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Michael Payne

@mjohnpayne.bsky.social
157 followers 343 following 2 posts

Senior Research Fellow at University of Sydney. Microbial genomics, Bioinformatics and Python!

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Michael Payne @mjohnpayne.bsky.social · 26/05/2026
Finally a preprint for our tool DAMPA (Australiana included) that generates efficient probe panels for targeted metagenomics from pangenome graphs. Presented at ABPHM and ABACBS last year. www.medrxiv.org/content/10.6...
medrxiv.org
DAMPA - accelerated and simplified design of probe panels for targeted metagenomics using pangenome graphs
Targeted metagenomics, where samples are enriched for multiple organisms of interest using oligonucleotide probes, is a highly efficient sequencing methodology that is becoming standard practice for g...
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Reposted by Michael Payne
David Ma @frostickle.bsky.social · 25/11/2025
Great talk from Michael Payne at #ABACBS2025 on DAMPA - tool for designing probe panels for targeted metagenomics using pangenome graphs! Captures all diversity efficiently, uses fewer probes than competitors. Critical for syndromic surveillance! 🧬🔬 #Metagenomics
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Michael Payne @mjohnpayne.bsky.social · 26/05/2025
Had a great time at #ABPHM where I presented our new tool github.com/Multipathoge.... DAMPA uses pangenome graphs to design targeted metagenomics probe panels that minimise probe number while retaining very high target coverage. Preprint coming soon!
github.com
GitHub - MultipathogenGenomics/dampa: Dampa: Diversity Aware Metagenomic Panel Assignment
Dampa: Diversity Aware Metagenomic Panel Assignment - MultipathogenGenomics/dampa
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