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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 08/10/2026

Welcome to the comeback of our #ThrowbackThursday series! 🚀 Every week, we’ll revisit impactful research from MHR. To kick things off: Why does oocyte quality decline with age? 🤔 We look back at a standout article exploring the molecular mechanisms. 🧵 1/2

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 07/10/2026

🌟 Meet MHR Associate Editor Dr. Alexandra Harvey! ✅ Why Publish with MHR? MHR is a high impact journal that prioritises quality and rigor in its peer-review system, with a commitment to publishing science that will improve clinical outcomes. 🔗 Board: academic.oup.com/molehr/pages...

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 05/10/2026

Hormones aren't everything in endometriosis: lipid metabolism is key too! 🤔🩸🔬 A new paper published in MHR study reveals sphingomyelin is a metabolic hub, and its hydrolysis causes severe ceramide accumulation in lesions. 📉🧬

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 25/09/2026

🔬 MHR is proud to sponsor the Bedford Research Foundation's workshop: "Unique Human Egg Activation Pathways." 🗓️ Nov 6, 2026 📍 Dedham, MA & Online ⏳ Early Bird ends Oct 1! Limited spaces available. Secure your spot: lnkd.in/eFgWkxkA#Rep... #StemCells

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 23/09/2026

🌟 Meet MHR Associate Editor Joshua Johnson (CU Anschutz)! 🔬 He researches ovarian function to improve assisted reproductive tech. 🔗 Board: bit.ly/MHR_Board 🔗 Submit: bit.ly/MHR_Submissions #ReproductiveBiology

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 21/09/2026

🧬 When do de novo mutations truly arise? While germ cells are the traditional suspects, new research shifts focus to the moments just after fertilization. Check out our latest paper: "Maternal DNA repair safeguards genome stability during the oocyte-to-embryo transition."🧵👇

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 18/09/2026

How exactly does an embryo penetrate the endometrial epithelium during implantation? 🤔 A new MHR study by L. Izmaylova & colleagues (Leube Lab) explores this using a 3D in vitro model, tracking fluorescent trophoblast spheroids in real time! 🔬 🧵 1/2

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 16/09/2026

🌟 Meet MHR Associate Editor Pablo E. Visconti (@UMassAmherst)! 🔬 Research: Sperm capacitation, fertilization & embryo development. 💡 Why MHR? "Fast reviews & no charges to submit or publish!"👇 👥 Board: bit.ly/MHR_Board 📝 Submit: bit.ly/MHR_Submissions

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 14/09/2026

🔍 How do sperm acquire motility and the potential to fertilize? The secret lies in epididymosomes. Excited to highlight a new review in Molecular Human Reproduction by Wei et al. exploring how these nanoscale vesicles drive vital communication in the reproductive tract. 🧵 1/2

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 09/09/2026

🌟 Meet MHR Associate Editor Rocío Martínez Aguilar! At @EdinburghUni, she researches heavy menstrual bleeding mechanisms to find non-hormonal treatments. 🩸🔬 Boost your early-career portfolio & publish with MHR! 👇 👥 Board: bit.ly/MHR_Board 📝 Submit: bit.ly/MHR_Submissions

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 07/09/2026

👋 Goodbye summer holidays, hello the future of male contraception! 🔬 Ease back into routine with our latest Editor's Choice by Aditi Khamamkar et al. from Dr. Souvik Dey's lab (MAHE) & Broad Institute. 🔓 Read this Open Access study here: lnkd.in/eUvT2pia 🧵 1/2

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 03/09/2026

Meet MHR Associate Editor Xiaofei Sun! 👋 👨‍🔬 Research Assoc. Prof @cincychildrens.bsky.social. 🔬 Focus: uterine receptivity & placental development. 💡 "MHR's strong reputation makes it an ideal platform." 🤝 Board: bit.ly/MHR_Board 📝 Submit: bit.ly/MHR_Submissi...

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 05/08/2026

It's Wednesday! 🌟 Time to meet the people driving MHR forward. Spotlight on Valentina Lodde, Commissioning Associate Editor & Assoc. Prof at Univ. of Milan! 👋👩‍🏫 Check out why she values our peer-review process below 👇 🤝 Board: bit.ly/MHR_Board 📝 Submit: bit.ly/MHR_Submissions #MHR

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 03/08/2026

Back to the lab? 🌴➡️🔬 It’s officially August! As many return from a July break with recharged batteries, it’s the perfect time to set new goals. And we have a major one for you... How about joining us in Stockholm? 🇸🇪✈️👇

