: 𝟭𝟱% 𝗢𝗳𝗳 𝗧𝗶𝗰𝗸𝗲𝘁𝘀 Register now 🔗 ow.ly/SmfE50VgoHz #MPS25 #MembranePhysiology
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Nanion Technologies @naniontech.bsky.social · 12/03/2025
Venom-derived toxins offer unique precision in ion channel research. We tested Huwentoxin-IV, TTX, GsMTx4 & α-Conotoxin MI on NaV1.7 and nAChR to explore their blocking effects. Want to learn more? Read more in the full study: ow.ly/bKoG50Vgpy3 #IonChannels #DrugDiscovery #APC
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Nanion Technologies @naniontech.bsky.social · 06/03/2025
In a pioneering study, Achouba et al. successfully integrated photoswitch technology into a complex, disulfide-rich peptide ChTx while retaining high nanomolar potency for ion channels. Read more here: www.nanion.de/news/optical... #ionchannels #optogenetics #patchclamp #APC #venom #toxins
nanion.de
Optical control of Kv1.2 channels via azobenzene-modified charybdotoxin - Nanion Technologies
Animal venom peptides like charybdotoxin (ChTx) are known for their high specificity and potency as potassium channel blockers, making them valuable tools in ion channel research. However, achieving p...
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Nanion Technologies @naniontech.bsky.social · 05/03/2025
𝗛𝗲𝗮𝗱𝗶𝗻𝗴 𝘁𝗼 𝗡𝗲𝘅𝘁𝗚𝗲𝗻 𝗕𝗶𝗼𝗺𝗲𝗱 𝟮𝟬𝟮𝟱? 𝗟𝗲𝘁’𝘀 𝗖𝗼𝗻𝗻𝗲𝗰𝘁! Meet us at Booth #60 to see AtlaZ in action—now GxP compliant! Get real-time, label-free insights into cell activity & viability and explore its impact on drug discovery & immuno-oncology. 🔗 ow.ly/nl0s50Vafhh #NextGenBiomed #GxP #AtlaZ
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Nanion Technologies @naniontech.bsky.social · 03/03/2025
𝗝𝗼𝗶𝗻 𝘂𝘀 𝗮𝘁 𝘁𝗵𝗲 𝗖𝗮𝗿𝗱𝗶𝗮𝗰 𝗦𝗮𝗳𝗲𝘁𝘆 𝗦𝘆𝗺𝗽𝗼𝘀𝗶𝘂𝗺 𝟮𝟬𝟮𝟱! 📅 May 21, 2025 | 🌍 Virtual The symposium will bring together experts to discuss the latest advancements in safety pharmacology, cardiac physiology, and electrophysiology. 🔗 Learn more and register here 👉 ow.ly/VvWl50TPkbR #CardiacSafety #Pharmacology
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Nanion Technologies @naniontech.bsky.social · 27/02/2025
AtlaZ now offers 𝗙𝗗𝗔 𝟮𝟭 𝗖𝗙𝗥 𝗣𝗮𝗿𝘁 𝟭𝟭 𝗰𝗼𝗺𝗽𝗹𝗶𝗮𝗻𝗰𝗲, ensuring secure, traceable, and audit-ready data for regulated research. ✅ Secure access & user tracking ✅ Audit trails & data integrity ✅ Compliance made simple 📄 Learn more: ow.ly/Oaln50V6Qk3 #CellAnalytics #GxPCompliance #21CFRPart11
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Nanion Technologies @naniontech.bsky.social · 26/02/2025
Our latest case study highlights how Frédéric Becq from the University of Poitiers uses automated patch-clamp technology to deepen our understanding of CFTR function and its interactions with drugs. Read more here: www.nanion.de/wp-content/u... #ionchannels #CFTR
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Nanion Technologies @naniontech.bsky.social · 25/02/2025
𝗛𝗼𝘄 𝗰𝗵𝗮𝗻𝗻𝗲𝗹𝗼𝗽𝗮𝘁𝗵𝗶𝗲𝘀 𝗮𝗿𝗲 𝗮𝗱𝘃𝗮𝗻𝗰𝗶𝗻𝗴 𝗱𝗿𝘂𝗴 𝗱𝗶𝘀𝗰𝗼𝘃𝗲𝗿𝘆? 🧬 Mutations in ion channels are linked to 1,300+ genetic disorders, many driving rare diseases. Understanding these mutations enables faster, more precise profiling, crucial for targeted therapies. 🔗 ow.ly/C0ST50V60SB #RareDiseases #DrugDiscovery
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Nanion Technologies @naniontech.bsky.social · 19/02/2025
The INNOVATION consortium is shaping the next generation of researchers! At our recent meeting, students gained hands-on training while project leaders planned the next steps. Exciting progress in RBC ion channel research. Looking forward to future breakthroughs! 🚀 #IonChannels #Electrophysiology
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Nanion Technologies @naniontech.bsky.social · 17/02/2025
Silent Molecular Translocation Some molecules move through nanopores without altering ionic currents, remaining invisible to traditional methods. The Orbit mini captures these silent events using optical + electrical recordings, unlocking new insights in biophysics & diagnostics ow.ly/HLFM50V16oS
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Nanion Technologies @naniontech.bsky.social · 14/02/2025
A recent study provides detailed structural insights into how potassium-selective channelrhodopsins (KCRs) function. Read here: www.nanion.de/news/light-g... #ionchannels #optogenetics #patchclamp #APC
nanion.de
Light-gating of potassium-selective channelrhodopsin - Nanion Technologies
Channelrhodopsins (ChRs) are light-sensitive ion channels widely used in optogenetics to precisely control neuronal and cardiac activity. While most ChRs conduct cations non-selectively, a specialized...
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Nanion Technologies @naniontech.bsky.social · 14/02/2025
The Biophysical Society Meeting, starts today! Check out our activities: 🔹 Ion channel drug discovery at our Satellite Meeting - Today! 🔹 Booth #509 – Live demos & latest innovations 🔹 Feb 17, 11:30 AM – Join us at our Exhibitor presentation 🔹 Don´t miss out on our Posters lnkd.in/dPKd-Q2B #BPS25
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