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Maiato Lab

@mitosisrocks.bsky.social
95 followers 110 following 5 posts

News from the Maiato lab @i3S (Porto), studying chromosome instability and dynamics. Posts by lab members.

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Maiato Lab @mitosisrocks.bsky.social · 09/09/2026
A long time in the making, now finally out.💥 Our new study shows that division stays on time when kinetochore–microtubule attachments form efficiently. When the process drags, that delay is remembered, limiting future cell proliferation. www.nature.com/articles/s41... #mitosis #biology #microscopy
nature.com
Low kinetochore-microtubule occupancy leaves a mitotic memory by delaying checkpoint silencing - Nature Communications
How do cells faithfully segregate chromosomes within an optimal time? Using naturally “super-resolved” kinetochores, the authors show that maximal microtubule occupancy prevents bad mitotic memories t...
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Maiato Lab @mitosisrocks.bsky.social · 03/09/2026
What is the sequence of events at the kinetochore? Our Spotlight article highlighting a beautiful study by Conway et al. is out now in Trends in Cell Biology! Click here for download: sl1nk.com/euzlpiq A temporal framework for error-free mitosis: Trends in Cell Biology www.cell.com/trends/cell-...
cell.com
A temporal framework for error-free mitosis
The spindle assembly checkpoint (SAC) promotes mitotic fidelity by delaying anaphase until all kinetochores are stably attached to spindle microtubules. SAC silencing is increasingly recognised as a d...
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Reposted by Maiato Lab
Carlos Conde @carlos-conde.bsky.social · 18/08/2026
Our latest preprint: elevated MPS1 drives CIN in colon cancer by sustaining the fibrous corona at metaphase kinetochores. This untimely persistence creates an extra microtubule-engagement domain providing a structural basis for merotely and chromosome mis-segregation. doi.org/10.64898/202...
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Maiato Lab @mitosisrocks.bsky.social · 11/08/2026
Learn more about the clinical relevance of the tubulin code in our comprehensive review, recently published in Cancer and Metastasis Reviews. #Cancer #Tubulin link.springer.com/article/10.1...
link.springer.com
Prognostic, diagnostic and therapeutic value of the cancer tubulin code - Cancer and Metastasis Reviews
Microtubules are essential cytoskeleton polymers composed of α/β-tubulin heterodimers that play a central role in the regulation of various cellular processes, including cell division, cell shape, cel...
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Reposted by Maiato Lab
Eurico Morais-de-Sá @polarityi3s.bsky.social · 15/04/2026
Drosophila border cells are beautiful to watch… but far from easy to image. Kudos to the brave and skilled @vitoryang.bsky.social, who took on the challenge of establishing border cell migration imaging in the lab! His movies are astonishing, and now our first-ever study on #cell #migration is out!
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Maiato Lab @mitosisrocks.bsky.social · 15/04/2026
Saying our farewells at the amazing #SpindleCroatia2026 meeting after four days of inspiring science! See you in 2029! 🦌
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Reposted by Maiato Lab
Iva Tolić @ivatolic.bsky.social · 14/04/2026
Spindle squad #SpindleCroatia2026 #Dubrovnik www.phy.pmf.unizg.hr/~mitosis/
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Reposted by Maiato Lab
Monica Bettencourt-Dias @monicabettencourt.bsky.social · 09/02/2026
Last days to apply this position in our group! Do join us in this great Institute @crg.eu, with great colleagues, and help shaping the science and culture of our lab!
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Maiato Lab @mitosisrocks.bsky.social · 29/01/2026
Mitosis has a timing system. If chromosomes attach properly, cells divide on schedule and keep proliferating. If attachment is slow or incomplete, the delay is recorded — and daughter cells stop dividing. We explore this link in our new preprint. 🔗 www.biorxiv.org/content/10.6...
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