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 31/07/2026

🔬 How do microRNAs coordinate human placental development? A new study in @MHR_Journal maps miRNA–gene co-regulation across pregnancy: 🔹 1st tri: Maternal circulating EVs lead 🔹 3rd tri: Placental tissue leads 🔹 Linked to TGF-β & birth weight 📖 academic.oup.com/molehr/advan...

academic.oup.com

The miRNA-coordinated synergism for placental gene regulation throughout pregnancy

Abstract. The regulation of gene expression by microRNAs (miRNAs) is essential during development. However, it is necessary to move beyond individual miRNA

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 29/07/2026

🌟 Meet MHR Associate Editor Cameron Schmidt! 👋 👨‍🏫 Asst. Prof at East Carolina Univ studying spermatogenesis. 💡 Why publish with MHR? "Rigorous standards, efficient & transparent review." 🤝 Board: lnkd.in/ePqiktxA 📝 Submit: lnkd.in/eGXVN8da #MHR

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 24/07/2026

How often do we hear that androgen signaling is required for testis formation? Spoiler alert: It isn't! 🛑 A common misconception in reproductive science is equating androgen-dependent masculinization with testis development itself. 🧵 1/4

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 22/07/2026

🌟 Meet MHR Associate Editor, Sandra Laurentino (Univ. of Münster)! 🔬 She researches epigenetics & gene regulation in the human testis. Publish with us for a rigorous & fair peer review! 💡 🤝 Board: academic.oup.com/molehr/pages... 📝 Submit: academic.oup.com/molehr/pages... #Epigenetics

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ESHRE @eshre.bsky.social · 22/07/2026

🔬 Join #ESHRE’s Campus course and explore ICSI gamete selection, micromanipulation techniques, embryo & blastocyst biopsy, and lab troubleshooting through lectures, discussions and hands-on sessions. 📍 Lisbon, Portugal | 1–3 Oct 26 www.eshre.eu/Education/Calendar-Cam…

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 20/07/2026

🌟 MHR Editor's Choice 🌟 We're highlighting a key review on endometrial epithelium by Subramaniam, Gargett, Fitzgerald, Montgomery & McKinnon. Explore the unique biology behind cyclical regeneration and unexpected somatic mutation rates. 🧵👇 📖 academic.oup.com/molehr/artic...

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 17/07/2026

📢 We are thrilled to introduce a new article type to MHR: Concise Communications! 📝✨ Have a firm conclusion that doesn't need a full manuscript? Or a provocative finding to share while completing long-term research? This short-format, peer-reviewed option is for you. 🧵👇

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 14/07/2026

🚨 New in MHR: A promising step forward in non-hormonal contraception! Justine Fischoeder, Carla Ritagliati, and team just published a new Concise Communication on assessing the efficacy of ADCY10 inhibitors in cervical mucus. 🧬 🔗 Read here: academic.oup.com/molehr/artic... 🧵👇

academic.oup.com

Assessing efficacy of ADCY10 inhibitors in cervical mucus

Abstract. Male fertility depends on sperm motility, which enables sperm to traverse the female reproductive tract to the site of fertilization. Soluble ade

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Oxford Academic @academic.oup.com · 06/07/2026

Feeling Innovative? ESHRE are inviting early career scientists to submit their work for the chance to win #Molehr's coveted ECI Series Award. Find out more: oxford.ly/4kMVjqw @mhr-reprodsci.bsky.social #ESHRE2026 | #Reprosky

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MHR Early Career Innovator Series

MHR is pleased to announce that, throughout 2024 and 2025, our Early Career Innovator Series has gone from strength to strength. As a result, this initiative wi

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 03/07/2026

🔬 Breakthrough in male infertility publishet in MHR: Researchers at Weill Cornell have created functional male gametes entirely from stem cells, bypassing the need for an animal host! They engineered a 3D calcium alginate niche to support in vitro spermatogenesis. 🧵 🔗 lnkd.in/eQntr2ME

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 01/07/2026

Happy Wednesday! 🌟 Meet MHR Associate Editor, Prof. Dr. Daniela Fietz (University of Giessen)! 👋 🔬 She researches the intersection of immunology & reproduction, focusing on testis biology & spermatogenesis. Get to know the board: lnkd.in/eaMkq7yH #MHR #ReproductiveBiology

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 29/06/2026

Thrilled to see @Nature highlight an MHR paper by Dr. Francesca Duncan & team! 🔬 They challenge the traditional view of the ovary as solely a reproductive organ, uncovering an unexpected immune role. A paradigm shift for #WomensHealth! Read here: lnkd.in/ehuJXuvz

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Edited embryos tell secrets of development

For the second time this month, researchers have used base editing — a precise gene-editing technique — to alter the DNA of human embryos. The team found that a key protein called NANOG plays a part i...

