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MDSpire News

@mdspirenews.bsky.social
60 followers 19 following 424 posts

The premier global destination for trusted clinical content, breaking news, and educational resources to support healthcare professionals' growth. news.mdspire.com

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MDSpire News @mdspirenews.bsky.social · 06/10/2026
🤖 How can healthcare professionals embrace AI without losing critical thinking? Experts at Cleveland Clinic’s A.I. Summit explored how AI can support learning while preserving reasoning and independent thought. 🔗 Read more: ow.ly/ST8M50ZTXnz #AIinHealthcare
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MDSpire News @mdspirenews.bsky.social · 02/10/2026
Could AI help make health care more accessible and affordable? Jame Abraham, MD, FACP, discusses AI’s potential to expand access, and why clinician education and leadership matter. ow.ly/uq4U50ZT8HX #AIinHealthcare
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MDSpire News @mdspirenews.bsky.social · 01/10/2026
🧠 A new treatment option has entered Parkinson disease care. The FDA has approved tavapadon (Juvmo), a once-daily dopamine agonist that can be used with or without levodopa. 🔗 Learn more: ow.ly/TTlK50ZT94X #ParkinsonsDisease #Neurology #FDA
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MDSpire News @mdspirenews.bsky.social · 30/09/2026
💊AI in drug development is moving from promise to practice. From accelerating manufacturing to improving antibody design, pharma leaders share where AI is delivering results, and why understanding its limits is essential. ow.ly/HX1q50ZT8xP
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Where AI is already paying off in drug development
Pharmaceutical leaders point to faster manufacturing, smarter antibody design, and deeper data analysis.
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MDSpire News @mdspirenews.bsky.social · 29/09/2026
What are the evidence-based essentials every pulmonology clinician should know? From asthma and COPD to pulmonary fibrosis, pulmonary hypertension, and ARDS, MDSpire News highlights 10 key guidelines, trials, therapies, + clinical tools shaping respiratory care. 🔗 Explore: ow.ly/5oFb50ZSFYB
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MDSpire News @mdspirenews.bsky.social · 25/09/2026
💉 FDA approves once-weekly insulin for adults with type 2 diabetes. Four phase 3 trials found insulin efsitora alfa-gobe noninferior for HbA1c reduction vs once-daily basal insulin comparators. Read more: ow.ly/hMoS50ZRrx9 #Diabetes #FDA
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MDSpire News @mdspirenews.bsky.social · 24/09/2026
🦠 Antimicrobial resistance is a moving target. How should treatment keep pace? IDSA has updated its guidance for antimicrobial-resistant gram-negative infections, incorporating newer therapies and evolving evidence across six major pathogen groups. 💊 Explore the updates: ow.ly/wBMa50ZQblC
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MDSpire News @mdspirenews.bsky.social · 23/09/2026
🏥 How can hospitals strengthen #sepsis care? A multidisciplinary panel has identified 5 high-priority strategies focused on the infection-related aspects of sepsis care, from faster diagnostics and antibiotic delivery to antimicrobial stewardship. Explore the 5 priorities: ow.ly/T8HP50ZQbe9
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MDSpire News @mdspirenews.bsky.social · 22/09/2026
📢 The FDA has updated the label for sotatercept following new data. In adults recently diagnosed with pulmonary arterial hypertension, adding sotatercept to background therapy reduced the risk of clinical worsening events by 76% compared with placebo in the HYPERION trial. ow.ly/ZCkq50ZQaZN
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MDSpire News @mdspirenews.bsky.social · 18/09/2026
🤖 Change control plans are becoming more common for FDA-cleared radiology AI devices, but how transparent are they? A review found public documentation often lacked details on postmarket performance monitoring. 📊 Read more: ow.ly/UyT850ZOFlZ
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FDA change plans in radiology AI
Investigators examined adoption and public documentation of change control plans for FDA-cleared radiology AI devices.
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MDSpire News @mdspirenews.bsky.social · 17/09/2026
Healthcare is undergoing an AI-driven “epistemic shift.” Pete Clardy, MD, PhD, of Google for Health explores how rapidly advancing AI could reshape clinical decision-making and medical expertise. Read more from his Cleveland Clinic AI Summit keynote ow.ly/kpxr50ZKusB
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Google clinical leader on health care’s AI ‘epistemic shift’
“AI is in its infancy. It’s as bad as it will ever be right now, and the rate of change is remarkable.”
