Reposted by Mike Thompson, MD, PhD, FASCO
Is liquid biopsy useful in bone-only metastatic #breastcancer?
Surprise!
✅Pts w bone-only disease are just as likely to have detectable ctDNA
✅ctDNA tumor fraction remains prognostic in bone-only setting
link.springer.com/article/10.1...
@osucccjames.bsky.social
link.springer.com
Utility of plasma circulating DNA tumor fraction in bone-only metastatic breast cancer: a real-world outcomes study - Breast Cancer Research and Treatment
Purpose Bone metastases develop in 50–70% of patients with metastatic breast cancer (MBC), with around one-third having bone as only site of distant disease (bone-only [BO]). Standard imaging is frequ...