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Francesco Carli

@mrfcharles.bsky.social
76 followers 655 following 12 posts

PhD student in Artificial Intelligence @Scuola Normale Superiore, Pisa, Italy. Moving to EMBL-EBI, Cambridge, UK from 2025

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Francesco Carli @mrfcharles.bsky.social · 16/02/2025
🎉Our latest paper is out in Nature Communications: "Learning and Actioning General Principles of Cancer Cell Drug Sensitivity" 📄🔍 We present an interpretable ML pipeline that predicts drug sensitivity in cancer cell lines, leveraging large-scale pharmacogenomics datasets for actionable insights. 🧬💊
nature.com
Learning and actioning general principles of cancer cell drug sensitivity - Nature Communications
Potential anti-tumor therapies remain to be discovered in cancer cell line high-throughput screening datasets. Here, the authors develop a machine learning approach to infer cancer cell drug sensitivi...
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Francesco Carli @mrfcharles.bsky.social · 21/11/2024
🧵 A huge thanks to the creators of umap-learn for their work on UMAP! While trying to get parametric UMAP to work for my project, I ran into some challenges, so I decided to dive in and build my own PyTorch-based version from scratch. You can check it up here github.com/mr-fcharles/...
github.com
GitHub - mr-fcharles/parametric_umap: A PyTorch implementation of Parametric UMAP (Uniform Manifold Approximation and Projection) for learning low-dimensional parametric embeddings of high-dimensional...
A PyTorch implementation of Parametric UMAP (Uniform Manifold Approximation and Projection) for learning low-dimensional parametric embeddings of high-dimensional data - mr-fcharles/parametric_umap
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