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Matt Bashton

@mattbashton.bsky.social
529 followers 1.7K following 28 posts

Associate Prof in Computational Biology at Northumbria University, Newcastle, UK. Structural and High Throughout Sequencing Bioinformatics, Protein Domains, Pandemic Preparedness.

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Matt Bashton @mattbashton.bsky.social · 06/03/2025
This week at @northumbriauni.bsky.social we launched our new #HPC cluster Higgs, having been involved in shaping this project from the outset it's nice to see it finally come to fruition with our partners #Logicalis and #Lenovo. l'm looking forward to all the research our new cluster will enable.
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Matt Bashton @mattbashton.bsky.social · 20/11/2024
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Matt Bashton @mattbashton.bsky.social · 20/11/2024
Been exploring some of the breathtaking John Portman architecture in Atlanta while at #SC24
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Matt Bashton @mattbashton.bsky.social · 20/11/2024
Nice to see this CPS-1, duel CPU 68000/Z80 set-up at #SC24, it's all about those custom chips too! #retrogaming
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Matt Bashton @mattbashton.bsky.social · 14/11/2024
Interestingly if we look at promiscuous superfamilies' (those binding multiple ligands) we find they can fall into "generalised" - binding a wide range of chemically diverse ligands or "specialised" - binding some very chemically similar ligands, categories.
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Matt Bashton @mattbashton.bsky.social · 14/11/2024
This the work of my PhD student Matt Crown, one of the nice things he did was this t-SNE plot of cognate ligand space within the PDB, in which we see some nice clusters of related compounds.
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