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Mary Lyon Centre at MRC Harwell

@mrcharwell.bsky.social

215 followers 259 following 296 posts

The UK’s national facility for mouse genetics and the use of mouse models for the pre-clinical study of human disease

Posts Replies Media

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 08/10/2026

Still using Sanger for validation of genome engineering? Discover how long read sequencing transforms genome editing and gene targeting workflows. Learn from real datasets, sharpen your analysis skills for increased confidence in the quality of cellular and animal models.

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Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 07/10/2026

#Training: Join us in October for our 2-day Mouse Necropsy and Tissue Processing course to learn how to perform a basic standard mouse necropsy, as well as how to treat collected tissues in preparation for histological processing and embedding:

Mouse Necropsy and Tissue Processing | Mary Lyon Centre

Get the best training in our state of the art training facility built to provide courses in genetics, pathology, transgenics and more!

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Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 06/10/2026

#Training: Our Practical Laboratory Skills course covers basic theoretical and practical lab skills, including use of standard equipment, such as biosafety cabinets, centrifuges, pipettes, and balances We have a couple more dates coming up, including 18th November:

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Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 29/09/2026

We're at BioForward at the brand new CO:LABS Building on Harwell Campus today! If you're there, stop by our stand to say hi and hear about how we can support your work! #BioForward26

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Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 28/09/2026

We're exhibiting at BioForward 2026 tomorrow on Harwell Campus! Looking forward to meeting founders, R&D teams and growing life sciences companies from across the sector. Come and say hello if you're attending! 🔗 Sign up here: lnkd.in/eXmhgRby hashtag#BioForward26

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 24/09/2026

We are #hiring a Mechanical Facilities Technician to join our Engineering and Estates team, where they will undertake mechanical installation, maintenance, and fault-finding on a variety of piped systems and building services, such as heating/cooling, HVAC, and steam. Apply by 27th September

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Mechanical Facilities Technician

Mary Lyon Centre at MRC Harwell | Open Ended | Salary: £33,419 - £37,582 | MRC Band 5 S1| Closing date: 27 September 2026

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Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 15/09/2026

We are #hiring a Mechanical Facilities Technician to join our Engineering and Estates team, where they will undertake mechanical installation, maintenance, and fault-finding on a variety of piped systems and building services, such as heating/cooling, HVAC, and steam. Apply by 27th September

fa-evzn-saasfaukgovprod1.fa.ocs.oraclecloud.com

Mechanical Facilities Technician

Mary Lyon Centre at MRC Harwell | Open Ended | Salary: £33,419 - £37,582 | MRC Band 5 S1| Closing date: 27 September 2026

000

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 10/09/2026

#Training: Book your place on our Mouse Necropsy practical training course to learn how to perform a basic standard mouse necropsy and describe gross observations made during this process This course is running again in November. Book now!

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Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 09/09/2026

Our flagship training course, Mouse Models for Human Disease, is running again in February. Designed for researchers with a basic understanding of mouse genetics, it provides practical guidance on experimental design, model selection, and breeding strategies. Find out more and book now:

Mouse Models for Human Disease Workshop | Mary Lyon Centre

Get the best training in our state of the art training facility built to provide courses in genetics, pathology, transgenics and more!

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Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 08/09/2026

#Training: Laboratory management is a subject that is often learned on the job, with limited training opportunities for those new to the role. This course is aimed at both researchers new to management and managers new to the lab setting.

Best Practices in Laboratory Management | Mary Lyon Centre

Get the best training in our state of the art training facility built to provide courses in genetics, pathology, transgenics and more!

000

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 03/09/2026

Still using Sanger for validation of genome engineering? Discover how long read sequencing transforms genome editing and gene targeting workflows. Learn from real datasets, sharpen your analysis skills for increased confidence in the quality of cellular and animal models.

Genome Engineering and Validation by Long Read Sequencing | Mary Lyon Centre

Get the best training in our state of the art training facility built to provide courses in genetics, pathology, transgenics and more!

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 02/09/2026

We are #hiring a Mechanical Facilities Technician to join our Engineering and Estates team, where they will undertake mechanical installation, maintenance, and fault-finding on a variety of piped systems and building services, such as heating/cooling, HVAC, and steam. Apply by 27th September

fa-evzn-saasfaukgovprod1.fa.ocs.oraclecloud.com

Mechanical Facilities Technician

Mary Lyon Centre at MRC Harwell | Open Ended | Salary: £33,419 - £37,582 | MRC Band 5 S1| Closing date: 27 September 2026

000

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 01/09/2026

#Training: Our Laboratory Skills for Animal Technicians course is for #technicians who would like to develop their lab skills, including processing blood samples, dose calculations, and use of standard equipment. Join us in October:

Laboratory Skills for Animal Technicians | Mary Lyon Centre

Get the best training in our state of the art training facility built to provide courses in genetics, pathology, transgenics and more!

