Reposted by Michael Jain
'Why we have evolved so many cytokines for so few transcriptional regulators is not entirely known, but it suggests that the diversity in cell types that can send a signal and cell types that can receive them is more important than diversity in transcriptional programs.'
cell.com
Cytokines in cancer
Kureshi and Dougan discuss the roles of cytokines in the tumor microenvironment. Although
there is a sophisticated understanding of cytokine networks, therapeutically targeting
cytokine pathways in ca...