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 22/06/2026

🌟 EDITOR'S CHOICE & Open Access! 🔓 The human endometrium regenerates monthly, but this is linked to pathologies like endometriosis. This new review by Subramaniam et al. unpacks the somatic mutation landscape & the need for new in vitro models. 📖 Read: academic.oup.com/molehr/artic...

academic.oup.com

Somatic mutations in endometrial epithelium: biological insights and emerging in vitro models

Abstract. The human endometrium is a complex, dynamic, and poorly understood tissue involving monthly cyclical regeneration likely from adult stem/progenit

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 19/06/2026

🗞️ EXTRA, EXTRA! Molecular Human Reproduction (MHR) has officially reached a new Impact Factor of 4.2 in the JCR 2026! 📈✨ Huge THANKS to our authors, reviewers, ed board & readers! 👏 Check our new cover 👇 & consider MHR for your next submission!

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NU Duncan Lab @nuduncanlab.bsky.social · 15/06/2026

Congratulations to Dr. Aubrey Converse and team for our latest Duncan Lab publication on the post-reproductive ovary which was selected as Editor's Choice in Molecular Human Reproduction! @mhr-reprodsci.bsky.social pubmed.ncbi.nlm.nih.gov/42271623/

pubmed.ncbi.nlm.nih.gov

The post-reproductive ovary shifts from a reproductive to an immune-like organ - PubMed

Reproductive aging in females is characterized by the irreversible depletion of ovarian follicles, yet the structure and function of the post-reproductive ovary remain poorly defined. Using paired his...

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 17/06/2026

Wednesdays are for meeting the minds behind MHR! 🌟 Kicking off our new series is Associate Editor Elle Roberson 👋 👩‍🔬 Asst. Prof at CU Anschutz studying endometrial remodeling & pregnancy success. 🤝 Board: bit.ly/MHR_Board 📝 Submit: bit.ly/MHR_Submissions #MHR #ReproductiveBiology

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 15/06/2026

🌟 Happy Monday! This week's #MHR Editor’s Choice dives into the future of reproductive biology. How can we better understand early human development and improve IVF/ART success rates? Enter: stem cell-based embryo models. 🧫👇 🔗 lnkd.in/eCgDgFGz

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 12/06/2026

Reimagining the post-reproductive landscape. ✨ New data in MHR challenges the dogma that ovaries go "defunct" post-menopause. Instead, they undergo a cellular renaissance, transitioning into an active immune identity. A new paradigm for longevity. 🔬 pubmed.ncbi.nlm.nih.gov/42271623/

pubmed.ncbi.nlm.nih.gov

The post-reproductive ovary shifts from a reproductive to an immune-like organ - PubMed

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 08/06/2026

🌟 Spotlight on the Future of Reproductive Science! Following Friday's paper on placental stress, we're highlighting Rona Karahoda in our Early Career Innovator Series (ECIS)! 🔬 Learn about her work on the human placenta in the panel below 👇 🔗 lnkd.in/djAeTBm6 #Placenta #WomenInSTEM

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 05/06/2026

🔬 Friday's paper in MHR! How do high glucose 🩸, LPS 🦠, & metformin 💊 impact the human placenta? A new study reveals distinct stimulus-specific signatures in placental lipid metabolism & inflammatory signaling. 📖 Read here: academic.oup.com/molehr/artic... #Placenta #ESHREjournals #WomensHealth

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Metabolic, microbial, and pharmacological stimuli elicit distinct lipidomic and cytokine responses in the human placenta

Abstract. The placenta integrates metabolic and immune functions essential for fetal development, and disruptions in lipid metabolism and inflammatory sign

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 02/06/2026

📣 New #OpenAccess paper in MHR! How does SARS-CoV-2 gain entry to the placenta? Pinatel, Vaillancourt & colleagues show that infection of human trophoblasts relies on a non-canonical endosomal pathway, rather than the standard ACE2/TMPRSS2 route. 🔗 academic.oup.com/molehr/artic... #COVID19

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Validate User

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 25/05/2026

🌟 Proud to name Dr. Min (Mia) Yang (UW) as our 2025 Early Career Innovator! 🥇 Don't miss her presenting her fascinating marmoset model research at the MHR Symposium, July 7 at #ESHRE2026. 🔬 👇 Could YOU be our 2026 winner? Apply now: 🔗 lnkd.in/djAeTBm6 @ESHRE #ECISaward

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 22/05/2026

📢 New paper in #MHRJournal! 🔬 A study by Carine Munaut at GIGA-ULiège explores the S1P signaling pathway in an #adenomyosis mouse model. S1P modulation decreased tissue invasion & altered uterine immune cells, showing promise for new therapies! 🧬 👉 academic.oup.com/molehr/artic...

