Super excited to finally have this out! We characterized SSR42 as a novel RNA-based regulator of cytotoxicity in S. aureus. It is capable of responding to a host-like environment to activate the leukocidin LukAB and mediate neutriphil interactions. Check it out! journals.asm.org/doi/10.1128/...
journals.asm.org
SSR42 is a novel regulator of cytolytic activity in Staphylococcus aureus | mBio
Staphylococcus aureus is a master pathogen due to its formidable collection of virulence factors. These are tightly controlled by a diverse group of regulators that titrate their abundance to adapt to unique infectious niches. The role of regulatory RNAs ...