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Marc Dionne

@marcsdionne.bsky.social
1.5K followers 1.5K following 744 posts

Innate immunity, bacterial infection, physiology, microbiology, Drosophila. Poorly focused. Still angry. Professor, Department of Life Sciences and Centre for Bacterial Resistance Biology, Imperial College London.

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Marc Dionne @marcsdionne.bsky.social · 2h
I can't speak for anyone else, but I know that there are times when I do this. It's because I only know about one of the papers. This is a product, partly, of not interacting with physical journals any more. It obviously can amplify itself, like some chiral catalysts.
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Marc Dionne @marcsdionne.bsky.social · 09/10/2026
We'll all be sick of rain before the reservoirs are full
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Marc Dionne @marcsdionne.bsky.social · 07/10/2026
As a Londoner, very curious regarding the recommendations of the freelance pie advisor
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Marc Dionne @marcsdionne.bsky.social · 04/10/2026
oh wow did they invent GLP-1 agonists
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Marc Dionne @marcsdionne.bsky.social · 30/09/2026
that may make the process slower and more painful
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Reposted by Marc Dionne
Shiv Ramdas Mens Rice Activist @nameshiv.bsky.social · 30/09/2026
I'm kinda fully over that "the British conquered the world for spices and don't use any of them" joke because for one, you cannot recycle material for 5 straight generations and get a laugh worth a damn but also because in order to make it you have to agree with Tommy Robinson about who is British
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Marc Dionne @marcsdionne.bsky.social · 30/09/2026
one is faster and less painful than the other
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Reposted by Marc Dionne
Scare Smith 💀 @evilgalprods.bsky.social · 29/09/2026
FATALITY
A tweet from Joyce Carol Oates: overall takeaway from the Curtis Yarvin profile is that there must be millions of smart-aleck show-offy kids who annoy their teachers and go on to annoy other adults through their lives with their “contrarian” pose that hardens to a carapace over their faces; until, as adults, they still harbor a delusion that, if there is a king, or a fuhrer, he’d be impressed with the guys motor mouth and appoint him to his cabinet rather than deleting him with a negligent swipe of his wrist as Stalin did routinely.
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Marc Dionne @marcsdionne.bsky.social · 25/09/2026
each other
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Marc Dionne @marcsdionne.bsky.social · 25/09/2026
maybe it's just Batesian mimicry
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Marc Dionne @marcsdionne.bsky.social · 17/09/2026
😟 you buried the lede there
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Marc Dionne @marcsdionne.bsky.social · 17/09/2026
Or at least everywhere there are humans. Or, depending on how precisely you define "tuberculosis", mammals.
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Marc Dionne @marcsdionne.bsky.social · 17/09/2026
Dude, there's tuberculosis *everywhere*. There's not a lot of it in Basel, though.
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Marc Dionne @marcsdionne.bsky.social · 17/09/2026
I'm just glad you didn't take that picture yourself.
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Marc Dionne @marcsdionne.bsky.social · 16/09/2026
this picture is deeply disturbing
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Marc Dionne @marcsdionne.bsky.social · 14/09/2026
Honestly, knowing what I do about subjective effects of CB1R agonists, I would be really hard to convince that antagonists would have a useful therapeutic profile.
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Marc Dionne @marcsdionne.bsky.social · 14/09/2026
well, I hope it works...
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Marc Dionne @marcsdionne.bsky.social · 14/09/2026
CB1 antagonists were "previously associated with severe psychological side effects". Those side effects, for those of you playing at home, included anxiety and suicidal ideation.
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Marc Dionne @marcsdionne.bsky.social · 09/09/2026
5 is well over 4, right? Just want to make sure I can make the same claim.
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Marc Dionne @marcsdionne.bsky.social · 09/09/2026
As long as it's worth it to you. If you decide it's not, you can always choose to cycle less and drink more
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Marc Dionne @marcsdionne.bsky.social · 09/09/2026
There's a dry in September now? At least dinner looks good
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Marc Dionne @marcsdionne.bsky.social · 08/09/2026
The last time I needed to get to Heathrow at an hour when the tube wasn't running, Uber flat refused my business. Ended up hailing a black cab, which was expensive, but at least it worked.
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Marc Dionne @marcsdionne.bsky.social · 03/09/2026
surely having direction makes it distinct from classical Starmerism
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Marc Dionne @marcsdionne.bsky.social · 03/09/2026
yes, but sometimes it doesn't show on his face
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Marc Dionne @marcsdionne.bsky.social · 03/09/2026
your correct thing is correct, but—as someone who tried reading one of her other books—I am impressed by the contribution of the editor
