At first, Aubrey Hasley thought she was having a migraine. As the room spun and she struggled to walk, she realized something worse was occurring.

The Charlotte Woodward Organ Transplant Discrimination Act would end the practice of denying transplants to people with Down syndrome.

Jessica Wozniak thought that some of the symptoms of norovirus were lingering. They were signs of Stage 4 colon cancer.

Two weeks after finishing a marathon, John Johnson was diagnosed with Stage 2 colorectal cancer. He shares his story to raise awareness and offer hope.

At 16, Eldiara Doucette felt arm pain. It was 1st sign of rare soft tissue cancer that led to amputation.

Journi Kelly, 11, needed a new heart. But her heart valves helped 2 other girls and allowed doctors to perform the 1st living mitral valve replacement.

“Flu is more than just a cold. It is serious,” Kaitlyn Covert says.

In his first interview since his wife's death, Caden Hutchins tells TODAY.com about her early symptoms and positive attitude over the past two years.

Lainie Jones has Li-Fraumeni syndrome, which makes her predisposed to having cancer. She's undergoing treatment for glioblastoma, her 7th cancer.

In fall 2023, Earlie Smith experienced an aortic dissection. Months later, her brother, Larry Smith, also had one. The same doctor helped them both.

Sidney Barbier learned she had Nutcracker syndrome and underwent surgery. Now the college cross-country skier is able to compete without pain.

Yovana Portillo felt stunned that she had lung cancer because she never smoked. But she hopes people realize that lung cancer can happen to anyone.

Emily Campbell visited several doctors before undergoing an ultrasound that led to a diagnosis. Now, she's encouraging others to advocate for themselves.

Clayton Moorse's parents couldn't slip a T-shirt over his torso because of his distended stomach. Tests revealed the toddler had a Wilms tumor.

Katie and Lyndsay Cooper have the BRCA1 mutation and started screening early. They both discovered lumps in their breast, leading to their diagnoses.

Grayson Niemi learned he had Stage 2 testicular cancer shortly after his freshman year of college.

When Chris Kirmsse told daughter Christine Kirmsse that her blood pressure was 200/100, Christine Kirmsse made her get medical care.

While facing a rare cancer diagnosis was tough, Nick Pastuovic transformed his mindset about life, becoming a more positive person during treatment.

Molly Young's twin daughters had the flu so when she experienced a headache, nausea, she assumed she had it, too. She felt surprised she had a brain tumor.

Casandra Costley thought bleeding and rectal pain were normal. She wishes she would shared her symptoms with her doctor sooner to avoid a Stage 4 diagnosis.

When Gracelyn Stiffler struggled with headaches and started walking strangely, her mom knew something was seriously wrong, even though doctors dismissed her.

Doctors first diagnosed Lance Bass with Type 2 diabetes, but lifestyle changes and medication didn't work.

At only 9, Prince Wise has refined food tastes. When Make-A-Wish needed a past recipient to make a signature meal as a fundraiser, the organization turned to Prince.

The star shares the first symptom that led to his Stage 3 cancer diagnosis, how he's coping and why he wants others to be vigilant about their health.

Jessie Malone considered taking a nap but her Apple Watch kept 'blaring' a warning that she needed medical attention.

Tracy Dixon-Salazar hoped studying science would help her understand research about her daughter's condition. She had no idea she'd find a treatment option.

Jamie Ball thought she had gallstones when her side hurt. After she was diagnosed with stage 4 colon cancer, she learned she'd need a new liver to live.

Going through premature menopause, which starts before 40, can feel isolating and lead to health problems later.

Johanna Mendoza developed red splotches on her wrist and belly and attributed it to something she ate. She felt stunned to learn she had leukemia.

"We’re still participating in this research even though our son passed away, and that still adds meaning to his life."

When Hillary Steffen experienced tingling, numbness and vomiting she went to the hospital. She felt stunned to learn she had acute heart failure.

The first-year teacher thought the intense abdominal pain was from under cooked salmon. He felt stunned to learn it was a sign of colon cancer.

Two women share their experiences with the cancer so that others do not go through what they experienced.

When Amanda Banic experienced chest pain a second time, her husband insisted she return to the hospital. She had an aortic dissection that could have killed her.

Over the years, Chloe Melas grappled with ulcerative colitis ruining big moments. Thanks to better medical management and lifestyle changes, she finally has fewer symptoms.

Angela Ellis had what she thought was a benign mass removed. When she received her pathology report, she realized she had triple negative breast cancer.

Ido Simyoni has fibrous dysplasia and benign tumors grow into his skull. A doctor performed 2 surgeries to reduce infection and reconstruct his forehead.

After Jill Zinsmeyer Googled elevated tryptase levels, she learned of systemic mastocytosis. It took years for doctors to diagnose her with it.