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Reposted by Michael J. Young

Felix Pahmeier @fpahmeier.bsky.social · 19/02/2025

Happy to finally see this study published, a great collaboration between academic, government and industry labs! We show that CCHFV GP38 can induce vascular leak and that this can be prevented by protective but not virus-neutralizing antibodies! www.science.org/doi/10.1126/...

science.org

Antibodies targeting Crimean-Congo hemorrhagic fever virus GP38 limit vascular leak and viral spread

Glycoprotein GP38-specific antibodies reduce viral dissemination and GP38-mediated vascular leak in Crimean-Congo hemorrhagic fever virus infection.

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