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Johannes Morstein

@morstein.bsky.social

1.6K followers 810 following 24 posts

Assistant Professor at Caltech | Chemical Biologist morsteinlab.caltech.edu

Johannes Morstein @morstein.bsky.social · 27/04/2026

Finally, we introduced bifunctional lipid probes that enable selective labeling and visualization of distinct lipid classes in living cells

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Johannes Morstein @morstein.bsky.social · 27/04/2026

We extended this approach to alkylglycerols and sphingosines to selectively access subsets of ether lipids and sphingolipids

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Johannes Morstein @morstein.bsky.social · 27/04/2026

Systematic chemical modifications enabled new and more selective metabolic incorporation, allowing to target subsets of glycero(phospho)lipids.

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Johannes Morstein @morstein.bsky.social · 27/04/2026

We started out by mapping the structural dependence of lipid metabolism using isotope tracing, showing that lipid tail structure directs metabolic fate across the lipidome (Figure 1)

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