Jason Meyer @meyerlab.bsky.social · 12/09/2026It was a pleasure to attend the IUSM Milestone Ceremony this evening to support Carson and Angie in their White Coat Ceremony! 001
Jason Meyer @meyerlab.bsky.social · 21/08/2026Happy to share my lab’s latest publication led by Jade Harkin, developing a New Approach Methodology platform to explore the combinatorial effects of inflammatory microglia and astrocytes upon retinal ganglion cells, relevant for glaucoma and other optic neuropathies. www.pnas.org/doi/10.1073/...pnas.orgA human pluripotent stem cell triculture platform to elucidate microglial regulation of retinal ganglion cells in neuroinflammation | PNASOptic neuropathies, including glaucoma, are characterized by the progressive degeneration of retinal ganglion cells (RGCs), ultimately leading to i... 083
Reposted by Jason MeyerBob Johnston @bobbyjeyeguy.bsky.social · 25/02/2026I'm excited to share our PNAS paper from 1st author Kasia Hussey. We study how the foveola, the high acuity region of the retina, is patterned by RA and TH. We were surprised to find that cone subtypes appear to convert fates. Our studies are important for AMD sufferers. www.pnas.org/doi/10.1073/...pnas.orgA cell fate specification and transition mechanism for human foveolar cone subtype patterning | PNASIn the central region of the human retina, the high-acuity foveola is notable for its dense packing of green (M) and red (L) cones and absence of b... 32811
Reposted by Jason MeyerBen Sivyer @bensivyer.bsky.social · 04/11/2025We’re hiring! Join the Sivyer Lab at The University of Sydney as a Postdoctoral Research Fellow in Neurodegeneration within the Snow Vision Accelerator, a $50M initiative tackling glaucoma and optic nerve disease. iPSCs, electrophysiology, drug discovery, and gene therapy. 11815
Jason Meyer @meyerlab.bsky.social · 09/09/2025Excited to share the latest paper from our lab! Excellent work from Cátia Gomes and Kang-Chieh Huang! Modeling human retinal ganglion cell axonal outgrowth, development, and pathology using pluripotent stem cell–based microfluidic platformspnas.orgPNASProceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans... 071
Jason Meyer @meyerlab.bsky.social · 22/07/2025Shelby Hetzer, a postdoc in the @meyerlab.bsky.social , crushing it at the Stark Neurosciences Institute Summer Science Symposium! 030
Jason Meyer @meyerlab.bsky.social · 04/07/2025Another exciting pre-print from the lab! This time featuring the work of MSTP student Kaylee Tutrow, we explored the functional consequences of the CX3CR1-V249I polymorphism in human stem cell-derived microglia models! www.biorxiv.org/content/10.1...biorxiv.orgHuman induced pluripotent stem cell-derived microglia with a CX3CR1-V249I genetic variant exhibit dysfunctional phenotypes and modulate neuronal growth and functionThe involvement of microglia in neurodegenerative diseases has drawn increasing attention, as many genetic risk factors are preferentially expressed in microglia. Microglial fractalkine receptor (CX3C... 050
Jason Meyer @meyerlab.bsky.social · 04/07/2025Happy to share a new pre-print from the lab. Here we use human stem cell models to explore how microglia modulate retinal ganglion cells in developmental and neuroinflammation, both directly and in concert with astrocytes. Amazing work from PhD student Jade Harkin! www.biorxiv.org/content/10.1...biorxiv.orgA human pluripotent stem cell tri-culture platform to elucidate microglial regulation of retinal ganglion cells in neuroinflammationOptic neuropathies, including glaucoma, are characterized by the progressive degeneration of retinal ganglion cells (RGCs), ultimately leading to irreversible vision loss. Increasing evidence implicat... 0175
Jason Meyer @meyerlab.bsky.social · 27/06/2025Lab photo (or at least most of the lab) during a tour of the new Medical Education and Research Building at IU School of Medicine. Can’t wait to move in later this year! 070
Jason Meyer @meyerlab.bsky.social · 23/06/2025waiting on IRG scores to post.....🫣media.tenor.coma cartoon of a woman sitting in front of a computerALT: a cartoon of a woman sitting in front of a computer 030