000

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 27/08/2026

A mouse line generated by the MLC’s Genome Editing Mice for Medicine programme has helped researchers demonstrate proof of concept for an RNA-directed therapy targeting a rare neurodegenerative disorder that currently has no treatment. The findings were recently published in Brain. Read more

Using a GEMM programme mouse to test the potential for RNA-directed therapy to treat a rare neurodegenerative disease | Mary Lyon Centre

Get the best training in our state of the art training facility built to provide courses in genetics, pathology, transgenics and more!

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Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 20/08/2026

Still using Sanger for validation of genome engineering? Discover how long read sequencing transforms genome editing and gene targeting workflows. Learn from real datasets, sharpen your analysis skills for increased confidence in the quality of cellular and animal models.

000

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 18/08/2026

#Training: Book your place on our Mouse Necropsy practical training course to learn how to perform a basic standard mouse necropsy and describe gross observations made during this process This course is running again in November. Book now!

Mouse Necropsy | Mary Lyon Centre

Get the best training in our state of the art training facility built to provide courses in genetics, pathology, transgenics and more!

000

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 13/08/2026

#Training: Our Laboratory Skills for Animal Technicians course is for #technicians who would like to develop their lab skills, including processing blood samples, dose calculations, and use of standard equipment. Join us in October:

000

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 12/08/2026

#Training: Laboratory management is a subject that is often learned on the job, with limited training opportunities for those new to the role. This course is aimed at both researchers new to management and managers new to the lab setting.

Best Practices in Laboratory Management | Mary Lyon Centre

Get the best training in our state of the art training facility built to provide courses in genetics, pathology, transgenics and more!

000

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 11/08/2026

#Training: Cryopreservation allows long-term storage of embryos and sperm, providing a convenient way to preserve, protect, and transport your mouse line, as well as removing the need for continued animal breeding. Book your place on our Cryopreservation course now!

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 06/08/2026

#Training: Basic lab skills are key to high quality, reproducible research. Our Practical Laboratory Skills course covers a range of basic skills, including use of standard equipment, such as centrifuges, balances, pipettes, and fume hoods We have multiple dates scheduled, including 16th September:

Practical Laboratory Skills | Mary Lyon Centre

Get the best training in our state of the art training facility built to provide courses in genetics, pathology, transgenics and more!

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 05/08/2026

#Training: Join us in October for our 2-day Mouse Necropsy and Tissue Processing course to learn how to perform a basic standard mouse necropsy, as well as how to treat collected tissues in preparation for histological processing and embedding:

000

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 04/08/2026

Want to understand genetic drift and how to maintain integrity in both simple and complex genetically altered mouse lines? Book your place on our 3-day Mouse Genetics and Colony Management for Researchers course and join us in October!

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 29/07/2026

#Training: Our Practical Laboratory Skills course covers basic theoretical and practical lab skills, including use of standard equipment, such as biosafety cabinets, centrifuges, pipettes, and balances We have multiple dates through the year, including 18th November:

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 23/07/2026

#Training: Cryopreservation allows long-term storage of embryos and sperm, providing a convenient way to preserve, protect, and transport your mouse line, as well as removing the need for continued animal breeding. Book your place on our Cryopreservation course now!

Mouse Embryo and Spermatozoa Cryopreservation Course | Mary Lyon Centre

Get the best training in our state of the art training facility built to provide courses in genetics, pathology, transgenics and more!

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 22/07/2026

Still using Sanger for validation of genome engineering? Discover how long read sequencing transforms genome editing and gene targeting workflows. Learn from real datasets, sharpen your analysis skills for increased confidence in the quality of cellular and animal models.

Genome Engineering and Validation by Long Read Sequencing | Mary Lyon Centre

Get the best training in our state of the art training facility built to provide courses in genetics, pathology, transgenics and more!

000

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 21/07/2026

#Training: Our Laboratory Skills for Animal Technicians course is for #technicians who would like to develop their lab skills, including processing blood samples, dose calculations, and use of standard equipment. Join us in October:

000

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 16/07/2026

#Training: Book your place on our Mouse Necropsy practical training course to learn how to perform a basic standard mouse necropsy and describe gross observations made during this process This course is running again in November. Book now!

