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Matthew J Randell @mjrandell.bsky.social · 11/08/2025

New paper sharing mothers' experiences of Down syndrome screening, including how the way their screening test result was communicated impacted them. It calls for a more neutral approach to this chance communication, and for welcoming a diversity of choices. onlinelibrary.wiley.com/doi/10.1002/...

onlinelibrary.wiley.com

Down Syndrome in Maternity Care: Mothers' Experiences of Prenatal Screening

Prenatal screening for Down syndrome (DS) is offered to expectant parents receiving antenatal care in many countries, with an emphasis on providing parents with the opportunity to make informed choic...

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Matthew J Randell @mjrandell.bsky.social · 11/08/2025

I forget to promote papers when they come out. Mortality data takes a long time to collect! Read this collaborative systematic review and meta analysis on the potential use of surrogate outcomes (such as late-stage cancer incidence!) in cancer screening trials. pubmed.ncbi.nlm.nih.gov/40694037/

pubmed.ncbi.nlm.nih.gov

LATE-STAGE OUTCOMES AS SURROGATES FOR MORTALITY IN CANCER SCREENING TRIALS: A SYSTEMATIC REVIEW AND META-ANALYSIS - PubMed

Late-stage cancer incidence has been proposed as a surrogate outcome for cancer-specific mortality in future screening trials. Two previous meta-analyses with 33 and 39 trials assessed trial-level sur...

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Matthew J Randell @mjrandell.bsky.social · 09/05/2025

PGBC 2025 has landed! 4th-5th September at the Ethox centre, University of Oxford. We welcome abstracts from postgraduates in any discipline broadly on the theme 'Disruption in Bioethics'. Abstract deadline extended to 21st May, submit here: ime.datawareonline.co.uk/Event-Bookin...

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