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Reposted by Clint Valentine

Fulcrum Genomics @fulcrumgenomics.com · 03/12/2025

Proud to share that our own Clint Valentine co-authored MutSeqR, an open-source R package for analyzing error-corrected sequencing (ECS) data. Developed with Health Canada & U Ottawa, it helps bring consistency to genetic safety research. 🔗 doi.org/10.1093/bioa... #Genomics #OpenSource #MutSeqR 🧬🖥️

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Clint Valentine @moonlight.bio · 07/11/2025

I do this! I encode first, and provide a "was UTF-8 encoded" marker in the INFO header so I auto-detect when I've done it and decode when reading. Helpers here: github.com/clintval/tp5... ^ not actually encoding JSON in that tool, but other kinds of structured text with chars that are illegal.

github.com

tp53/scala/seshat/src/io/cvbio/seshat/VcfUtil.scala at 400b3e35f83175dfe59891cbc6906f2cfb7738c4 · clintval/tp53

Tools for programmatically annotating VCFs with the Seshat TP53 database - clintval/tp53

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Clint Valentine @moonlight.bio · 23/07/2025

Treat AI agents like junior developers, coaching them through the bigger picture. As reliance on AI agents increases, will we see a hollowing-out of junior devs opportunity for receiving coaching and training? How will new developers cross this chasm in the future without opportunity?

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Clint Valentine @moonlight.bio · 16/04/2025

Python is a simple language, but using it isn't always easy. Today I reflected on the following code. To really understand it, one must learn: generators, type hinting, pytest fixtures, advanced usage of fixtures, monkey patching the OS environment, mocking impure environments, generators...

A Python programming snippet that uses pytest, pytest fixtures, advanced use of fixtures, monkey patching the OS environment, type hinting, mocking impure environments, and generators.

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Clint Valentine @moonlight.bio · 30/10/2024

This is pretty cool. Thanks for sharing! Yes it indeed looks like me :)

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Reposted by Clint Valentine

Rob Patro @robp.bsky.social · 08/09/2023

Noticing a lot more genomics and bioinformatics peeps on here recently; welcome! I'm still not seeing a ton of genomics/bioinfo "content", so if there's a curated feed you use please share :).

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