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MDSpire News @mdspirenews.bsky.social · 14/09/2026
As AI takes on more routine work, the physician’s role may shift toward what technology cannot easily replicate: clinical judgment, navigating uncertainty, empathy, and complex decision-making. Learn more from Cleveland Clinic's AI Summit: ow.ly/4eh950ZKuow
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AI poised to reshape care
“This is really a unique time in our careers to see such a large change in technology.
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MDSpire News @mdspirenews.bsky.social · 12/09/2026
Twenty-five years after September 11, long-term monitoring and care continue to support WTC responders and survivors. Clinicians report improved outcomes, while gaps remain in mental health and sleep disorder care. Read more: ow.ly/8bKt50ZMzqI #September11 #WTCHealthProgram
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WTC Health Program extends lives, but care gaps remain
Long-term monitoring, trusted clinical relationships and no-cost treatment have improved outcomes, while mental health and sleep disorders continue to test the system.
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MDSpire News @mdspirenews.bsky.social · 11/09/2026
Twenty-five years after September 11, clinicians continue to see evolving health effects among WTC responders and survivors. As this population ages, cognitive decline is becoming an important area of research and care. Read more: ow.ly/S1Em50ZMzmk #September11 #WTCHealthProgram
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MDSpire News @mdspirenews.bsky.social · 09/09/2026
As AI takes on more routine work, what happens to the skills clinicians build through repetition? Experts at Cleveland Clinic's AI Summit for Health Care Professionals examine de-skilling, automation bias, training, and the future of clinical expertise. Learn more: ow.ly/ZjGy50ZKulB
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What happens to clinical skills when AI does the routine work?
“The need to be extra vigilant when you're reviewing something versus doing it from scratch can be a real problem.”
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MDSpire News @mdspirenews.bsky.social · 08/09/2026
🦠 Nearly half of hospitalized COVID-19 patients had detectable reactivation of at least one chronic virus during acute illness, according to a new study. The findings highlight potential markers for further investigation. 🔗 ow.ly/fCCg50ZKuiz #COVID19 #Virology #Pathology
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MDSpire News @mdspirenews.bsky.social · 04/09/2026
👁️ A first-in-human stem cell trial has improved vision in patients with aniridia-related keratopathy, with patients gaining an average of 24 ETDRS letters following treatment. 🔗 ow.ly/alla50ZIiBJ #StemCells #Ophthalmology
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MDSpire News @mdspirenews.bsky.social · 03/09/2026
🧫 Clinical decision support reduced respiratory culture use by 16% across 15 US pediatric intensive care units, without evidence of adverse patient outcomes. 🔗 Read more: ow.ly/Goel50ZIizh #Microbiology #DiagnosticStewardship
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MDSpire News @mdspirenews.bsky.social · 02/09/2026
🧬 Could glycosylation unlock new cancer biomarkers? Catherine Bladen explores how advances in glycoscience are revealing new insights into tumor biology, biomarker discovery and potential therapeutic targets. 🔗 ow.ly/1zij50ZIiv3 #CancerResearch #Biomarkers
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MDSpire News @mdspirenews.bsky.social · 27/08/2026
💬 Can empathy be trained? A study involving 303 healthcare professionals put simulation-based training to the test and found a significant increase in empathic attitudes after the program. Explore the findings: ow.ly/97QP50ZF5v1 #Healthcare #MedicalEducation #PatientCare
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MDSpire News @mdspirenews.bsky.social · 26/08/2026
🍺 Beer + HIIT? Researchers put the combination to the test. The BEER-HIIT study asked whether moderate alcohol consumption affects heart rate variability adaptations after 10 weeks of high-intensity training. 👀 See what they found: ow.ly/lZpj50ZF49t #Cardiology #HIITS
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MDSpire News @mdspirenews.bsky.social · 20/08/2026
🔬 A new view on complex skull base surgery? Initial experience using the ORBEYE™ 4K 3D exoscope for the combined petrosal approach in petroclival meningiomas showed encouraging visualization and early outcomes. 🔗 Read more: ow.ly/O6zL50ZBnKU #Neurosurgery
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MDSpire News @mdspirenews.bsky.social · 13/08/2026
🧪 A new screening platform could broaden molecular glue discovery. Researchers identified a glutathionylation-activated molecular glue that recruits DCAF11 to degrade DDX18, revealing a new mechanism of targeted protein degradation. 🔗 ow.ly/Vv9N50ZysN6 #DrugDiscovery
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New Screen May Expand Molecular Glue Discovery
A multiplexed screening platform identified a glutathionylation-activated DCAF11 molecular glue, revealing a previously unrecognized mechanism of targeted protein degradation.
