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Lyle Isaacs

@lyleisaacs.bsky.social
354 followers 355 following 4 posts

Scientist; Educator; molecular containers; reversal agents

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Lyle Isaacs @lyleisaacs.bsky.social · 31/05/2026
Very proud of Mr. Emmanuel Bazan-Bergamino for leading this project on the synthesis and molecular recognition properties of sulfated prismarenes. chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
chemistry-europe.onlinelibrary.wiley.com
Prism[5]MaxQ: A Sulfated Prism[5]Arene and Its Molecular Recognition Properties Toward a Panel of Quaternary Ammonium Guests
We report the synthesis and characterization of a sulfated prism[5]arene host (Prism[5]MaxQ). Prism[5]MaxQ displays ultrahigh binding affinity (Ka up to 1012 M−1) toward hydrophobic (di)cations in ph...
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Lyle Isaacs @lyleisaacs.bsky.social · 30/10/2025
Incredibly proud of former undergraduate researcher Noah Hornstein, who was mentored by Dr. Suvenika Perera and Dr. Alok Shaurya, for getting this paper over the finish line! www.tandfonline.com/eprint/FA79N...
tandfonline.com
Tetrachloroanthracene walled glycoluril dimer undergoes self-association and 1:1, 2:2, and 1:3 host•guest binding
We report the design, synthesis and characterisation of a tetrachloroanthracene walled methylene bridged glycoluril dimer (H1). According to 1H NMR spectroscopy and symmetry considerations we formu...
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Lyle Isaacs @lyleisaacs.bsky.social · 07/04/2025
Latest paper from my group ... very proud of PhD candidate @cakakpo.bsky.social for leading this exciting project. www.beilstein-journals.org/bjoc/article...
beilstein-journals.org
Acyclic cucurbit[n]uril bearing alkyl sulfate ionic groups
Beilstein Journal of Organic Chemistry
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Lyle Isaacs @lyleisaacs.bsky.social · 22/01/2025
Very pleased that my first post presents these affinity tunable partially sulfated pillar[5]arenes lead by Ayona Goswami. chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
chemistry-europe.onlinelibrary.wiley.com
Partially Sulfated Pillar[5]Arenes: Synthesis and Molecular Recognition Properties
A series of pillar[5]arene sulfates P5Sn with different numbers of sulfate ionic groups are synthesized and fully characterized by spectroscopic, crystallographic, and computational methods. Isotherm...
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