Developing Novel Methodologies to Improve Healthcare Wearable Sensor + Multiome + ML/DL + Statistics

Our research focuses on the molecules that mediate the beneficial effects of physical activity and exercise to human health.

The Rosenzweig laboratory is interested in why the heart fails. Heart failure is an enormous and growing cause of death and disability throughout the world. In addition, the heart provides a model…

This Review defines seven hallmarks of skeletal muscle homeostasis, providing a unifying framework for understanding, measuring and preserving muscle health.

News from Frankel IHBH

Hanyu Qian 1 2 3, Chao Wu 1 3, Bo Li 1, Anthony Rosenzweig 1, Meng Wang 1 2 4

Enhancing the Michigan Medicine Research Community

The Stanley and Judith Frankel Institute for Heart and Brain Health (Frankel IHBH) and the Biointerfaces Institute (BI) have launched the Brain-Body Crosstalk in Health and Disease Challenge.

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Summer 2026 | V.8

Health Lab talks to Jorge Ruas, Ph.D., of the U-M Department of Pharmacology, about peptides, how they work and whether supplementing them lends any benefit.

Spring Issue | V.7

The Stanley and Judith Frankel Institute for Heart and Brain Health (Frankel IHBH), Caswell Diabetes Institute (CDI), and the Michigan Diabetes Research Center (MDRC), are delighted to announce the…

The Stanley and Judith Frankel Institute for Heart and Brain Health (Frankel IHBH) is proud to announce Aurel B. Leuchtmann, Ph.D., as the inaugural Frankel IHBH Postdoctoral Fellow.

The Stanley and Judith Frankel Institute for Heart and Brain Health (Frankel IHBH) is proud to announce Aurel B. Leuchtmann, Ph.D., as the inaugural Frankel IHBH Postdoctoral Fellow.

Search and explore proteomics association and MR causal relationship analysis results

Mapping Molecular Links Between Heart and Brain Disease

Search and explore proteomics association and MR causal relationship analysis results

Mapping Molecular Links Between Heart and Brain Disease

CS014 represents a novel HDAC inhibitor with the potential for reducing hepatotoxicity while maintaining the benefit of preventing injury-induced clotting without increased bleeding diathesis.

CS014 represents a novel HDAC inhibitor with the potential for reducing hepatotoxicity while maintaining the benefit of preventing injury-induced clotting without increased bleeding diathesis.

#OurHearts is an inspiring way for The Heart Truth® to encourage and motivate everyone to adopt heart-healthy behaviors, together. Research shows having social

Khetarpal et al. show that the metabolic regulator PGC-1α is essential in heart muscle cells for exercise-driven cardiac growth, and that suppression of the stress-induced myokine GDF15 is required to enable cardiomyocyte adaptations to training.