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MDSpire News @mdspirenews.bsky.social · 12/08/2026
🎯 Could AI speed up breast cancer treatment planning? Calvin Chao of Artera discusses an FDA-cleared digital pathology tool that can provide risk stratification for early-stage HR+/HER2− breast cancer in about an hour. 🔗 ow.ly/HCPq50ZysJu #BreastCancer #DigitalPathology
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A Faster Path to Breast Cancer Prognosis
An FDA-cleared AI tool offers shorter turnaround times and supports precision oncology
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MDSpire News @mdspirenews.bsky.social · 06/08/2026
👃 Does smell loss tell us more than we think? A new meta-analysis involving more than 187,000 patients explored the relationship between olfactory impairment and depression, uncovering some surprising differences depending on how smell loss is measured. Read the findings: ow.ly/OJR750ZvHJJ
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Is Smell Loss Tied to Depression?
A meta‐analysis found consistent associations between self‐reported olfactory impairment and depression, whereas objectively measured impairment was linked to depression primarily among older adults and patients with anosmia.
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MDSpire News @mdspirenews.bsky.social · 04/08/2026
Could adjuvant ensartinib change the treatment landscape for resected ALK-positive #NSCLC? New phase 3 ELEVATE trial results published in NEJM highlight improved disease-free survival after surgery. 🔗 ow.ly/8RmT50ZvHE7 #LungCancer #Oncology
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Postsurgical Ensartinib in ALK-Positive NSCLC
Adjuvant ensartinib may represent a new therapeutic strategy in completely resected disease.
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MDSpire News @mdspirenews.bsky.social · 03/08/2026
A new name. The same trusted partner. Today, Conexiant News officially becomes MDSpire News. While the name is changing, our trusted editorial team, clinical audiences, and partnership opportunities remain the same. Learn more: conexiant.com/introducing-mdspire-n… #MDSpireNews
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MDSpire News @mdspirenews.bsky.social · 16/07/2026
High procalcitonin after 7 days of antibiotics... should treatment continue? A new BALANCE trial analysis found no evidence that extending therapy from 7 to 14 days improved outcomes in this subgroup. Read more: ow.ly/kihf50ZnNNE
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Does High PCT Warrant Longer Therapy?
In a planned BALANCE analysis, elevated day 7 procalcitonin was associated with higher mortality, but the small subgroup analysis found no evidence that extending antibiotics from 7 to 14 days improved outcomes.
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MDSpire News @mdspirenews.bsky.social · 15/07/2026
"Natural" doesn't always mean safe. A tragic new case report describes a 7-year-old who developed fatal acute liver failure after taking an herbal remedy for jaundice that was found to contain arsenic and lead. Read more: ow.ly/ejYe50ZnMVn #MedTwitter #PatientSafety #Toxicology
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Medical Oddities: Natural Doesn't Always Mean Safe
From the gym to the kitchen to romance, these studies challenge everyday assumptions.
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MDSpire News @mdspirenews.bsky.social · 14/07/2026
Could GLP-1 receptor agonists improve rotator cuff repair outcomes? A new study found preoperative GLP-1 use was linked to fewer revisions in patients with obesity, without increasing short-term complications. Read more: ow.ly/miSO50ZmjnB #Orthopedics #GLP1
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Do Revisions in Rotator Cuff Repair Decline With GLP-1 Use?
Preoperative use was associated with fewer revisions and no increase in short-term complications among patients with obesity, although benefits appeared concentrated in select subgroups.
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MDSpire News @mdspirenews.bsky.social · 13/07/2026
👁️ Where are patients being lost in the diabetic retinopathy care pathway? A US systematic review identified major gaps in screening, diagnosis awareness, referral, and follow-up, with more than half of patients unaware they had diabetic retinopathy. Read more: ow.ly/YXkf50Zmjav
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Diagnosis Gaps Mark Retinopathy Care
A US systematic review found substantial losses across diabetic retinopathy screening, diagnosis awareness, referral, and follow-up.
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MDSpire News @mdspirenews.bsky.social · 10/07/2026
🤖 Can AI help speed up urine drug test interpretation? A new study found an AI-assisted workflow maintained high interpretive accuracy while reducing laboratory sign-out time by up to 51% in a supervised clinical setting. Read more: ow.ly/VSQW50Zmj0X
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Can AI Aid Urine Drug Test Sign-Outs?
Researchers reported that an artificial intelligence workflow maintained high interpretive accuracy while reducing urine drug test sign-out time in a supervised clinical laboratory setting.
