iiinova — where your digital self keeps evolving

Reposted by Maria Gubbiotti, MD,PhD

Liz Hileman @lizhilemanphd.bsky.social · 24/10/2025

Abstract deadline approaching quickly (Nov 7, 2025) for the international #cancerneuroscience #symposium happening in Feb 2026!! Check out registration (SO CHEAP for 3 days!), abstract, and award details here: mdanderson.cloud-cme.com/course/cours...

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Maria Gubbiotti, MD,PhD @mariagoobs.bsky.social · 22/10/2025

Come join us in pathology at @mdanderson.bsky.social ! A great opportunity with a fun and dynamic group! 🔬 #pathsky

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Maria Gubbiotti, MD,PhD @mariagoobs.bsky.social · 02/10/2025

October 1st, the start of one of my favorite months! One of my friends in IT made me this 3D printed brain 🧠 the spooky candies were a nice touch 🎃 #pathsky

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Reposted by Maria Gubbiotti, MD,PhD

PathologyOutlines.com @pathologyoutlines.bsky.social · 25/06/2025

Image of the Week! Submitted by: Gabrielle Yeaney, M.D. Directory Profile: www.pathologyoutlines.com/directory/ga... Subspecialty: Neuropathology Diagnosis: Normal pineal gland #Pathology #PathologyOutlines #NeuroPath #PathSky

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Maria Gubbiotti, MD,PhD @mariagoobs.bsky.social · 13/06/2025

Dural-based mass with dural tail Negative for SSTR2, no evidence of STAT6 fusion, and strong CD56 staining GLI1 amplification present 🧠 take home point: GLI1-altered mesenchymal tumors can occur in the CNS and radiologically mimic meningioma! academic.oup.com/jnen/advance... #pathsky

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Reposted by Maria Gubbiotti, MD,PhD

UT MD Anderson Cancer Center @mdanderson.bsky.social · 09/06/2025

MD Anderson research findings suggest that targeting interactions between some cells around the blood vessels could help make glioblastoma more vulnerable to treatment. Read more: spr.ly/633204H8Uj #OncSky #EndCancer

spr.ly

Targeting cells that form blood vessels in glioblastoma could improve treatment

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Reposted by Maria Gubbiotti, MD,PhD

Caroline Brennan @txbraintrust.bsky.social · 17/04/2025

📣TOMORROW, Friday, April 18, 12 noon CST!📣 Join the Brain Tumor Center of the Cancer Neuroscience Program seminar series! 🧠 We’re talking liquid biopsies in CNS tumors with @MDAnderson.bdky.social pathologist Dr. Leomar Ballester. Login details: Email tpmarin@mdanderson.org

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Maria Gubbiotti, MD,PhD @mariagoobs.bsky.social · 04/04/2025

Superstar surgical pathology fellow Dr. William Mi was recognized with the Award for Clinical Excellence in Professionalism today! Congratulations to him for the well-deserved honor 🔬 #pathsky #medsky @mdanderson.bsky.social

A photo of Dr Mi wearing a white coat on the big screen

Dr Mi shaking hands with the award giver

Two pathologists taking a photo in front of a plant

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Reposted by Maria Gubbiotti, MD,PhD

UT MD Anderson Cancer Center @mdanderson.bsky.social · 19/02/2025

MD Anderson and Texas Children’s Hospital announce a transformational collaboration dedicated solely to pediatric cancer care. This new first-of-its-kind joint venture, which will launch in early 2026, has a single mission: to end childhood cancer. #EndCancer

bit.ly

UT MD Anderson and Texas Children’s Hospital Announce Joint Venture to End Childhood Cancer

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Maria Gubbiotti, MD,PhD @mariagoobs.bsky.social · 11/02/2025

In honor of upcoming Valentine’s Day here is a classic example of rosette-forming glioneuronal tumor. These grade 1 tumors typically show a hotspot mutation in FGFR1 along with PIK3R1 or PIK3CA alterations and are usually found in the fourth ventricle 🌹 ♥️ 🥀 🧠 🔬 #pathsky #neuropath #medsky

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Reposted by Maria Gubbiotti, MD,PhD

AndrewFolpe @folpe-mn-st.bsky.social · 06/02/2025

#PathSky 43F with a solitary lung mass. Relatively circumscribed, nests and interesting micropapillae of lightly eosinophilic epithelioid cells. Negative for everything except TFE3. Dx?