000

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 15/07/2026

Want to understand genetic drift and how to maintain integrity in both simple and complex genetically altered mouse lines? Book your place on our 3-day Mouse Genetics and Colony Management for Researchers course and join us in October!

Mouse Genetics and Colony Management for Researchers | Mary Lyon Centre

Get the best training in our state of the art training facility built to provide courses in genetics, pathology, transgenics and more!

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 14/07/2026

#Training: Basic lab skills are key to high quality, reproducible research. Our Practical Laboratory Skills course covers a range of basic skills, including use of standard equipment, such as centrifuges, balances, pipettes, and fume hoods We have multiple dates scheduled, including 16th September:

Practical Laboratory Skills | Mary Lyon Centre

Get the best training in our state of the art training facility built to provide courses in genetics, pathology, transgenics and more!

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 09/07/2026

#Training: Laboratory management is a subject that is often learned on the job, with limited training opportunities for those new to the role. This course is aimed at both researchers new to management and managers new to the lab setting.

Best Practices in Laboratory Management | Mary Lyon Centre

Get the best training in our state of the art training facility built to provide courses in genetics, pathology, transgenics and more!

000

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 09/07/2026

Today is Be Open about Animal Research Day #BOARD26. We are committed to openness and transparency about our use of animals, so today we are sharing our recently updated annual statistics for animal use at the MLC in 2025. www.har.mrc.ac.uk/news/use-of-...

A donut chart showing the numbers of procedures at different severity levels, with 77.1% of procedures sub-threshold, 18.5% mild, 3.6% moderate, 0.1% severe, and 0.7% non-recovery.

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 08/07/2026

We are #hiring a Mechanical Facilities Technician to join our Engineering and Estates Department, where they will undertake mechanical installation, maintenance, repairs & fault-finding on a variety of piped systems and building services, such as heating/cooling, HVAC, and steam Apply by 12th July

fa-evzn-saasfaukgovprod1.fa.ocs.oraclecloud.com

Mechanical Facilities Technician

Mary Lyon Centre at MRC Harwell | Open Ended | Salary: £33,419 - £37,582 | MRC Band 5 S1| Closing date: 12 July 2026

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 08/07/2026

We are excited to be announcing a new pump-prime funding scheme that has awarded funding to four collaborative projects that make use of the facilities and expertise of the Mary Lyon Centre, @rosfrankinst.bsky.social, and @diamondlightsource.bsky.social to address key questions in biology

Pump-prime funding strengthens collaboration across Harwell | Mary Lyon Centre

Get the best training in our state of the art training facility built to provide courses in genetics, pathology, transgenics and more!

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 08/07/2026

Don't forget to put together your application for our current Genome Editing Mice for Medicine call to be in with a chance of getting your free, novel, genetically altered mouse model generated by the Mary Lyon Centre. You have less than a week left to apply! Deadline: 13th July

GEMM | Mary Lyon Centre

Get the best training in our state of the art training facility built to provide courses in genetics, pathology, transgenics and more!

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 07/07/2026

#Training: Join us in October for our 2-day Mouse Necropsy and Tissue Processing course to learn how to perform a basic standard mouse necropsy, as well as how to treat collected tissues in preparation for histological processing and embedding: www.har.mrc.ac.uk/training/cou...

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 30/06/2026

We are #hiring a Mechanical Facilities Technician to join our Engineering and Estates Department, where they will undertake mechanical installation, maintenance, repairs & fault-finding on a variety of piped systems and building services, such as heating/cooling, HVAC, and steam Apply by 12th July

fa-evzn-saasfaukgovprod1.fa.ocs.oraclecloud.com

Mechanical Facilities Technician

Mary Lyon Centre at MRC Harwell | Open Ended | Salary: £33,419 - £37,582 | MRC Band 5 S1| Closing date: 12 July 2026

000

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 25/06/2026

#Training: Our Laboratory Skills for Animal Technicians course is for #technicians who would like to develop their lab skills, including processing blood samples, dose calculations, and use of standard equipment. Join us in October:

Laboratory Skills for Animal Technicians | Mary Lyon Centre

Get the best training in our state of the art training facility built to provide courses in genetics, pathology, transgenics and more!