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MDSpire News @mdspirenews.bsky.social · 02/07/2026
FDA expands approval of CASGEVY. The CRISPR/Cas9 gene-edited therapy is now indicated for patients aged 2 years and older with sickle cell disease and recurrent vaso-occlusive crises or transfusion-dependent beta thalassemia. Read more: ow.ly/xmSa50ZjG8i #GeneTherapy #CRISPR #Hematology
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MDSpire News @mdspirenews.bsky.social · 26/06/2026
Could lipid metabolism play a role in psoriasis risk? A Mendelian randomization analysis found genetically predicted triglyceride levels were associated with higher odds of psoriasis, while total fatty acid levels were not. Read more: ow.ly/iJW350ZfAxr #Psoriasis #Dermatology
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Triglycerides Linked to Psoriasis Risk
Genetically predicted triglyceride levels were associated with higher odds of psoriasis, while genetically predicted total fatty acid levels were not, in a two-sample Mendelian randomization analysis.
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MDSpire News @mdspirenews.bsky.social · 25/06/2026
A world-first HIV-positive-to-HIV-positive lung transplant has been reported by NYU Langone Health. The milestone could expand access to lifesaving organs for people living with HIV. Read more: ow.ly/fqhV50ZfeEp #Transplantation #HIV
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First HIV-Positive-to-HIV-Positive Lung Transplant Reported
The procedure was performed under a HOPE Act research protocol at an NYU Langone Health center the institution said is among the limited number of US transplant centers equipped and approved to perform HOPE lung transplants.
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MDSpire News @mdspirenews.bsky.social · 23/06/2026
☀️ Sunscreen misinformation may be rare on TikTok, but it gets attention. A new analysis found that while most highly viewed sunscreen content promoted sunscreen use, videos questioning sunscreen safety generated significantly more likes, shares, and comments. Read more: ow.ly/elfb50ZfeLS
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Sunscreen Myths Draw TikTok Engagement
Health-related critiques of sunscreen were uncommon, but videos containing critique drew more audience interaction than promotion-only videos.
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MDSpire News @mdspirenews.bsky.social · 22/06/2026
🥚 Can introducing egg earlier help prevent egg allergy? A population-based Australian study found lower rates of egg allergy following a shift toward earlier egg introduction, especially among infants with early eczema. Read more: ow.ly/9r6a50Zfeqz #FoodAllergy #Pediatrics
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Earlier Egg Intake Linked to Less Allergy
Population-based data suggest uptake of updated feeding recommendations coincided with modest declines in egg allergy prevalence, particularly among infants with early eczema.
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MDSpire News @mdspirenews.bsky.social · 16/06/2026
As measles cases rise in parts of the US, renewed attention is being placed on vaccination rates, waiver policies, + public health communication. This report examines how states are navigating vaccine exemptions amid growing concerns about outbreaks . Read more 👇 ow.ly/tNJn50Z7W8c
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Measles Renews Focus on Vaccine Waivers
“And when one of these measles cases ends up in a low-immunization community, that's when the ember really has a chance to expand and become a wildfire.”
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MDSpire News @mdspirenews.bsky.social · 12/06/2026
From household chores to sleep deprivation, the body keeps score. This week's *Side Effects* looks at how bariatric surgery may improve daily functioning for decades and how saliva could reveal the effects of an all-nighter. Read more: ow.ly/tkFj50Z7EQo #MedicalResearch #SleepScience
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Side Effects: The Body Keeps Score
Turns out biology tracks more than we thought — from a spit test that reads your all-nighter to a surgical outcome that still shows up in household chores two decades later. Plus: habits aren't built gradually. They snap.
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MDSpire News @mdspirenews.bsky.social · 10/06/2026
Genetics, clinical factors, and social determinants all play a role in neurodevelopment after congenital heart surgery. New research highlights the importance of ongoing developmental surveillance for children with congenital heart disease. Read more: ow.ly/tLnY50Z7EMz #CHD #Pediatrics
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Early Neurodevelopmental Outcomes in Pediatric Congenital Heart Disease
In a multicenter registry study, genetic diagnoses were associated with substantially lower cognitive, language, and motor scores; while birth weight, surgical timing, hospitalization burden, and caregiver education were also associated with outcomes.
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MDSpire News @mdspirenews.bsky.social · 09/06/2026
Could proteomics help refine who gets screened for lung cancer? A blood-based risk model using 13 circulating protein biomarkers improved short-term lung cancer risk assessment in an international validation study. Read more: ow.ly/2XYX50Z7Esi #LungCancer #Proteomics
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Can Proteomics Refine Lung Screening?
Proteomic biomarkers improve short-term lung cancer risk assessment.