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Reposted by Maria Gubbiotti, MD,PhD

AndrewFolpe @folpe-mn-st.bsky.social · 06/02/2025

This is a clear cell stromal tumor of the lung. They have YAP1::TFE3 fusions, which are also present in YAP1::TFE3-fused hemangioendotheliomas and some pulmonary PEComas. Abbas Agaimy described these. pubmed.ncbi.nlm.nih.gov/33899786/

pubmed.ncbi.nlm.nih.gov

Recurrent YAP1-TFE3 Gene Fusions in Clear Cell Stromal Tumor of the Lung - PubMed

Clear cell (hemangioblastoma-like) stromal tumor of the lung (CCST-L) is a recently described distinctive rare pulmonary neoplasm of unknown histogenesis and molecular pathogenesis. Only 7 cases have ...

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Reposted by Maria Gubbiotti, MD,PhD

Matt Campbell @mjcampbell.bsky.social · 26/01/2025

Palpably unfair act is definitely entering the lexicon #eagles

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Maria Gubbiotti, MD,PhD @mariagoobs.bsky.social · 21/01/2025

Grateful to work with such a fantastic group to learn new things and help our patients the best we can! #pathsky #medsky

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Maria Gubbiotti, MD,PhD @mariagoobs.bsky.social · 19/01/2025

Just like Texas rarely sees snow ❄️, every once in a while you will find a primary tumor of the posterior pituitary so keep it in mind during frozen section analysis! Here is a classic example of pituicytoma showing diffuse nuclear positivity for TTF1 #pathsky #neuropath #medsky 🔬 🧠

Smear preparation showing a fibrillary spindle cell neoplasm

Close up of the prior smear showing fibrillary to feathery cytoplasm and ovoid nuclei

H&E stained permanent section showing a whorled to spindled bland appearing tumor

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Reposted by Maria Gubbiotti, MD,PhD

AndrewFolpe @folpe-mn-st.bsky.social · 08/01/2025

#PathSky 32M with extra-axial, dural-based, frontoparietal mass. Clearly malignant epithelioid cells arranged in cords and nests in a sclerotic background. Looks a lot like a sclerosing epithelioid fibrosarcoma, and it is strongly MUC4-positive. So, we’re done, right?

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Maria Gubbiotti, MD,PhD @mariagoobs.bsky.social · 02/01/2025

Jumping into 2025 with an endolymphatic sac tumor, a VHL-associated neoplasm arising in the posterior petrous bone of the ear #pathsky #eqbsky #neuropath #entpath

H&E stained section of a papillary neoplasm with bland cells arising within the ear

Higher power view of a papillary neoplasm stained with H&E

A bay horse jumping an oxer in a grass field with a blue sky overhead

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Maria Gubbiotti, MD,PhD @mariagoobs.bsky.social · 24/12/2024

Aired our grievances yesterday for Festivus and now enjoying the magic of Christmas Eve 🎄🎁🦄 #eqbsky

A bay horse and a person wearing a Buc-ee shirt with a blue sky in the background

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Maria Gubbiotti, MD,PhD @mariagoobs.bsky.social · 20/12/2024

Asteroid hyalosis is an aging-associated condition of the eye where calcium and phospholipids build up giving the eye a grossly “glittery star-like” appearance (hence the name). Here is a vitreous cytology specimen before and after polarization showing the material 💫 👁️ #pathsky #medsky

A cytology preparation showing pink amorphous blobs

$Same specimen after polarization highlighting the refractory nature of the material$

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Maria Gubbiotti, MD,PhD @mariagoobs.bsky.social · 06/12/2024

Some tumor look-a-likes on this Friday: Chordoid meningioma and chordoma can share similar features of cords of cells in a myxoid background. Chordoma shows diffuse nuclear Brachyury expression whereas chordoid meningioma is positive for SSTR2 helping to differentiate the two 🧠 #pathsky #neuropath

Smear preparation of a meningioma with chordoid features

Permanent section of a chordoid meningioma showing focal whorl formation

Permanent section of a chordoid highlighting the cords of tumor cells in a myxoid background

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Maria Gubbiotti, MD,PhD @mariagoobs.bsky.social · 03/12/2024

Alternatively, if you are looking for something else consider mailchi.mp/houserabbits... This is where we adopted our adorable bunny Teepah!

