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Mark Bartlett @markyb-gene.bsky.social · 01/02/2025

Great move that funding going from #genetics e.g. @23andme.bsky.social to #genomics however the team involved and backers sounds like the rise of #DTCeugenics

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Mark Bartlett @markyb-gene.bsky.social · 01/02/2025

Great to see industry move from #genetics to #genomics! Shame that it is being used to push trait and behavioural genetics. Could this be the birth of #DTCeugenics? www.genomeweb.com/informatics/...

genomeweb.com

Nucleus Genomics Raises $14M in Series A Financing

The firm aims to use the new funding to launch heritable disease and personalized drug metabolism genetic tests.

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Mark Bartlett @markyb-gene.bsky.social · 31/01/2025

Yeah, that's what we request if someone wants to send us data. fastq files all the way!

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Mark Bartlett @markyb-gene.bsky.social · 31/01/2025

The barrier I see is not just technical (cost of moving data) but having clear sets of quality standards and log of bioinformatics tools used for analysis so that we can be clear about limitations. We store this all as well!

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Mark Bartlett @markyb-gene.bsky.social · 31/01/2025

I agree, @genomicsengland.bsky.social are a real asset to the UK's #genomic infrastructure. Also the NHS Genomic Medical Service are running a Connectathon next week which we are participating in.

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Mark Bartlett @markyb-gene.bsky.social · 31/01/2025

Would love to. Current focus is to work with enough providers to continue building a service which provides actual value for health. Open to ideas on how we could collaborate and support doing this with minimal resource

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Mark Bartlett @markyb-gene.bsky.social · 30/01/2025

We have and we will transfer data to wherever the data subject wants. Do you have someone in mind?

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Mark Bartlett @markyb-gene.bsky.social · 30/01/2025

Interested to know whether the Exec Director of Science for Our Future Health (the UKs flagship genetic panel testing project) thinks genomics is useful? (Yes I do believe there is a difference between #genetics and #genomics) Get to the main stage #FOG2025

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Mark Bartlett @markyb-gene.bsky.social · 30/01/2025

Day1 was mixed - historical foundation of #Eugenics, 1.3million #adversedrugreactions and sobering character assignation of #polygenicriskscores. on the other side @nhsgms.bsky.social seem to be taking data seriously. What do we think day 2 has in store? #FOG2025

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Mark Bartlett @markyb-gene.bsky.social · 30/01/2025

Shocked, I spent a whole 24 hours with fellow #omic enthusiasts and not one has signed up for the highest quality, low cost, analysed whole #genome sequencing #WGS service available in Europe. #FOG2025 come find me today if you want in!

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Mark Bartlett @markyb-gene.bsky.social · 29/01/2025

Prof. David Curtis @ugiatucl.bsky.social shared how #PolygenicRiskScores originated as way to justify a failed schizophrenia #GWAS, reminded me of @adamrutherford.bsky.social earlier talk. It is vital to understand the history of our beloved #genomic techniques. #FOG2025

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Mark Bartlett @markyb-gene.bsky.social · 29/01/2025

It was great to see Prof Aroon Hingorani from @ugiatucl.bsky.social delving into the evidence for use of #polygenicriskscores. It's not optimistic. Check out resources below. #FOG2025

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Mark Bartlett @markyb-gene.bsky.social · 29/01/2025

This is insane...... 1.3m adverse drug reactions have been reported in the UK. However of these 75%...... 3 out of 4 are due to medications which are associated with just 3 #genes! Why do we keep prescribing with out #pharmacogenomics #FOG2025

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Mark Bartlett @markyb-gene.bsky.social · 29/01/2025

Very eloquent presentation by Prof. Matt Brown CSO @genomicsengland.bsky.social Whole #Genome Data #WGS is the only way we can sustainably integrate #pharmacogenomics cost effectively. Completely agree.

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Mark Bartlett @markyb-gene.bsky.social · 12/12/2024

Standing room only at Ensuring the @nhsgms.bsky.social #delivers an #equitable #genomic testing offer. Great to see so much interest!

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Mark Bartlett @markyb-gene.bsky.social · 12/12/2024

Resounding want for better, braver #genetic data sharing #NHSGenomics2024

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Mark Bartlett @markyb-gene.bsky.social · 12/12/2024

Kicking off with NHS Chief Executive, Amanda Pritchard. The top level support for @nhsgms.bsky.social to deliver a more efficient, more hopeful @nhsengland.bsky.social. #equity should be at the heart of new initiatives.

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Mark Bartlett @markyb-gene.bsky.social · 12/12/2024

Looking forward to joining @nhsgms.bsky.social for #NHSGenomics2024. Come say hi if you want to talk #wholegenome #valuemaximisation or #reanalysis using #CloudGenomics (What a first post on @bsky.app!)

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