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Marc Duque Ramirez

@marcduque.bsky.social

NeuroPhD candidate @Engert Lab. Interested in new neuromodulation techniques and molecular approaches to understand how the brain works.

Posts Replies Media

Marc Duque Ramirez @marcduque.bsky.social · 17/04/2025

Check it out!

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Marc Duque Ramirez @marcduque.bsky.social · 22/12/2024

3/3 We haven't tested in fish yet, but I wonder if there would be a significant difference in the glial calcium effect between DXM alone and DXM + bup. Thanks again for bringing this up!

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Marc Duque Ramirez @marcduque.bsky.social · 22/12/2024

2/3 I also wondered if this could explain the observed synergy between NMDAR antagonism and NE reuptake inhibition, such as with DXM and bupropion, although I'm sure there's many different mechanisms at play.

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Marc Duque Ramirez @marcduque.bsky.social · 22/12/2024

1/3 That is fascinating thanks so much for sharing! Looking forward to what you see in terms of non-responders for prazosin and other alpha-1 antagonists.

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Marc Duque Ramirez @marcduque.bsky.social · 25/11/2024

www.nature.com/articles/s41... Very exciting paper - still need to go through all of it, but already liked the use of cOpn5 to stimulate astrocytes. Potentially interesting if ATP and glutamate are released through independent mechanisms

nature.com

Astrocytes release ATP/ADP and glutamate in flashes via vesicular exocytosis - Molecular Psychiatry

Molecular Psychiatry - Astrocytes release ATP/ADP and glutamate in flashes via vesicular exocytosis

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Reposted by Marc Duque Ramirez

Neil Shubin @neilshubin.bsky.social · 24/11/2024

Your reminder that many of the muscles, nerves and bones you use to hear and talk with correspond to gill structures in fish. 🧪 #evolution #paleontology

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