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mikeehrenstein.bsky.social

@mikeehrenstein.bsky.social
36 followers 14 following 6 posts

Professor of Rheumatology at UCL

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mikeehrenstein.bsky.social @mikeehrenstein.bsky.social · 03/12/2025
Visit poster 86 today to find out about IgA and lupus at the #bsi2025 and talk to @clairebeesley.bsky.social
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mikeehrenstein.bsky.social @mikeehrenstein.bsky.social · 17/10/2025
Just out! We challenge the prevailing caution and advocate for a biomarker-guided approach soon to be tested in the STRATIFY lupus trial: Rituximab–belimumab combination for refractory SLE @shipam.bsky.social @versusarthritis.bsky.social www.thelancet.com/journals/lan...
thelancet.com
Revisiting safety and refining benefit of rituximab–belimumab combination for refractory SLE
B-cell depletion using rituximab is used to treat systemic lupus erythematosus (SLE), particularly for patients whose disease is refractory to conventional immunosuppressants (eg, mycophenolate), and ...
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Reposted by @mikeehrenstein.bsky.social
shipam.bsky.social @shipam.bsky.social · 23/07/2025
@arrdept-ucldom.bsky.social Just out! Our latest lupus paper shows IgA2⁺ B-cells & IgA2-anti-dsDNA Abs are selectively targeted doi.org/10.1016/j.xc... Builds on theranostic discovery doi.org/10.1016/S266... On BEAT-Lupus doi.org/10.7326/M21-... Lupus ≠ one-size-fits-all doi.org/10.1084/jem....
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Reposted by @mikeehrenstein.bsky.social
UCL Dept of Aging, Rheumatology & Regenerative Medicine @arrdept-ucldom.bsky.social · 23/07/2025
So fantastic to see this work out @shipam.bsky.social, with Prof Michael Ehrenstein and Dr Dan McCluskey. This new departmental paper shows the utility of anti-dsDNA IgA2 and IgA2+ B cells as a biomarker for response to Belimumab in SLE. Read in @cp-cell.bsky.social journal - Cell Reports Medicine.
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mikeehrenstein.bsky.social @mikeehrenstein.bsky.social · 12/05/2025
www.nihr.ac.uk/story/strati... a big thank you to the lupus specialists and their patients who made this research possible
nihr.ac.uk
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mikeehrenstein.bsky.social @mikeehrenstein.bsky.social · 09/05/2025
www.independent.co.uk/news/health/...
independent.co.uk
Simple blood test offers new hope to lupus patients
Up to 69,000 people in the UK have lupus, a chronic autoimmune condition
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mikeehrenstein.bsky.social @mikeehrenstein.bsky.social · 28/03/2025
STRATIFY lupus is a newly funded precision medicine biomarker enrichment trial funded by @versusarthritis.bsky.social and @nihr.bsky.social with support from @glaxosmithkline.bsky.social in collaboration with @shipam.bsky.social & many UK lupus specialist centres. Will start recruitment early 2026.
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