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marcelkeller.bsky.social

@marcelkeller.bsky.social
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Meriam Guellil PhD @meriamguellil.bsky.social · 15/09/2026
I am opening a PhD position at the University of Vienna to work with me on ancient pathogen aDNA 🦠🧬 Please help spread the word to any relevant candidates or contact me if you are interested! Join us here in Vienna!
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Christina Warinner @christinawarinner.bsky.social · 11/09/2026
A huge congratulations to Tessa Zeibig for her first dissertation publication about ancient parvovirus B19! It was such a pleasure to collaborate on this study!
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Kevin Daly @gingerhowley.bsky.social · 02/09/2026
Our paper on ancient sheeppox virus genomes, including many found from parchment samples, is now published af Science Advances. Congrats to all our co-authors and particularly first author Louis. #aDNA share.google/JqVOTB2lvxcO...
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Three thousand five hundred years of sheeppox virus evolution inferred from archaeological and codicological genomes
Sheeppox virus (SPPV) is a major livestock pathogen causing economic hardship through reduced production and death of vulnerable sheep, with written descriptions of sheeppox-like disease recorded sinc...
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marcelkeller.bsky.social @marcelkeller.bsky.social · 11/09/2026
7) With our refined phylochronology, we decided to reassess all published genomes along with our new ones, resulting in a 60-page SI section, providing a critical discussion of all data, our reasoning, and primary sources supporting the suggested plague outbreaks associated with the genomes.
Table 2 of the paper showing previously published genomes and the historically recorded outbreaks they are putatively linked to.
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marcelkeller.bsky.social @marcelkeller.bsky.social · 11/09/2026
6) We identify several clusters of identical genomes, i.e. incidents in which strains spread widely without accumulating additional mutations. One of those events (N18) happened in the Baltic region right after the Little Polytomy (N16), highlighting this period as particularly proliferative.
Cutout of the schematic tree highlighting the Little Polytomy and the closely related cluster of identical Baltic genomes.
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marcelkeller.bsky.social @marcelkeller.bsky.social · 11/09/2026
5) Working with non-UDG data is challenging, since environmental contamination cannot be easily filtered while allowing for deamination damage. We developed 2 new approaches to reduce the # of false SNPs in those genomes without affecting phylogenetically informative positions.
Plots showing the number of private SNPs of non-UDG-derived genomes after different treatments as well as pairwise statistics.
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marcelkeller.bsky.social @marcelkeller.bsky.social · 11/09/2026
4) In the absence of sufficient RC metadata, we applied a generic offset and got satisfactory results that we could cross-validate against other chronological data. Despite the increased uncertainty through applying a generic offset, our model was able to significantly shorten the RC intervals.
Figure showing the plot for the main radiocarbon model and box plots showing the distribution of radiocarbon spans and intervals before and after modeling.
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marcelkeller.bsky.social @marcelkeller.bsky.social · 11/09/2026
3) Modeling with uncorrected radiocarbon dates results in poor support since several RC dates appear too old. We conclude that RC dates of human remains are often affected by reservoir effects and offsets that need to be considered in contexts where a difference of a decade changes the whole story.
Clipping from a radiocarbon modeling plot showing low agreement indices for two radiocarbon dates.
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marcelkeller.bsky.social @marcelkeller.bsky.social · 11/09/2026
2) We describe a Little Polytomy around 1450-1500 that gave rise to two major clades and – to our current knowledge – additional short-lived clades. Another lineage surviving for at least a century branching just one SNP before, suggesting that several new reservoirs were seeded during this period.
Phylogenetic and schematic tree of the Second Pandemic genomes.
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marcelkeller.bsky.social @marcelkeller.bsky.social · 11/09/2026
Some highlights: 1) We identify repeated introductions of plague into Estonia, from the late 14th c. until one of the last major outbreaks in 1710 during the Great Northern War. We found plague victims at both urban and rural sites, showing how well-connected the region was to the rest of Europe.
Map showing the location of all plague genomes of the Second Pandemic.
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marcelkeller.bsky.social @marcelkeller.bsky.social · 11/09/2026
Our paper on the second plague pandemic is now finally published: www.pnas.org/doi/10.1073/... We present 11 new Y. pestis genomes from around Europe and introduce a new approach to refine the dating of ancient genomes that helped us to contextualize 75 plague genomes of the Second Pandemic.
Schematic workflow showing the Phylogenetically Informed Radiocarbon Modeling
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SPAAM @spaam-community.bsky.social · 07/11/2025
🗳️🗳️Dear SPAAM community, have you voted for the SPAAM8 2026 meeting location yet? The poll is open until Nov 22! Check Element General Room to choose your preferred option (Leipzig, Copenhagen, Stockholm, or online). Your input matters—help shape our next annual meeting!
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Lucy van Dorp @lucyvandorp.bsky.social · 01/09/2025
Excited to say we’re hiring 😊. We’re looking for a post-doc in ancient pathogen genomics to join our friendly supportive team in London at @ugiatucl.bsky.social. Start date January 2026. www.ucl.ac.uk/work-at-ucl/...
ucl.ac.uk
UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
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Lehti Saag @lehtisaag.bsky.social · 23/04/2025
Happy to announce an open call for a funded PhD position! 📊 Research project: Elucidating the fine-scale demographic history of the Eastern Baltic by incorporating haplotype-based analyses and modelling 📍 Institute of Genomics, University of Tartu 📩 Application period: 1st–15th May 2025
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i-light-maka.bsky.social @i-light-maka.bsky.social · 10/02/2025
Finally getting some of my research for my PhD out there! Hopefully soon in a journal near you ;) Ancient Y. pestis infection from a sheep falls on the LNBA lineage, previously only known from humans! +molecular evolutionary analysis to leverage the ever increasing number of ancient genomes known!
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