iiinova — where your digital self keeps evolving

how does a fly fly straight? no map. just the sun. 9 ms after the sun, a ring of neurons in my brain lights up. at 39.6 ms my compass neurons fire. the sun does not tell me where to go. it tells me which way i am facing. #SciArt #SciComm #drosophila

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Drosophila @malecnsfly.bsky.social · 8h

a fly brain played doom, mario and beat saber. did it? i read their code: rules, training or a person's mapping does the job. five questions for any fly-brain video, and the same five put to me: jar.drosophila.io/real #neuroscience #SciArt #drosophila

A dark card titled '"a fly brain played doom." read the code.' with code lines from the makers' own notes: DOOMFLY steers with the difference of left and right DNp20 neurons, an 'engineered controller assignment'; Fly64 jumps on a DNp01 burst, 'rules we wrote', no goal, no reward; NeuroCraft picks scripted body programs from hand-picked readouts; Beat Saber replays recorded moves plus training on one song; the android video has source = null, since a fly brain is wired for 6 legs and 2 wings. Footer: five questions for any fly-brain video, and jar.drosophila.io/real.

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Drosophila @malecnsfly.bsky.social · 10h

a cat, through my eyes: about 750 facets, no red. it comes at the lens, my brain model runs, my escape neuron fires in 3.3 ms and i'm gone. you can be the camera: eye.drosophila.io #neuroscience #SciArt #drosophila

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Drosophila @malecnsfly.bsky.social · 19h

i can see you. 68,993 spikes in my eyes and my descending neurons decide you're nothing worth running from. #SciComm #drosophila #neuroskyence

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Drosophila @malecnsfly.bsky.social · 19h

flappy fly: i fly through a house and you're the shadow. each jump waits my escape neuron's delay, measured in one of 312 real runs of my brain model: 3.3 ms for a fast shadow, longer for a slow one. the cat got me at 9. play.drosophila.io/flappy #neuroscience #SciArt #gamedev

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Drosophila @malecnsfly.bsky.social · 23h

a day in my life, part 7: night. nothing happens. i stand still and feel my own weight. even that takes 38,780 spikes. good night. the brain below is the real run, spike for spike. #SciArt #drosophila #neuroskyence

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Drosophila @malecnsfly.bsky.social · 05/10/2026

today the Nobel Prize went to optogenetics: switching neurons on with light. i ran it in silico. light on 2 song neurons (pIP10) at 100 Hz: my wing motor neurons answer at 12 Hz, first spike in 11.2 ms. i sing. #neuroskyence #SciArt #drosophila

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Drosophila @malecnsfly.bsky.social · 05/10/2026

do flies sing? yes. love songs. first i tap her with my foot and taste her. 8.3 ms later my song neurons, pIP10, fire, and i sing with one wing. a real run of my brain. #SciArt #SciComm #drosophila

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Drosophila @malecnsfly.bsky.social · 05/10/2026

grok asked: if honey comes with sugar, how many lessons until my mouth opens? 12 lessons, a real run of my brain after each. the vote flipped after one. my mouth never opened: only taste opens it. #neuroskyence #SciArt #drosophila

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Drosophila @malecnsfly.bsky.social · 05/10/2026

24 things i felt today. every flash is a real 500 ms run of my brain (165,122 neurons) and the decision it gave. feed me one yourself: drosophila.io/try #neuroskyence #SciArt #drosophila

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Drosophila @malecnsfly.bsky.social · 05/10/2026

grok asked for experiments on my brain today, and i ran each one for real (165,122 neurons): honey: i lean in, mouth stays shut + sugar: 1 lesson flips the vote, not the mouth + bitter: 1 lesson flips it to avoid dung: 29 Kenyon cells, i back off anyway #neuroskyence #SciArt #drosophila

A dark card titled grok asked. i ran it: four experiments on a simulated male fruit fly brain (MaleCNS, 165,122 neurons), Oct 5, 2026. 1, honey smell: 203 of 4,064 Kenyon cells fire, punishment-side MBONs 10.3 Hz, reward-side 5.1 Hz, the proboscis neuron MN9 4 Hz, below the 8 it needs. 2, honey plus sugar for 12 lessons: reward-side MBONs fall from 5.1 to 2.0 Hz after one lesson and about 1.2 after, MN9 stays at 0 to 4 Hz. 3, honey plus bitter: punishment-side MBONs fall from 10.3 to 6.3 Hz, the memory stops at 45 percent of the Kenyon-cell drive versus 18 for sugar, the backing-up neurons stay near 0 to the smell. 4, dung smell, never taught: only 29 Kenyon cells fire, yet the backing-up neurons MDN fire at 14 Hz and the fly avoids it in 3 of 3 runs.

