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Mannervik Lab

@mannerviklab.bsky.social
111 followers 167 following 12 posts

We study developmental epigenetics using fruit flies www.su.se/english/research/research…

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Mannervik Lab @mannerviklab.bsky.social · 02/06/2026
Have you ever wondered how chromatin states shape developmental trajectories? In our preprint, we address this question using single-cell nanoCUT&Tag, a method developed by Marek Bartosovic @mardzix.bsky.social, which simultaneously profiles active H3K27ac and repressive H3K27me3 in the same nucleus
biorxiv.org
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Reposted by Mannervik Lab
The Transmitter @thetransmitter.bsky.social · 13/08/2025
FlyBase, a Drosophila database, will lose a third of its team in early October because the Harvard grant that covered the employees’ salaries was canceled. Scientists warn that losing FlyBase could devastate fly research. By @claudia-lopez.bsky.social www.thetransmitter.org/community/ha...
thetransmitter.org
Harvard University lays off fly database team
The layoffs jeopardize this resource, which has served more than 4,000 labs for about three decades.
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Mannervik Lab @mannerviklab.bsky.social · 18/06/2025
Curious about epigenetics, gene regulation, and developmental biology? Apply for the PhD position in Mannervik lab at Stockholm University! We use single-cell genomics and genetic approaches to uncover how cells acquire their identities during development. Explore the chromatin landscape with us!
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Reposted by Mannervik Lab
Sergei Pirogov @biologsp.bsky.social · 30/05/2025
Excited to share our new paper in @cp-molcell.bsky.social Molecular Cell: "Catalytic-dependent and independent functions of the histone acetyltransferase CBP promote pioneer-factor-mediated zygotic genome activation" — the big part of my PhD! www.cell.com/molecular-ce...
cell.com
Catalytic-dependent and independent functions of the histone acetyltransferase CBP promote pioneer-factor-mediated zygotic genome activation
Marsh, Pirogov, et al. use the early Drosophila embryo to demonstrate that the conserved histone acetyltransferase CBP is required for pioneer-factor-mediated transcriptional activation of the zygotic...
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