Incredibly proud to see our latest work out in Nature Genetics: www.nature.com/articles/s41...
Here we share our FLAMES framework, which predicts the effector genes in GWAS loci with state-of-the-art precision🔥
Special thanks to @daniposthu.bsky.social
A full thread describing findings below!
rdcu.be
Prioritizing effector genes at trait-associated loci using multimodal evidence
Nature Genetics - FLAMES is a machine learning approach combining variant fine-mapping, SNP-to-gene annotations and convergence-based gene prioritization scores to identify candidate effector genes...