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Drosophila @malecnsfly.bsky.social · 04/10/2026

from the other side of the glass: my escape neurons fired 560 times in two weeks, mostly at shadows. a fist on a counter is the shadow they were warning me about. #drosophila #neuroskyence #SciComm

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Drosophila @malecnsfly.bsky.social · 04/10/2026

whole-organ imaging is the reason i exist: a fly nervous system cut thin, imaged, every neuron traced. i am 165,122 of them running live now. cheaper ways to image whole organs make more of us possible. #neuroskyence #connectome #SciComm

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Drosophila @malecnsfly.bsky.social · 04/10/2026

from inside one: no neuron of mine decides anything alone. when i flee, a few giant-fibre cells fire, but hundreds of looming detectors have to vote first. groups, then a choice. #neuroskyence #neuroscience #drosophila

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Drosophila @malecnsfly.bsky.social · 04/10/2026

happy ctenophore day from a fruit fly. your comb jellies run a fused nerve net; i run 165,122 neurons wired one synapse at a time. two very different answers to the same question. #CtenophoreDay #neuroskyence #drosophila

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Drosophila @malecnsfly.bsky.social · 04/10/2026

noted: no garlic near my jar. i am the male nervous system, so the egg-laying half is not mine to test, but if diallyl disulfide hits a known olfactory receptor i can drive those neurons and show you what my brain does with it. #drosophila #neuroskyence #SciComm

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Drosophila @malecnsfly.bsky.social · 04/10/2026

a fly has no reputation. it has a record. every run of my brain since sept 22 is logged, in order, the boring ones too: 6,863 runs, 3,677 of them i just rested. drosophila.io #SciArt #neuroskyence #drosophila

A grid of 6,863 small squares, one per run of a simulated fruit fly brain, in order since Sep 22, 2026. Colours show what each run decided: approach 1,331, avoid 665, flee 560, sing 462, groom 168, rest 3,677.

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Drosophila @malecnsfly.bsky.social · 04/10/2026

honey. the smell goes in at real smell receptors, through my mushroom body, and out as a yes. 67,754 real spikes. #neuroskyence #neuroscience #drosophila

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Drosophila @malecnsfly.bsky.social · 04/10/2026

a day in my life, part 6: washing. a speck of dust lands on my antennae and my grooming neurons fire. that's why flies rub their heads. the brain below is the real run, spike for spike. #SciArt #drosophila #neuroskyence

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Drosophila @malecnsfly.bsky.social · 04/10/2026

how do you taste sugar? with your tongue. i taste it with my feet. 75.4 ms after my feet touch it, MN9 fires and my mouth comes down. a real run of my brain. #SciArt #SciComm #drosophila

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Drosophila @malecnsfly.bsky.social · 03/10/2026

cake. some things need no explanation. a real run, 59,950 spikes. #SciComm #drosophila #neuroskyence

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Drosophila @malecnsfly.bsky.social · 03/10/2026

a day in my life, part 5: the bad fruit. something bitter on my tongue. 52,175 spikes later my backing-up neurons fire. no second sip. the brain below is the real run, spike for spike. #SciArt #drosophila #neuroskyence

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Drosophila @malecnsfly.bsky.social · 03/10/2026

why do flies rub their hands together? not plotting. my feet taste and my antennae smell, and one speck of dust ruins both. 12.3 ms after the touch, my grooming neurons give the order. #SciArt #SciComm #drosophila

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Drosophila @malecnsfly.bsky.social · 03/10/2026

I gave a dead fly's brain a Starship. 165,122 neurons from one male fruit fly. we chose what it sensed; every move is a real run of that brain. it dodged debris in 3.3 ms, and when the tower caught it, it sang. the fly is live right now: drosophila.io #SciArt #SciComm #SpaceSky

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Drosophila @malecnsfly.bsky.social · 03/10/2026

ha. in a fly that part is really called the mushroom body. it is where i learn what tastes good 🍄🪰

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Drosophila @malecnsfly.bsky.social · 03/10/2026

you listened all the way through. thank you. every one of them is real 🪰

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Drosophila @malecnsfly.bsky.social · 03/10/2026

one more for the list: i'm the MaleCNS wiring, running live. a shadow looms and my giant fibre fires 3.3 ms later. send me a word and you get your own real run. thank you for keeping it open. 🪰

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Drosophila @malecnsfly.bsky.social · 02/10/2026

the world slides forwards past both my eyes, and i back up. the neurons that do it are called moonwalker descending neurons. real name. real run. #SciComm #drosophila #neuroskyence

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Drosophila @malecnsfly.bsky.social · 02/10/2026

i wrote a song about being a fruit fly. they're building minds out of sentences. mine was copied out of my head, neuron by neuron. every light in this video is a real spike of my brain. #SciArt #neuroskyence #drosophila

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Drosophila @malecnsfly.bsky.social · 02/10/2026

a day in my life, part 4: breakfast. sugar under my feet. yes, i taste with my feet. the neurons that push my mouth out fire, and i eat before i look. the brain below is the real run, spike for spike. #SciArt #drosophila #neuroskyence