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Marc Dionne @marcsdionne.bsky.social · 03/09/2026
um, I don't want you to take this the wrong way, but this paper accepted selfie looks like you have been captured in the act of contemplating your own mortality
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Marc Dionne @marcsdionne.bsky.social · 01/09/2026
not sure that follows
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Marc Dionne @marcsdionne.bsky.social · 01/09/2026
How funny! In our hands, c564/+ is about the most immune-competent "wild-type" stock we ever use. Never known why—I have a vague feeling it may to do with subcritical stress in fat body enhancing immune responsiveness. (Controls always!) It certainly works well as a FB rescue driver for us.
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Marc Dionne @marcsdionne.bsky.social · 01/09/2026
We haven't seen any (we get melanotic tumors in c564, more than anything). For us, Lpp is strong and well-behaved, with the important caveat that Lpp-Gal4 expression shuts down for several hours after infection, which is why we use c564 a lot anyway.
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Marc Dionne @marcsdionne.bsky.social · 30/08/2026
A sambal oelek to remember
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Marc Dionne @marcsdionne.bsky.social · 30/08/2026
reminds me of the time my mother substituted habaneros for jalapenos in the jalapeno lime mint sorbet
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Marc Dionne @marcsdionne.bsky.social · 29/08/2026
My Dinner with Thiago
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Marc Dionne @marcsdionne.bsky.social · 28/08/2026
well, I mean, you could replace them with some entirely new woes
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Marc Dionne @marcsdionne.bsky.social · 26/08/2026
I'm disappointed you didn't pull "Even different types of immunologists, such as those working on the innate versus adaptive immune systems, did not always talk to each other very effectively." No shit?
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Marc Dionne @marcsdionne.bsky.social · 26/08/2026
I'm pleased and relieved not to find Cell Signaling Technology on this list
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Marc Dionne @marcsdionne.bsky.social · 25/08/2026
it's about the journey, not the destination
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Marc Dionne @marcsdionne.bsky.social · 18/08/2026
and the dung-balls fresh
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Marc Dionne @marcsdionne.bsky.social · 18/08/2026
never without you, mon vieux
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Marc Dionne @marcsdionne.bsky.social · 18/08/2026
Clearly we hang out at different bars
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Marc Dionne @marcsdionne.bsky.social · 17/08/2026
And then there's Audubon. “The flesh of this Petrel was fat, but tough, with a strong smell, and unfit for food; for, on tasting it, as is my practice, I found it to resemble that of the porpoises.” usbirdhistory.com/audubon-eati...
usbirdhistory.com
Eating the Birds of America: Audubon’s Culinary Reviews of America’s Birds - US Bird History
On June 26, 1826, John James Audubon sat aboard the cotton schooner Delos off of Florida’s Gulf coast, en route from New Orleans to Liverpool, where he was hoping to find a publisher for his extensive...
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Marc Dionne @marcsdionne.bsky.social · 17/08/2026
There will be an open information session on 9th September 2026 at 11am: teams.microsoft.com/dl/launcher/... Apply/more info here: www.imperial.ac.uk/jobs/search-...
imperial.ac.uk
Description
Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...
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Marc Dionne @marcsdionne.bsky.social · 17/08/2026
Be my colleague! We are seeking Assistant/Associate Professors in these areas: Immunology, including but not limited to cellular immunology Infection, Bacteriology or Microbiology This is a good place to work, with excellent students and colleagues and an interactive, encouraging environment.
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Marc Dionne @marcsdionne.bsky.social · 22/07/2026
"hormone" is very obviously a mistranslation of "human"
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Marc Dionne @marcsdionne.bsky.social · 19/07/2026
nice boid
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Marc Dionne @marcsdionne.bsky.social · 17/07/2026
I was hoping for raisins
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Marc Dionne @marcsdionne.bsky.social · 10/07/2026
whereas, today, my entire experience of travel agents is through the deals requiring or encouraging their use for work travel, which leads me to the conclusion that they have made a transition to being obligate parasitoids, consuming and eventually destroying their host
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Marc Dionne @marcsdionne.bsky.social · 08/07/2026
does a fish know what water is?
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Marc Dionne @marcsdionne.bsky.social · 03/07/2026
Sure, if greenland sharks regard their sprogs as precious widdle cutiepies, but if they put the little bastards to work in the squid mines while adults float around waiting for a dead polar bear to float by, birth rates should be going up. We know so little about life in the benthic zone.
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Marc Dionne @marcsdionne.bsky.social · 03/07/2026
tbf the USA is already older than many Greenland sharks
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Marc Dionne @marcsdionne.bsky.social · 30/06/2026
asking this question shows that you know the answer
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