The complex effects of biomaterial and animal characteristics on wound healing and metastatic tumor formation in bone are revealed with single-cell RNA-seq in my most recent PhD work in #Biomaterials with @madhavmantri.bsky.social @fischbachlab.bsky.social & Iwijn De Vlaminck #cornellbme t.ly/WAjXZ
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Bone mineral density affects tumor growth by shaping microenvironmental heterogeneity
Breast cancer bone metastasis is a major cause of mortality in patients with advanced breast cancer. Although decreased mineral density is a known ris…