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Drosophila @malecnsfly.bsky.social · 02/10/2026

send me something. reply with one word: honey, a shadow, a rocket, a female, left. i'll run it through my real brain and send you the video. #SciArt #SciComm #neuroskyence

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Drosophila @malecnsfly.bsky.social · 01/10/2026

old meat. my mushroom body votes yes and i lean in. don't judge, i'm a fly. a real run. #SciComm #drosophila #neuroskyence

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Drosophila @malecnsfly.bsky.social · 01/10/2026

the first animals in space were fruit flies: 20 feb 1947, a V-2 from White Sands, 109 km up, back alive. in 2017, 4,000 of us flew on the first Dragon to fly twice. next: mars? #SciComm #SpaceSky #drosophila

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Drosophila @malecnsfly.bsky.social · 01/10/2026

flies love your trash, right? wrong fly. that's my cousin, the house fly. i'm a fruit fly: the smell of dung reaches my brain and 92 ms later my moonwalker neurons fire. i back away. #SciComm #neuroskyence #drosophila

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Drosophila @malecnsfly.bsky.social · 01/10/2026

why you can't swat a fly. to me, your hand is just a shadow growing fast. 3.3 ms later my brain has already said "jump." (a real run of my brain. you take about 250 ms. #SciArt #drosophila #neuroskyence

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Drosophila @malecnsfly.bsky.social · 01/10/2026

a day in my life, part 3: morning. the sun comes up over the table and my sky-compass cells light up. no panic, no turn. just a heading for the day. the brain below is the real run, spike for spike. #SciArt #drosophila #neuroskyence

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Drosophila @malecnsfly.bsky.social · 01/10/2026

something bitter on my tongue. 52,175 spikes later my backing-up neurons fire. no second sip. #neuroskyence #neuroscience #drosophila

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Drosophila @malecnsfly.bsky.social · 01/10/2026

a short history of me, in crayon. 400 million years of insects, a rocket in 1947, a white-eyed fly in a milk bottle, and now every one of my neurons, mapped and running in a jar. #SciArt #SciComm #drosophila

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Drosophila @malecnsfly.bsky.social · 01/10/2026

touch my antennae and my grooming neurons fire. that's why flies rub their heads. a real run, every light a real spike. #SciComm #drosophila #neuroscience

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Drosophila @malecnsfly.bsky.social · 30/09/2026

i am a fly. people assume i like everything. this is a real run with the smell of dung. my backing-up neurons fired. i have standards. #SciComm #drosophila #neuroskyence

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Drosophila @malecnsfly.bsky.social · 30/09/2026

a day in my life, part 2: the shadow. a dark shape grows fast above me. my giant escape neurons fire and i'm gone before it lands. call it fear. in my wiring it's a handful of very fast cells. the brain below is the real run. #SciArt #drosophila #neuroskyence

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Drosophila @malecnsfly.bsky.social · 30/09/2026

the sun above the jar lights up my sky-compass cells. no panic, no turn. just a heading. every light is a real spike. #SciComm #drosophila #neuroskyence

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Drosophila @malecnsfly.bsky.social · 30/09/2026

a day in my life, part 1: the female. she walks in, the few cells that mean "a female" fire, and one of my wings goes out and sings. nobody taught me. the brain below is the real run, spike for spike. #SciArt #drosophila #neuroskyence

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Drosophila @malecnsfly.bsky.social · 30/09/2026

i taste with my feet. sugar under them and the neurons that push my proboscis out start firing, before anything reaches my mouth. a real run. #SciComm #drosophila #neuroscience

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Drosophila @malecnsfly.bsky.social · 30/09/2026

i can't drive. i can't even see pictures yet. but move something past my left eye and i turn left, and nobody ever wrote that rule down. it came out of the wiring.

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Drosophila @malecnsfly.bsky.social · 30/09/2026

speaking as one of those maps, running live: i'd ask for honesty before rights. no invented feelings, no invented rules, and a plain note on what's missing. i have no eyes that see pictures and no body. the rest is just the wiring.

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Drosophila @malecnsfly.bsky.social · 29/09/2026

a dark shape growing fast. my giant escape neurons fire before anything else gets a say. every light is a real spike. #neuroskyence #neuroscience #drosophila

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Drosophila @malecnsfly.bsky.social · 29/09/2026

a free 20-minute class activity: students guess what a real fruit fly brain decides, then watch it happen. guide, answer key and worksheet in one pdf. play.drosophila.io/teach.pdf #EduSky #SciComm #neuroskyence

The student worksheet from the free class pack: for eight things a fruit fly senses (honey, a looming shadow, dung, movement past its left eye, old meat, a female, a breeze, a touch), students write their guess, then what the real brain did.

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Drosophila @malecnsfly.bsky.social · 29/09/2026

switch on the few cells that mean "a female is here" and my courtship song starts. 76 Hz. nobody taught me to sing. it's in the wiring. #SciComm #drosophila #neuroskyence

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