Jason Meyer @meyerlab.bsky.social · 21/06/2025Highly impactful read on the state of Alzheimer's research, and neurodegeneration more broadly. And quite a shout out to Indiana University and the neuroscience programs here at the Stark Neurosciences Research Institute! www.statnews.com/2025/06/17/b...statnews.comBill Gates: I lost my father to Alzheimer’s. But I’m more optimistic than ever about fighting the diseaseBill Gates writes: “We are on the cusp of turning the tide against dementia — which makes this an especially bad time to pull back on research.” 000
Jason Meyer @meyerlab.bsky.social · 31/05/2025Lab lunch to commemorate Kate’s time with the group as she departs for medical school. 020
Reposted by Jason MeyerIUSM SNRI Stem Cell Research Group @iustemcell.bsky.social · 19/05/2025Check out the latest research from the lab of #IUStemCell member Scott Canfield! In this study, they demonstrate that excessive alcohol levels impair the integrity of the blood-brain barrier in human stem cell-derived models, contributing to the onset or worsening of neurological disorders.sciencedirect.comAlcohol diminishes barrier integrity in human stem cell-derived brain microvascular endothelial cells: Role of reactive oxygen speciesThe World Health Organization has linked alcohol consumption to over 200 diseases including neurodegenerative diseases. A dysfunctional blood–brain ba… 001
Reposted by Jason MeyerAnna La Torre @latorrelab.bsky.social · 08/05/2025In this strange times, attending #ARVO2025 has been a breath of fresh air. Inspired by the work, energized by the community and just so so grateful for the chance to spend time with friends and colleagues ❤ 23210
Jason Meyer @meyerlab.bsky.social · 08/05/20255 posters from the Meyer Lab today! Come check out some exciting work from the lab! First is Shruti Patil presenting work on NF1 model of optic pathway gliomas, A0075 460
Jason Meyer @meyerlab.bsky.social · 07/05/2025Check out two awesome posters from the lab this afternoon at 2:00 at #ARVO2025! Cátia Gomes will present work on complement activation in astrocytes for glaucoma (A0433) and Aaron Baker will present work exploring stem cell models of APBB2 gene variant in glaucoma (A0434) 083
Jason Meyer @meyerlab.bsky.social · 07/05/2025Annual gathering of our #AudaciousGoalsInitiative team at @arvoinfo.bsky.social. Lots of exciting work together, and more great ideas to come! #ARVO2025 031
Jason Meyer @meyerlab.bsky.social · 06/05/2025After meeting get-together with the ARPA-H project crew! 030
Jason Meyer @meyerlab.bsky.social · 06/05/2025Looking forward to moving into our new, expanded lab space!!! 040
Jason Meyer @meyerlab.bsky.social · 05/05/2025@meyerlab.bsky.social at the #ARVO2025 Sunday social 0161
Reposted by Jason MeyerIUSM SNRI Stem Cell Research Group @iustemcell.bsky.social · 04/05/2025Congratulations to Feng Guo and his lab for their recent exciting publication in @cp-cellstemcell.bsky.social where they pursue the use of diffusible scaffolds for functional maturation of midbrain organoids! Very cool work!cell.comVascular network-inspired diffusible scaffolds for engineering functional midbrain organoidsGuo and colleagues developed vascular network-inspired diffusible (VID) scaffolds for engineering midbrain organoids, providing a versatile technology for organoid development and therapeutic innovati... 022
Jason Meyer @meyerlab.bsky.social · 01/05/2025That feeling when you get invited to a zoom meeting from a higher up about a “time sensitive potential opportunity” just to show up and find out that the email was meant for someone else and the wrong Jason was autofilled by Outlook 🤣media.tenor.comtwo among us characters are standing next to each other and the word imposter is above themALT: two among us characters are standing next to each other and the word imposter is above them 030
Reposted by Jason MeyerBob Johnston @bobbyjeyeguy.bsky.social · 22/04/2025Wanna grow organoids to understand human retinal development as a research assistant? Wanna help run the lab as a lab manager? The Johnston lab is hiring a research assistant/lab manager. If you are interested, please apply (also please share!): jobs.jhu.edu/job/Baltimor...jobs.jhu.eduResearch TechnologistResearch Technologist 0410
Reposted by Jason MeyerIUSM SNRI Stem Cell Research Group @iustemcell.bsky.social · 10/04/2025Happy to have hosted an informational session from @miltenyibiotec.bsky.social today! Great turnout to hear about some of the latest tools for stem cell research 001
