mvazquezlevin.bsky.social @mvazquezlevin.bsky.social · 27/03/2026While neonatal outcomes were reported as unaffected, the study lacks detailed and long-term follow-up of offspring, which prevents robust conclusions about the broader implications for child health. #ESHREjc 052
mvazquezlevin.bsky.social @mvazquezlevin.bsky.social · 27/03/2026Indeed, although propensity score matching was used to control for key confounders, residual confounding cannot be excluded, particularly regarding female-related factors that strongly influence IVF/ICSI outcomes, such as oocyte quality and endometrial receptivity. #ESHREjc 031
mvazquezlevin.bsky.social @mvazquezlevin.bsky.social · 27/03/2026These findings challenge the long-standing perception of ICSI as a complete equalizer of male factor infertility. Instead, they reinforce the biological relevance of sperm-derived contributions to early embryogenesis, likely reflecting underlying genomic and epigenetic integrity. #ESHREjc 144
mvazquezlevin.bsky.social @mvazquezlevin.bsky.social · 27/03/2026The data compellingly demonstrate that severe MF infertility—particularly severe OA (in paper OAT) and NOA—is not fully mitigated by ICSI. Rather, it remains significantly associated with impaired fertilization, reduced embryo developmental competence, and lower cumulative live birth rates. #ESHREjc 144
mvazquezlevin.bsky.social @mvazquezlevin.bsky.social · 27/03/2026#ESHREjc Hello Everyone! One of the most persistent assumptions in ART is that ICSI has effectively overcome male infertility impact. But has it? This study addresses whether male infertility is merely a barrier to fertilization or a determinant of reproductive success across the entire ART. 163
