Reposted by Richard BaylissEMBO Reports @emboreports.org · 28/01/2026Jennifer A Miles, molecularrichard.bsky.social et al model the Aurora A-Bora-Plk1 ternary complex revealing how Bora bridges both kinases #RefereedPreprint @reviewcommons.org link.springer.com/article/10.1... 042
Reposted by Richard BaylissStephen Royle @steveroyle.bsky.social · 23/04/2025I wrote something about why giving negative feedback to your colleagues can be a bit like slaying vampires in The Lost Boys, or something like that. quantixed.org/2025/04/23/f...quantixed.orgFeedback Deficiency: the tricky art of effective peer feedback – quantixed 031
Richard Bayliss @molecularrichard.bsky.social · 21/03/2025A masterclass in molecular imaging - too exciting for (this former NPC-phile's) words! 000
Richard Bayliss @molecularrichard.bsky.social · 21/03/2025First post on here to mark the lab's first paper of the year. It's a belter. The product of several collaborations, many techniques skilfully applied and incredible persistence. 1/n doi.org/10.1083/jcb....doi.orgStructural characterization and inhibition of the interaction between ch-TOG and TACC3 | Journal of Cell Biology | Rockefeller University PressShelford, Burgess, and colleagues present a structural model of the interaction between TACC3 and ch-TOG. They discover Affimers that can inhibit this inte 1126
Reposted by Richard BaylissStephen Royle @steveroyle.bsky.social · 20/03/2025AlphaFold was a game changer for this project. AF stories are a bit boring aren't they? It helped really us to make sense of our structural data. With some neat HDX-MS experiments, it all came together. A big thank you to all the authors, it's great to see it published! 3/n doi.org/10.1083/jcb....doi.orgStructural characterization and inhibition of the interaction between ch-TOG and TACC3 | Journal of Cell Biology | Rockefeller University PressShelford, Burgess, and colleagues present a structural model of the interaction between TACC3 and ch-TOG. They discover Affimers that can inhibit this inte 021