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 23/06/2026

#Training: Our Practical Laboratory Skills course covers basic theoretical and practical lab skills, including use of standard equipment, such as biosafety cabinets, centrifuges, pipettes, and balances We have multiple dates through the year, including 15th July:

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 23/06/2026

#ICYMI MLC staff recently contributed to a paper with COST Action TEATIME colleagues on the importance of including both sexes in animal studies using home cage monitoring data to highlight sex-specific differences in behaviour and disease progression:

onlinelibrary.wiley.com

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Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 18/06/2026

#Training: Laboratory management is a subject that is often learned on the job, with limited training opportunities for those new to the role. This course is aimed at both researchers new to management and managers new to the lab setting.

000

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 18/06/2026

We are #hiring a Mechanical Facilities Technician to join our Engineering and Estates Department, where they will undertake mechanical installation, maintenance, repairs & fault-finding on a variety of piped systems and building services, such as heating/cooling, HVAC, and steam Apply by 12th July

fa-evzn-saasfaukgovprod1.fa.ocs.oraclecloud.com

Mechanical Facilities Technician

Mary Lyon Centre at MRC Harwell | Open Ended | Salary: £33,419 - £37,582 | MRC Band 5 S1| Closing date: 12 July 2026

000

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 17/06/2026

#Training: Book your place on our Mouse Necropsy practical training course to learn how to perform a basic standard mouse necropsy and describe gross observations made during this process This course is running again in November. Book now!

Mouse Necropsy | Mary Lyon Centre

Get the best training in our state of the art training facility built to provide courses in genetics, pathology, transgenics and more!

000

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 16/06/2026

Want to understand genetic drift and how to maintain integrity in both simple and complex genetically altered mouse lines? Book your place on our 3-day Mouse Genetics and Colony Management for Researchers course and join us in October!

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 11/06/2026

Many congratulations to Lizzy Fisher, a former PhD student and later Programme Leader at MRC Harwell, who was recently elected a Fellow of the Royal Society

Elizabeth Fisher elected a Fellow of the Royal Society | Mary Lyon Centre

"The people I’ve worked with at Harwell have had a huge part in shaping my career, so this is for you too.”

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 11/06/2026

#Training: Join us in October for our 2-day Mouse Necropsy and Tissue Processing course to learn how to perform a basic standard mouse necropsy, as well as how to treat collected tissues in preparation for histological processing and embedding:

Mouse Necropsy and Tissue Processing | Mary Lyon Centre

Get the best training in our state of the art training facility built to provide courses in genetics, pathology, transgenics and more!

000

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 11/06/2026

Don't forget to put together your application for our current Genome Editing Mice for Medicine call to be in with a chance of getting your free, novel, genetically altered mouse model generated by the Mary Lyon Centre. 🔬 Find out more and apply:

GEMM | Mary Lyon Centre

Get the best training in our state of the art training facility built to provide courses in genetics, pathology, transgenics and more!

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 09/06/2026

#Training: Our new 2-day Using Conditional Transgenic Models course is designed for anyone using or planning to use conditional models and will equip trainees with a clear understanding of how these models function biologically, as well as the practical ways in which they can fail. Join us in June:

Using Conditional Transgenic Models | Mary Lyon Centre

Get the best training in our state of the art training facility built to provide courses in genetics, pathology, transgenics and more!

000

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 02/06/2026

#Training: Cryopreservation allows long-term storage of embryos and sperm, providing a convenient way to preserve, protect, and transport your mouse line, as well as removing the need for continued animal breeding. Book your place on our Cryopreservation course now!

Mouse Embryo and Spermatozoa Cryopreservation Course | Mary Lyon Centre

Get the best training in our state of the art training facility built to provide courses in genetics, pathology, transgenics and more!

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 28/05/2026

#Training: Laboratory management is a subject that is often learned on the job, with limited training opportunities for those new to the role. This course is aimed at both researchers new to management and managers new to the lab setting.

Best Practices in Laboratory Management | Mary Lyon Centre

Get the best training in our state of the art training facility built to provide courses in genetics, pathology, transgenics and more!

Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 28/05/2026

The MRC Centre for Macaques is #hiring an animal #technician to look after the health and welfare of a breeding colony of rhesus macaques Apply by 1st June

fa-evzn-saasfaukgovprod1.fa.ocs.oraclecloud.com

Animal Technician

Centre for Macaques, MRC Harwell | Fixed term until 31 March 2028 | Salary: £27,406-£27,937 per annum, dependent on skills and experience | Band MRC-6a S2 | Closing date: 01 June 2026