A grey and white bunny staring at the camera

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Maria Gubbiotti, MD,PhD @mariagoobs.bsky.social · 28/11/2024

Happy Thanksgiving! Always a time to reflect and be grateful for where we are, where we’ve been, and where we are going 😊 🦃

Fall foliage on the mountain with a pond in the forefront

A blue sky over fall foliage and a corn field

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Reposted by Maria Gubbiotti, MD,PhD

Philadelphia Eagles @philadelphiaeagles.bsky.social · 26/11/2024

Giving back to the community this holiday season 🦃 Along with the Michael Ann & Saquon Barkley Hope Foundation, acmemarkets, and Youth Mentoring Partnership, Saquon provided Thanksgiving meals to 150 families!

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Reposted by Maria Gubbiotti, MD,PhD

Ashley Aaroe MD @ashleyaaroe.bsky.social · 24/11/2024

Looking forward to our SNO Future Leaders team project #SNO2024, engaging students to inspire next generations of neuro-oncologists! Social media fosters these connections, so if you're new here like me just follow everyone @neuroonc.bsky.social is tagging / reposting from the conference!

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Maria Gubbiotti, MD,PhD @mariagoobs.bsky.social · 21/11/2024

My first time at the annual SNO meeting! Excited to share some cases for discussion during education day #sno2024 #pathsky #medsky 🧠 🔬 🧫 🧪

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Reposted by Maria Gubbiotti, MD,PhD

Vanessa Smith @drvanessasmith.bsky.social · 21/11/2024

AMP describing the membership and educational focus of the organization #AMPATH24

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Maria Gubbiotti, MD,PhD @mariagoobs.bsky.social · 18/11/2024

#worldprematurityday2024 Our daughter was born at 28 weeks and is now a happy healthy almost 3 year old! @mjcampbell.bsky.social was amazing and handily played both doctor and dad roles! Fun fact: my dad was also born prematurely (both born in December). Wild to see his picture next to hers!

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Reposted by Maria Gubbiotti, MD,PhD

Dr. Autopsy, DO @drautopsy.bsky.social · 17/11/2024

Beautiful pseudoactinomycotic radiate granules (PAMRAGs) to start your Sunday morning. #pathsky #pathology #pathart

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Maria Gubbiotti, MD,PhD @mariagoobs.bsky.social · 16/11/2024

According to my husband I only have two interests: surgical pathology and horses 😂 This is my OTTB, When You Wish (name credits to @mjcampbell.bsky.social) “Star” who was given to me 7 years ago by one of my early horse mentors (it’s a long story lol). Anyway I love her to pieces #eqbsky 🐎🦋

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Maria Gubbiotti, MD,PhD @mariagoobs.bsky.social · 14/11/2024

It’s almost Friday so here’s a case of metastatic papillary thyroid carcinoma that now shows anaplastic transformation. The late great Dr Livolsi and I did a study on such brain metastases detailing the histologic and molecular features ❤️🧠🔬 #pathsky pubmed.ncbi.nlm.nih.gov/36889238/

Squash preparation showing many cells some with bizarre atypia

Close up view of a highly atypical cell with nuclear pseudoinclusions

H&E stained section showing high grade metastatic thyroid carcinoma with some hobnail features

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Maria Gubbiotti, MD,PhD @mariagoobs.bsky.social · 13/11/2024

Hoping to connect with old friends, make new ones, and find more pathology content to browse (and learn)!

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Maria Gubbiotti, MD,PhD @mariagoobs.bsky.social · 11/11/2024

Myxopapillary ependymoma grossly has a characteristic sausage-shaped appearance. Commonly found associated with the filum terminale, it has a fibrillary glial appearance in a myxoid background. Though previously categorized as CNS WHO grade 1, it is now considered grade 2 #pathsky #medsky #neuropath

A sausage shaped tumor with attached filamentous band

A squash preparation of a fibrillary neoplasm with myxoid background

H&E stained section of papillae with myxoid cores

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Maria Gubbiotti, MD,PhD @mariagoobs.bsky.social · 10/11/2024

Though I used the previous platform solely for medical posts, here is some horse content for #eqbsky 🐎 🦋 Introducing me, Star, and @mjcampbell.bsky.social (follow for pediatric cardiology content!) I especially love this picture because our daughter Madeline (now a toddler lol) is also in it

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Maria Gubbiotti, MD,PhD @mariagoobs.bsky.social · 10/11/2024

Would love to reconnect with the online path community :)

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Maria Gubbiotti, MD,PhD @mariagoobs.bsky.social · 09/11/2024

Nice example of a schwannoma including an intact gross specimen and H&E stained sections showing Verocay body formation and some ancient change 🧠 🔬

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Maria Gubbiotti, MD,PhD @mariagoobs.bsky.social · 07/11/2024

Starting off with a path classic of adenoid cystic carcinoma

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