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MDSpire News @mdspirenews.bsky.social · 05/06/2026
What if one of the most effective public health interventions isn't a drug or vaccine, but a house? A new study suggests improved housing could significantly reduce childhood infections and support healthier development. Read more: ow.ly/ubru50Z7CEQ #GlobalHealth #PublicHealth
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Medical Oddities: Can a Home Be Preventive Care?
This week’s medical plot twists involved ants, architecture, and auditory hallucinations.
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MDSpire News @mdspirenews.bsky.social · 04/06/2026
Could immigration restrictions worsen healthcare shortages? A new study found physicians and nurses from countries affected by the 2025 immigration ban are more likely to work in underserved US communities. Read more: ow.ly/uK9H50Z7BP2 #HealthPolicy
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How Many US Clinicians Come From Banned Countries?
Counties with at least one clinician from a banned country were more likely to be designated primary care shortage areas.
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MDSpire News @mdspirenews.bsky.social · 03/06/2026
New research suggests oral cancers arising without smoking, alcohol use, or HPV may follow entirely different biological pathways. Researchers identified distinct mutational and immune-response patterns in these “no-identified risk factor” tumors. Read the full story: ow.ly/nWbO50Z58sE
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Mutational Signatures May Define Oral Cancers
Researchers identified endogenous mutational and immune-response patterns in oral cancers arising without exposure to tobacco, alcohol, or human papillomavirus infections.
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MDSpire News @mdspirenews.bsky.social · 01/06/2026
What’s hiding in the dust around us? Researchers analyzing vacuum dust from schools, offices, dorms, & daycares detected 54 viruses, including SARS-CoV-2, influenza A, RSV, norovirus, and rhinoviruses. The findings could reshape how we monitor outbreaks indoors. Read on: ow.ly/5pbL50Z58po
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Medical Oddities: Something Viral is Lurking in the Dust
Everyday things like yawns, tea, dust, and kimchi suddenly look medically important.
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MDSpire News @mdspirenews.bsky.social · 29/05/2026
A new prospective study found patients with preoperative vitamin D deficiency had higher pain scores and greater opioid use after mastectomy, including more than 3x the odds of moderate to severe pain within 24 hours. Read more about the findings 👇 ow.ly/QTel50Z58ml #BreastCancer
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Postop Pain Differs by Vitamin D Status
Patients with preoperative vitamin D deficiency had higher postoperative pain scores and opioid use after mastectomy, including more than triple the odds of moderate to severe pain within 24 hours of surgery.
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MDSpire News @mdspirenews.bsky.social · 28/05/2026
A new multicenter cohort study sheds light on treatment patterns in cutaneous #CrohnsDisease. a rare and often under-recognized skin manifestation of IBD. Discover their insights: ow.ly/1qwO50Z58iQ #IBD #RareDiseases
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Biologics Commonly Used in Cutaneous Crohn's Disease
Retrospective multicenter cohort highlights genital-predominant presentation patterns and frequent combination therapy use in cutaneous Crohn's disease.
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MDSpire News @mdspirenews.bsky.social · 22/05/2026
Could asthma & allergic rhinitis be linked to Parkinson’s disease risk? A study of more than 5 million adults found modestly higher Parkinson’s disease incidence among patients with allergic airway diseases. Read more: ow.ly/oIn850Z2AG0 #ParkinsonsDisease #NeurologyResearch
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Asthma, Rhinitis Tied to Parkinson's Risk
A nationwide Korean cohort study found modestly higher Parkinson's disease incidence among patients with asthma or allergic rhinitis, with stronger associations observed among patients with greater allergic disease burden.
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MDSpire News @mdspirenews.bsky.social · 21/05/2026
A new Senate investigative report details internal communications, VAERS data, and CDC case reviews related to myocarditis and pericarditis in adolescents and young adults following mRNA COVID-19 vaccination. Read the latest 👇 ow.ly/9n3B50Z2Aq8 #Cardiology
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Senate Report Details Early Myocarditis Signals After COVID-19 Vaccination
Investigative report cites internal communications, VAERS data, and CDC case reviews describing myocarditis and pericarditis reports in adolescents and young adults after mRNA COVID-19 vaccination.
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MDSpire News @mdspirenews.bsky.social · 19/05/2026
🚨 FDA approves Baxfendy for resistant hypertension. The first aldosterone synthase inhibitor approved for adults whose blood pressure remains uncontrolled despite multiple medications showed nearly a 10 mmHg placebo-adjusted reduction in systolic BP in phase 3 data. 🔗 ow.ly/6MGR50Z1vGN
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FDA Approves Baxdrostat for Resistant Hypertension
Phase 3 findings support the oral therapy in adults with persistent blood pressure elevation despite multidrug treatment.
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