Sign in

Susan Cox

@micoxscopy.bsky.social
69 followers 28 following 7 posts

Microscopy. Computer vision. Cell cytoskeleton. King's College London

PostsRepliesMedia
Reposted by Susan Cox
Julia Sero @cellmorphosero.bsky.social · 04/12/2025
I can highly recommend! Excellent value. :)
123
Susan Cox @micoxscopy.bsky.social · 20/08/2025
Our published version only deals with single colour data, but we are developing multi-colour analysis. Tests so far indicate an advantage to using one colour to obtain the pose and then limiting to finer alignments. Would be very happy to discuss your data! Always looking for new test cases.
110
Susan Cox @micoxscopy.bsky.social · 19/08/2025
Some fowl play here: vision language models are biased against 3-legged chickens, say they have 2 or 4 legs vlmsarebiased.github.io
A picture of a three legged chicken with the number of legs returned by different vision language models (2 or 4)
131
Susan Cox @micoxscopy.bsky.social · 12/08/2025
Many thanks to my fantastic collaborators including @deathandthepenguin.bsky.social, @mmlab.bsky.social‬, @christlet.bsky.social‬, @georgelittlejohn.bsky.social‬, @katherine-baxter.bsky.social, @gailmcconnell.bsky.social‬, @superresolusian.bsky.social (5/5)
030
Susan Cox @micoxscopy.bsky.social · 12/08/2025
If you’d like to try SQUASSH our code is on github and includes a colab notebook. github.com/edrosten/SQU... colab.research.google.com/github/edros... If your analysis requires a custom heterogeneity and you’d like some help, get in touch! (4/5)
github.com
GitHub - edrosten/SQUASSH
Contribute to edrosten/SQUASSH development by creating an account on GitHub.
231
Susan Cox @micoxscopy.bsky.social · 12/08/2025
…and visualise structures and heterogeneity from the 8 nm alpha-tubulin repeat up to the mm scale.(3/5)
Top row shows spectrin rings in axons, middle row shows cell division, and bottom row shows plant trichomes.
130
Susan Cox @micoxscopy.bsky.social · 12/08/2025
By creating a structural model taking all the data into account and fitting the position, rotation, and heterogeneity in each observation of a structure, we can spot systematic biases in localisation microscopy data… (2/5)
Top row of image show nuclear pore structures derived from RESI data on the left and from 4Pi STORM and the right. Bottom graph shows that the RESI results show a correlation between the two rings of the nuclear pore structure and the z position, while the 4pi results show no such correlation
130
Susan Cox @micoxscopy.bsky.social · 12/08/2025
How do you quantify cell structures which are deformed between different observations? Our preprint shows how to perform Simultaneous QUAntification of Structure and Structural Heterogeneity (SQUASSH) on 3D fluorescence microscopy data. (1/5) www.biorxiv.org/content/10.1...
biorxiv.org
Extracting biological structure and heterogeneity from the nano to the macro scale
Fluorescence microscopy is an essential tool in biology. It has revealed great variability at multiple scales, in macromolecular complexes, cells, and organisms. Understanding this variability will re...
1276