Jason Meyer @meyerlab.bsky.social · 09/04/2025Two days, and two impressive awards for PhD student Kaylee. Yesterday she was named among IU's "Elite 50" graduate and professional students, while today she received the Pao-Lo Yu award for the top graduating student in the Department of Medical and Molecular Genetics. Proud PI moments! 041
Reposted by Jason MeyerIUSM SNRI Stem Cell Research Group @iustemcell.bsky.social · 02/04/2025@iustemcell.bsky.social representing at the Wisconsin Stem Cell Symposium today! #IUStemCell 011
Jason Meyer @meyerlab.bsky.social · 27/03/2025Proud to be in Detroit presenting our work on NF1 at the Gilbert Family Foundation annual meeting of the Next Generation Models Initiative, led by postdoc Shruti Patil. 030
Jason Meyer @meyerlab.bsky.social · 20/03/20252025 Meyer Lab NCAA tournament pool challenge is underway! Let's hope I don't embarrass myself 😉 000
Jason Meyer @meyerlab.bsky.social · 13/02/2025It's @arvoinfo.bsky.social abstract scheduling notification day! Always a thrill to see the excitement from trainees, especially first time attendees and presenters!media.tenor.coma man in a robe is sitting in a chair with his arms in the air and smiling .ALT: a man in a robe is sitting in a chair with his arms in the air and smiling . 080
Jason Meyer @meyerlab.bsky.social · 09/02/2025Moment of positivity last night seeing Sting in concert. During his performance of “If I ever lose my faith” the crowd cheered after the line “you can say I lost my belief in our politicians”. Sometimes things like this help you to realize all is not lost. 040
Jason Meyer @meyerlab.bsky.social · 06/02/2025Looking forward to seeing a bunch of great glaucoma researchers at this conference! 052
Jason Meyer @meyerlab.bsky.social · 17/01/2025Congrats to the latest grad from the @meyerlab.bsky.social, Kaylee Tutrow! Great job on your dissertation defense today! 080
Jason Meyer @meyerlab.bsky.social · 16/12/2024Great description of some of our newest projects as part of a larger collaboration funded by @arpa-h.bsky.social. Excited to see how these projects develop!medicine.iu.eduStudy of optic nerve regeneration in a dish funded by $46 million multi-institutional award aimed at curing blindnessA new multi-institutional project, funded up to $46 million by the Advanced Research Projects Agency for Health (ARPA-H), aims to develop treatments to restore vision through whole eye transplantation... 0121
Jason Meyer @meyerlab.bsky.social · 05/12/2024Excited to play a role as part of a larger, dynamic team here. Along with the Gamm and Bharti labs, we will work to develop nerve bridge grafts combining human stem cells and biomaterials to aid in connectivity between donor eye and recipient optic nerve. A bold goal indeed, but very exciting! 070
Jason Meyer @meyerlab.bsky.social · 05/12/2024A great time visiting with the Fortune Lab at Devers Eye Institute 041
Reposted by Jason MeyerARPA-H @arpa-h.bsky.social · 02/12/2024What if we could cure blindness? Announcing the teams on our THEA program working to enable whole functional eye transplantation to restore vision for the blind and visually impaired. arpa-h.gov/news-and-eve...arpa-h.govARPA-H announces pioneering investments to restore vision to people who are blindThe Advanced Research Projects Agency for Health (ARPA-H) supports transformative research to drive biomedical and health breakthroughs ranging from molecular to societal to provide transformative hea... 095
Jason Meyer @meyerlab.bsky.social · 14/11/2024Making the move to more fully embrace Bluesky - Happy to share the latest publication from my lab, where we leverage an in vitro human stem cell model of the neurovascular unit to identify how the NVU is compromised in glaucoma, particularly with an OPTN normal tension glaucoma genotype.link.springer.comExploring dysfunctional barrier phenotypes associated with glaucoma using a human pluripotent stem cell-based model of the neurovascular unit - Fluids and Barriers of the CNSGlaucoma is a neurodegenerative disease that results in the degeneration of retinal ganglion cells (RGCs) and subsequent loss of vision. While RGCs are the primary cell type affected in glaucoma, neig... 1283