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Stage-dependent sphingosine-1-phosphate pathway modulation as a therapeutic strategy in a murine model of adenomyosis

Abstract. Adenomyosis is characterized by chronic inflammation, myometrial remodeling, and subfertility, yet therapeutic options that preserve reproductive

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 20/05/2026

🔬 New Research Alert in MHR! We are exploring how hormonal dynamics affect endometrial receptivity in endometriosis-associated infertility. A new study links aberrant PGR expression with ESR1 in the endometrium. 🔗 Read the full open-access paper: academic.oup.com/molehr/artic... 🧵👇

academic.oup.com

Aberrant progesterone receptor (PGR) expression is associated with estrogen receptor 1 (ESR1) expression in the endometrium from infertile women with endometriosis

Abstract. Estrogen receptor 1 (ESR1) and progesterone receptor (PGR) are essential regulators for endometrial receptivity and embryo implantation. Their ex

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 18/05/2026

Publish your original research in MHR’s Early Career Innovator Series and compete for the MHR Award! 🏆 The winner gets an all-expenses-paid trip to present at the next ESHRE Annual Meeting. Read the criteria and submit: academic.oup.com/molehr/pages...

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MHR Early Career Innovator Series

MHR is pleased to announce that, throughout 2024 and 2025, our Early Career Innovator Series has gone from strength to strength. As a result, this initiative wi

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 12/05/2026

🔬 New in MHR! Could the liver protein ORM2 hold the key to new #PCOS treatments? Xu et al. show that while Orm2 KO worsens ovarian pathology, recombinant ORM2 supplementation improves ovarian morphology & Ucp1 expression! 💡 📖 Read the full study: academic.oup.com/molehr/artic... #MHRJournal #ESHRE

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Orosomucoid 2 improves reproductive phenotypes in a mouse model of PCOS induced by letrozole under high-fat diet conditions

Abstract. Polycystic ovary syndrome (PCOS) is the most common reproductive endocrine disorder among women of reproductive age. It is characterized by exces

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 08/05/2026

🔬 Is the embryo's "blueprint" set before the first division? New research in @MolHumReprod by Thomas Nolte & Michele Boiani’s team shows the oocyte isn't a blank slate. Sperm entry site & ooplasm distribution dictate the fate of the first blastomeres. 🧬 🔓 Open Access: lnkd.in/eGVs6_BM

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 06/05/2026

We love seeing complex biology beautifully mapped out! 🧬✨ If you are interested in reproductive medicine, you need to check out our latest Editor's Choice! Professor Fauser reviews the incredible journey of AMH. It’s fully OA, so dive right in with your morning coffee: doi.org/10.1093/mole...

doi.org

Developing anti-Müllerian hormone as an ovarian reserve biomarker

Abstract. The first anti-Müllerian hormone (AMH) radioimmunoassay became available for clinical use in the early 2000s. This MHR Legacy Series review discu

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 29/04/2026

🌟 EDITOR'S CHOICE 🌟 How does maternal obesity impact placental vascular development? 🤔 A new review by Ramanlal, James & Boss ( @AucklandUni ) explores how inflammation disrupts angiogenesis & alters fetal growth. 📖 Read: pubmed.ncbi.nlm.nih.gov/41530408/#Pl... #MaternalObesity

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 27/04/2026

Wrapping up a manuscript in reproductive or developmental biology? (And yes, we welcome research across ALL mammalian species, not just human!) 🔬🧬 Why submit to Molecular Human Reproduction (MHR)? Read all 10 reasons here: academic.oup.com/molehr/pages... #ReproBio #DevBio #AcademicPublishing

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10 Reasons to Publish with MHR

MHR is one of the four journals of the European Society for Human Reproduction and Embryology (ESHRE). The journal publishes original research articles, re

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ESHRE @eshre.bsky.social · 08/12/2025

London calling! #ESHRE2026 registration OPEN! What's in store: • Precongress courses • 80+ sessions • Networking & new science • Topics: genomics, AI, ART, immunology, policy & more 📍ExCeL London | 5-8 July 26 ⏰ Abstract deadline: 2 Feb 2026 🔗 www.eshre.eu/ESHRE2026/Re... #HumanReproduction

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MHR | Foundations of Reproductive Science @mhr-reprodsci.bsky.social · 06/01/2026

Ovarian #fibrosis is an emerging factor contributing to ovarian dysfunction, #aging, and female #infertility. Several molecular mechanisms have been investigated to identify the key molecular #pathways driving ovarian fibrosis, including TGF-b/Smad, Wnt/b-catenin and PI3K/Akt pathways.

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