In this Review, van Sinderen and colleagues explore how bifidobacteria evolved as an important human gut symbiont, highlighting genomic adaptations, metabolic versatility, ecological interactions and ...

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Nature Microbiology, Published online: 27 July 2026; doi:10.1038/s41564-026-02424-1Structural and biochemical follow-up of a serendipitous discovery reveals that Akkermansia muciniphila carbohydrate sulfatases are uniquely adapted to digest colonic mucins in collaboration with other members of gut microbiota.