Excited to share our work, now online in Blood Cancer Discovery! We dissected noncoding variants influencing clonal hematopoiesis using MPRA.
aacrjournals.org/bloodcancerd...
Congrats to Trieu Nguyen, Jessica Jeejan and the team. Thanks to @tewhey.bsky.social and his team for the collaboration!
aacrjournals.org
Germline noncoding risk variants influence clonal hematopoiesis through altered hematopoietic enhancer activity
Abstract. Clonal hematopoiesis of indeterminate potential (CHIP) is a precursor condition characterized by the expansion of mutant hematopoietic stem and progenitor cell (HSPC) clones that increases t...